Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Marie Shibasaki"'
Autor:
Tomomi Kono, Marie Shibasaki, Eika Higashi, Jun Nikaido, Shigeto Hirayama, Hiroko Ikeda, Hideaki Fujii, Junzo Kamei, Ayaka Honjo
Publikováno v:
ACS chemical neuroscience. 10(9)
Our previous results showed that naltrindole (NTI) derivatives with certain types of electron-withdrawing groups as an N-substituent showed δ opioid receptor (DOR) inverse agonistic activities. We therefore synthesized N-acylated NTI derivatives 3a-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee63c42f09af358c48fdb79ab252825f
https://pubmed.ncbi.nlm.nih.gov/31397148
https://pubmed.ncbi.nlm.nih.gov/31397148
Autor:
Riho Kobayashi, Akiyoshi Saitoh, Daisuke Yamada, Marie Shibasaki, Hideaki Fujii, Kennosuke Itoh, Moeno Nishida, Ayaka Honjo, Yota Uchida, Shigeto Hirayama, Toshinori Yoshioka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127176
We have recently reported that the elaboration of the N-substituent in the δ opioid receptor (DOR) antagonist naltrindole (NTI) enabled the regulation of the DOR activities from full inverse agonists to weak partial agonists. The investigations of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519fc60f4863f02530f9a635b09c7d55
https://doi.org/10.1016/j.bmcl.2020.127176
https://doi.org/10.1016/j.bmcl.2020.127176