ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

Autor: Lena Cook, Marie Sengelmann, Birte Winkler, Constanze Nagl, Sarah Koch, Uwe Schlomann, Emily P. Slater, Miles A. Miller, Elke Pogge von Strandmann, Bastian Dörsam, Christian Preußer, Jörg W. Bartsch

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 4; Pages: 1976
Publikationen im Open Access gefördert durch die UB

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed

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