Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Marie SARAZIN"'
Autor:
Fanny Eysert, Paula-Fernanda Kinoshita, Julien Lagarde, Sandra Lacas-Gervais, Laura Xicota, Guillaume Dorothée, Michel Bottlaender, Frédéric Checler, Marie-Claude Potier, Marie Sarazin, Mounia Chami
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Mitochondrial dysfunctions are key features of Alzheimer’s disease (AD). The occurrence of these disturbances in the peripheral cells of AD patients and their potential correlation with disease progression are underinvestigated. We studied
Externí odkaz:
https://doaj.org/article/c121b4ea0df94f49962210d816a22ca2
Autor:
Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Camille Noiray, Stéphane Lehericy, Romain Valabrègue, Fabien Caillé, Philippe Gervais, Martin Moussion, Michel Bottlaender, Marie Sarazin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background The locus coeruleus (LC) and the nucleus basalis of Meynert (NBM) are altered in early stages of Alzheimer’s disease (AD). Little is known about LC and NBM alteration in limbic-predominant age-related TDP-43 encephalopathy (LATE
Externí odkaz:
https://doaj.org/article/283489cd1ad14008b765a46806349f86
Autor:
Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Sébastian Rodrigo, Philippe Gervais, Fabien Caillé, Martin Moussion, Michel Bottlaender, Marie Sarazin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Monitoring the progression of Tau pathology makes it possible to study the clinical diversity of Alzheimer’s disease. In this 2-year longitudinal PET study, we aimed to determine the progression of [18F]-flortaucipir binding and
Externí odkaz:
https://doaj.org/article/0ad53e566d6a402ab083f0d09cdcccb5
Autor:
Jean M. Delabar, Julien Lagarde, Marta Fructuoso, Ammara Mohammad, Michel Bottlaender, Eric Doran, Ira Lott, Isabelle Rivals, Frederic A. Schmitt, Elizabeth Head, Marie Sarazin, Marie-Claude Potier
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Early markers are needed for more effective prevention of Alzheimer’s disease. We previously showed that individuals with Alzheimer’s disease have decreased plasma DYRK1A levels compared to controls. We assessed DYRK1A in the plasma of c
Externí odkaz:
https://doaj.org/article/5d6a3bb197104b249fcbd404915e0cfc
Autor:
Alexandra Pham-Scottez, Thierry Gallarda, Mathilde Calvez, Jérôme Silva, David Barruel, Valérie Dauriac-Le Masson, Justine Lahaye, Florence Perquier, Marie Sarazin, Raphaël Gourevitch
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Despite an increasing number of adults older than 60 years with psychiatric disorders, there are few studies on older patients in psychiatric emergencies and no European data. We aimed to describe the population of patients aged 60 years and older wh
Externí odkaz:
https://doaj.org/article/88a077f4c7ab416daeaa3233d3bfe94d
Autor:
Laura Xicota, Julien Lagarde, Fanny Eysert, Benjamin Grenier-Boley, Isabelle Rivals, Alexandra Botté, Sylvie Forlani, Sophie Landron, Clément Gautier, Cecilia Gabriel, Michel Bottlaender, Jean-Charles Lambert, Mounia Chami, Marie Sarazin, Marie-Claude Potier
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Morphological alterations of the endosomal compartment have been widely described in post-mortem brains from Alzheimer’s disease (AD) patients and subjects with Down syndrome (DS) who are at high risk for AD. Immunostaining with antibodies
Externí odkaz:
https://doaj.org/article/b7f30749fb61429fb9afbbc24d6f5c53
Autor:
Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Philippe Gervais, Claude Comtat, Fabien Caillé, Michel Bottlaender, Marie Sarazin
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract We aimed to investigate the amyloid and tau PET imaging signatures of patients with amnestic syndrome of the hippocampal type (ASHT) and study their clinical and imaging progression according to their initial PET imaging status. Thirty-six p
Externí odkaz:
https://doaj.org/article/c0707097c0e84dfea41c16abdd6a31be
Autor:
Pauline Olivieri, Lorraine Hamelin, Julien Lagarde, Valérie Hahn, Elodie Guichart-Gomez, Carole Roué-Jagot, Marie Sarazin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-6 (2021)
Abstract Background Very-early-onset Alzheimer’s disease (young-AD) differentiates from late-onset AD (old-AD) by a predominant involvement of the parietal neocortex leading to atypical presentations. The diagnosis of AD is often not the first to b
Externí odkaz:
https://doaj.org/article/e46b153ac0d6428db2c2af1d0f2b750b
Autor:
Kunie Ando, Lorenzo Ferlini, Valérie Suain, Zehra Yilmaz, Salwa Mansour, Isabelle Le Ber, Cécile Bouchard, Karelle Leroy, Alexandra Durr, Fabienne Clot, Marie Sarazin, Jean-Christophe Bier, Jean-Pierre Brion
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/5d27c16f0c9d4419b2b9151ff3a7f20c
Autor:
Alexa Haeger, Jean-François Mangin, Alexandre Vignaud, Cyril Poupon, Antoine Grigis, Fawzi Boumezbeur, Vincent Frouin, Jean-Robert Deverre, Marie Sarazin, Lucie Hertz-Pannier, Michel Bottlaender, the SENIOR team
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background Current demographic trends point towards an aging society entailing increasing occurrence and burden of neurodegenerative diseases. In this context, understanding physiological aging and its turning point into neurodegeneration is
Externí odkaz:
https://doaj.org/article/5d1d50a2390346e98f2487c37325913d