Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marie Parat"'
Autor:
Traian Sulea, Jason Baardsnes, Matthew Stuible, Nazanin Rohani, Anh Tran, Marie Parat, Yuneivy Cepero Donates, Mélanie Duchesne, Pierre Plante, Guneet Kour, Yves Durocher
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266250 (2022)
The SARS coronavirus 2 (SARS-CoV-2) spike (S) protein binding to the human ACE2 receptor is the molecular event that initiates viral entry into host cells and leads to infection and virus replication. There is a need for agents blocking viral entry i
Externí odkaz:
https://doaj.org/article/8b6eba9df05d411880bdd994868f66fa
Autor:
Anne E.G. Lenferink, Paul C. McDonald, Christiane Cantin, Suzanne Grothé, Mylene Gosselin, Jason Baardsnes, Myriam Banville, Paul Lachance, Alma Robert, Yuneivy Cepero-Donates, Stevo Radinovic, Patrick Salois, Marie Parat, Hafida Oamari, Annie Dulude, Mehul Patel, Martin Lafrance, Andrea Acel, Nathalie Bousquet-Gagnon, Denis L’Abbé, Alex Pelletier, Félix Malenfant, Maria Jaramillo, Maureen O’Connor-Mccourt, Cunle Wu, Yves Durocher, Mélanie Duchesne, Christine Gadoury, Anne Marcil, Yves Fortin, Beatrice Paul-Roc, Maurizio Acchione, Shawn C. Chafe, Oksana Nemirovsky, Joseph Lau, Francois Bénard, Shoukat Dedhar
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The architectural complexity and heterogeneity of the tumor microenvironment (TME) remains a substantial obstacle in the successful treatment of cancer. Hypoxia, caused by insufficient oxygen supply, and acidosis, resulting from the expulsion of acid
Externí odkaz:
https://doaj.org/article/a78bd5c3c72d4143937f4cd8eec87eef
Autor:
Joey G. Sheff, John F. Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L’Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar, Anne E.G. Lenferink
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Human carbonic anhydrase (hCAIX), an extracellular enzyme that catalyzes the reversible hydration of CO2, is often overexpressed in solid tumors. This enzyme is instrumental in maintaining the survival of cancer cells in a hypoxic and acidic tumor mi
Externí odkaz:
https://doaj.org/article/05ceb9ddaa0e4ba48f2d8c3227f954cc
Autor:
Traian Sulea, Nazanin Rohani, Jason Baardsnes, Christopher R. Corbeil, Christophe Deprez, Yuneivy Cepero-Donates, Alma Robert, Joseph D. Schrag, Marie Parat, Mélanie Duchesne, Maria L. Jaramillo, Enrico O. Purisima, John C. Zwaagstra
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Recent development of monoclonal antibodies as mainstream anticancer agents demands further optimization of their safety for use in humans. Potent targeting and/or effector activities on normal tissues is an obvious toxicity concern. Optimization of
Externí odkaz:
https://doaj.org/article/f7e7bbaa010a45d39cfc5376757156e7
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 238-244 (2016)
Within the research and development environment, higher throughput, parallelized protein purification is required for numerous activities, from small scale purification of monoclonal antibodies (mAbs) and antibody fragments for in vitro and in vivo a
Externí odkaz:
https://doaj.org/article/8eddef19fddd484499b55680d67b1a2a
Autor:
Simon Joubert, Julie Guimond, Sylvie Perret, Félix Malenfant, S. Mehdy Elahi, Anne Marcil, Marie Parat, Michel Gilbert, Anne E.G. Lenferink, Jason Baardsnes, Yves Durocher
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(8)
Some effector functions prompted by immunoglobulin G (IgG) antibodies, such as antibody-dependent cell-mediated cytotoxicity (ADCC), strongly depend on the N-glycans linked to asparagine 297 of the Fc region of the protein. A single α-(1,6)-fucosylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbc0e8efb2ac390c0b2c0711df7aa7a
https://pubmed.ncbi.nlm.nih.gov/35509261
https://pubmed.ncbi.nlm.nih.gov/35509261
Autor:
Cunle Wu, Yves Fortin, Andrea Acel, Marie Parat, Denis L'Abbé, Mélanie Duchesne, Shawn C. Chafe, Jason Baardsnes, Shoukat Dedhar, Mylene Gosselin, John F. Kelly, Anna Robotham, Joey G. Sheff, Anne E.G. Lenferink, Henk van Faassen, Traian Sulea, Félix Malenfant, Paul C. McDonald, Shannon Awrey, Jean Lefebvre, Alex Pelletier
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Human carbonic anhydrase (hCAIX), an extracellular enzyme that catalyzes the reversible hydration of CO2, is often overexpressed in solid tumors. This enzyme is instrumental in maintaining the survival of cancer cells in a hypoxic and acidic tumor mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5fe5101105353d594f55bce98ca553
https://nrc-publications.canada.ca/eng/view/object/?id=b84f2488-1160-40b0-9ea8-e1ed0c1c57e9
https://nrc-publications.canada.ca/eng/view/object/?id=b84f2488-1160-40b0-9ea8-e1ed0c1c57e9
Autor:
Paul C. McDonald, Christiane Cantin, Hafida Oamari, Alma Robert, Alex Pelletier, Anne Marcil, Myriam Banville, Suzanne Grothe, Stevo Radinovic, Cunle Wu, Mélanie Duchesne, Francois Benard, Nathalie Bousquet-Gagnon, Andrea Acel, Marie Parat, Maurizio Acchione, Annie Dulude, Shoukat Dedhar, Joseph Lau, Maria L. Jaramillo, Maureen D. O'Connor-McCourt, Yves Durocher, Christine Gadoury, Yves Fortin, Beatrice Paul-Roc, Yuneivy Cepero-Donates, Denis L'Abbé, Jason Baardsnes, Félix Malenfant, Anne E.G. Lenferink, Mylene Gosselin, Mehul Patel, Patrick Salois, Martin Lafrance, Oksana Nemirovsky, Paul Lachance, Shawn C. Chafe
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The architectural complexity and heterogeneity of the tumor microenvironment (TME) remains a substantial obstacle in the successful treatment of cancer. Hypoxia, caused by insufficient oxygen supply, and acidosis, resulting from the expulsion of acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490ba9b15ff09e7944d25cf4f097acfc
https://doi.org/10.1080/19420862.2021.1999194
https://doi.org/10.1080/19420862.2021.1999194
Autor:
Yuneivy Cepero-Donates, Maria L. Jaramillo, Nazanin Rohani, Marie Parat, Joseph D. Schrag, Christophe Deprez, Christopher R. Corbeil, Alma Robert, Jason Baardsnes, Traian Sulea, Mélanie Duchesne, Enrico O. Purisima, John C. Zwaagstra
Publikováno v:
mAbs
Recent development of monoclonal antibodies as mainstream anticancer agents demands further optimization of their safety for use in humans. Potent targeting and/or effector activities on normal tissues is an obvious toxicity concern. Optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a669f3e9903baa91ccd54cdf4304f7d
https://doi.org/10.1080/19420862.2019.1682866
https://doi.org/10.1080/19420862.2019.1682866
Autor:
Danica Stanimirovic, Alexandra T. Star, Nathan Yoganathan, Pedro Rosa-Neto, Balu Chakravarthy, Marguerite Ball, Michel Ménard, Alex Pelletier, James F. Whitfield, Christie Delaney, Kerry Rennie, Eric Grazzini, Susan Jiang, Trevor Atkinson, Leslie Brown, Eric Brunette, Martin N. Perkins, Arsalan S. Haqqani, Etienne Lessard, Wen Ding, Yves Durocher, Marie Parat, Ewa Baumann, Michael Waterston
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa61338d65a3d5c264b7ca79df8168d
https://doi.org/10.1016/j.jalz.2017.06.703
https://doi.org/10.1016/j.jalz.2017.06.703