Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie Oliver Metzig"'
Autor:
Marie Oliver Metzig, Ying Tang, Simon Mitchell, Brooks Taylor, Robert Foreman, Roy Wollman, Alexander Hoffmann
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-17 (2020)
Abstract Balancing cell death is essential to maintain healthy tissue homeostasis and prevent disease. Tumor necrosis factor (TNF) not only activates nuclear factor κB (NFκB), which coordinates the cellular response to inflammation, but may also tr
Externí odkaz:
https://doaj.org/article/ab58075b2e154f22b2042b859c9f099a
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 974 (2022)
Over several decades, cell biology research has characterized distinct forms of regulated cell death, identified master regulators such as nuclear factor kappa B (NFκB), and contributed to translating these findings in order to improve anti-cancer t
Externí odkaz:
https://doaj.org/article/9480c6085a814052a1aa1af3aff39d87
Autor:
Geena V. Ildefonso, Marie Oliver Metzig, Alexander Hoffmann, Leonard A. Harris, Carlos F. Lopez
Publikováno v:
Biophysical Journal. 122:817-834
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda5dce1766b538e407ff530816aaece
https://doi.org/10.1016/j.bpj.2023.01.035
https://doi.org/10.1016/j.bpj.2023.01.035
Autor:
Tiemo Sven Gerber, Dirk Andreas Ridder, Alexander Brobeil, Benjamin Goeppert, Philipp Stenzel, Elena Lippe, Stefanie Zimmer, Jörg Jäkel, Marie Oliver Metzig, Roxana Schwab, Steve Zacharias Martin, Peter R. Galle, Hauke Lang, Wilfried Roth, Beate Katharina Straub
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb1f71547d28ba4743504b56059094d
https://doi.org/10.1055/s-0042-1759996
https://doi.org/10.1055/s-0042-1759996
Autor:
Geena V. Ildefonso, Marie Oliver-Metzig, Alexander Hoffmann, Leonard A. Harris, Carlos F. Lopez
Necroptosis is a form of regulated cell death that has been associated with degenerative disorders, autoimmune processes, inflammatory diseases, and cancer. To better understand the biochemical mechanisms of necroptosis cell death regulation, we cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::580852f3f016fc050ab3a2e80b05477e
https://doi.org/10.1101/2022.02.25.481705
https://doi.org/10.1101/2022.02.25.481705
Autor:
Marie Oliver Metzig, Parthiv Patel, Hsiung-Lin Tu, Andrew Wang, Savaş Tay, Kabir Husain, Alexander Hoffmann, Arvind Murugan, Jing Lin, Minjun Son
Publikováno v:
Science Signaling, vol 14, iss 666
Sci Signal
Sci Signal
Cells receive a wide range of dynamic signaling inputs during immune regulation, but how gene regulatory networks measure such dynamic inputs is not well understood. Here, we used microfluidic single-cell analysis and mathematical modeling to study h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a4d07af3ee74d12da3ad8123347334
https://escholarship.org/uc/item/2gk837hk
https://escholarship.org/uc/item/2gk837hk
Autor:
Robert Foreman, Ying Tang, Simon Mitchell, Marie Oliver Metzig, Roy Wollman, Brooks Taylor, Alexander Hoffmann
Publikováno v:
Molecular systems biology, vol 16, iss 12
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Molecular Systems Biology
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Molecular Systems Biology
Balancing cell death is essential to maintain healthy tissue homeostasis and prevent disease. Tumor necrosis factor (TNF) not only activates nuclear factor κB (NFκB), which coordinates the cellular response to inflammation, but may also trigger nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ee8c4100c16e7c39996e6eb9008589
https://doi.org/10.15252/msb.20209677
https://doi.org/10.15252/msb.20209677
Autor:
Alexander Hoffmann, Minjun Son, Arvind Murugan, Kabir Husain, Savaş Tay, Hsiung-Lin Tu, Parthiv Patel, Jing Lin, Andrew Wang, Marie Oliver Metzig
Cells receive a wide range of dynamic signaling inputs during immune regulation, but how gene regulatory networks measure and interpret such dynamic inputs is not understood. Here, we used microfluidic live-cell analysis and mathematical modeling to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd670bd9ddaf14443830399f36190f88
https://doi.org/10.1101/752394
https://doi.org/10.1101/752394
Autor:
Koushik Roy, Alexander Hoffmann, Sho Ohta, Stephen L. Nutt, Yi Liu, Marie Oliver Metzig, Yu-sheng Lin, Simon Mitchell
Publikováno v:
Immunity, vol 50, iss 3
Humoral immunity depends on efficient activation of B-cells and their subsequent differentiation to antibody secreting cells (ASCs). The transcription factor NFκB cRel is critical for B-cell proliferation, but incorporating its known regulatory inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52012983a95fa3dba85f6f248c5f55f8
https://doi.org/10.1016/j.immuni.2019.02.004
https://doi.org/10.1016/j.immuni.2019.02.004
Publikováno v:
Cancer Research. 78:2326-2326
Resistance to regulated cell death (RCD) is an important hallmark of cancer and reason why chemotherapy fails. Efficient reprogramming of cancer cells requires a molecular and dynamic understanding of regulatory circuits. Research has uncovered sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b172d82ac5d3608e4da91b462327eec0
https://doi.org/10.1158/1538-7445.am2018-2326
https://doi.org/10.1158/1538-7445.am2018-2326