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pro vyhledávání: '"Marie Nadai"'
Publikováno v:
Plant Physiology. 150:1474-1481
Genetically engineered chloroplasts have an extraordinary capacity to accumulate recombinant proteins. We have investigated in tobacco (Nicotiana tabacum) the possible consequences of such additional products on several parameters of plant developmen
Autor:
Manuel Dubald, Maxime Vitel, Julia Bally, Claudette Job, Johan Botterman, Marie Nadai, Ghislaine Tissot
Publikováno v:
Transgenic research. 18(2)
We have produced human alpha1-antitrypsin (A1AT), a major therapeutic protein, in genetically engineered tobacco plastids. Four different expression vectors have been evaluated which encode A1AT under the control of various 5′ and 3′ plastid expr
Publikováno v:
Plant biotechnology journal. 6(3)
Aprotinin, a bovine protease inhibitor of important therapeutic value, was expressed in tobacco plastid transformants. This disulphide bond-containing protein was targeted to the lumen of thylakoids using signal peptides derived from nuclear genes wh