Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marie Miglianico"'
Autor:
Marie Miglianico, Judith M. Bolscher, Martijn W. Vos, Karin J. M. Koolen, Marloes de Bruijni, Deeya S. Rajagopal, Emily Chen, Michael Kiczun, David Gray, Brice Campo, Robert W. Sauerwein, Koen J. Dechering
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A high-throughput screening pipeline tests the feasibility of targeting the sporozoite stage of P. falciparum through chemical interventions and identifies gramicidin as a potential sporontocidal agent.
Externí odkaz:
https://doaj.org/article/274c968724b1436f997a2540094cde1f
Autor:
Marta Tajes, Joost J. F. P. Luiken, Marie Miglianico, Emma Barroso, Ricardo Rodríguez-Calvo, Will A. Coumans, Dietbert Neumann, Jan F. C. Glatz, Manuel Vázquez-Carrera, Yvonne Oligschlaeger, Dipanjan Chanda
Publikováno v:
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1862(5), 541-551. Elsevier
Small heterodimer partner (SHP) is an atypical nuclear receptor expressed in heart that has been shown to inhibit the hypertrophic response. Here, we assessed the role of SHP in cardiac metabolism and inflammation. Mice fed a high-fat diet (HFD) disp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1835d5c25522b764ffd066d08d1a4dc
https://doi.org/10.1016/j.bbalip.2017.02.006
https://doi.org/10.1016/j.bbalip.2017.02.006
Autor:
Maria Adelaida Garcia-Gimeno, Joost J. F. P. Luiken, Marie Miglianico, Jan F. C. Glatz, Dietbert Neumann, Carla Rubio-Villena, Yilin Liu, Pascual Sanz, J. Willem Voncken, Vivian E. H. Dahlmans, Will A. Coumans, Yvonne Oligschlaeger, Dipanjan Chanda
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biochemical Journal, 473(7), 937-947. Portland Press Ltd.
instname
Biochemical Journal, 473(7), 937-947. Portland Press Ltd.
11 páginas, 7 figuras.
AMP-activated protein kinase (AMPK) is a metabolic stress-sensing kinase. We previously showed that glucose deprivation induces autophosphorylation of AMPKβ at threonine-148 (Thr-148), which prevents the binding of AMPK
AMP-activated protein kinase (AMPK) is a metabolic stress-sensing kinase. We previously showed that glucose deprivation induces autophosphorylation of AMPKβ at threonine-148 (Thr-148), which prevents the binding of AMPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232b0c0ccabadef54ef8b6cf9327c559
https://cris.maastrichtuniversity.nl/en/publications/54696041-acbf-476f-a224-d50fe00e4bbd
https://cris.maastrichtuniversity.nl/en/publications/54696041-acbf-476f-a224-d50fe00e4bbd
Publikováno v:
Journal of Medicinal Chemistry. 59:2879-2893
As a central regulator of metabolism, the AMP-activated protein kinase (AMPK) is an established therapeutic target for metabolic diseases. Beyond the metabolic area, the number of medical fields that involve AMPK grows continuously, expanding the pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4df84f217d61b65fdfac2b8a1e513ed
https://doi.org/10.1021/acs.jmedchem.5b01201
https://doi.org/10.1021/acs.jmedchem.5b01201
Autor:
Roland D. Tuerk, Marie Miglianico, Paul R. Gooley, Ramon F. Thali, Yvonne Oligschlaeger, Dipanjan Chanda, David I. Stapleton, Roland W. Scholz, Dietbert Neumann
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, 290 (18)
Journal of Biological Chemistry, 290(18), 11715-11728. American Society for Biochemistry and Molecular Biology, Inc.
Journal of Biological Chemistry, 290 (18)
Journal of Biological Chemistry, 290(18), 11715-11728. American Society for Biochemistry and Molecular Biology, Inc.
The mammalian AMP-activated protein kinase (AMPK) is an obligatory αβγ heterotrimeric complex carrying a carbohydrate-binding module (CBM) in the β-subunit (AMPKβ) capable of attaching AMPK to glycogen. Nonetheless, AMPK localizes at many differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09704db83d240032953738bcb322b59
http://europepmc.org/articles/PMC4416872
http://europepmc.org/articles/PMC4416872
Publikováno v:
Gestion. 44:110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bd560d15f608d81a15e2131594abaa4
https://doi.org/10.3917/riges.442.0110
https://doi.org/10.3917/riges.442.0110
Publikováno v:
Environmental Modeling & Assessment
Environmental Modeling & Assessment, Springer, 2016, 21 (3), pp.407-418. ⟨10.1007/s10666-015-9494-y⟩
Environmental Modeling & Assessment, 2016, 21 (3), pp.407-418. ⟨10.1007/s10666-015-9494-y⟩
Environmental Modeling & Assessment, Springer, 2016, 21 (3), pp.407-418. ⟨10.1007/s10666-015-9494-y⟩
Environmental Modeling & Assessment, 2016, 21 (3), pp.407-418. ⟨10.1007/s10666-015-9494-y⟩
Agricultural changes have caused severe decline in the common bird communities in Europe. Mitigating this loss requires both understanding of and way to predict how agriculture affects biodiversity. The objective of this paper is to test the differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add4a037ae0b2f5be9a66d1a79b33fc5
https://hal.archives-ouvertes.fr/hal-01531650
https://hal.archives-ouvertes.fr/hal-01531650
Autor:
I.W.M. Bleylevens, Yvonne Oligschläger, Gerry A. F. Nicolaes, Dipanjan Chanda, Marie Miglianico, Dietbert Neumann
Publikováno v:
Nederlands Tijdschrift voor Diabetologie. 11:151-151
The energy-sensor AMP-activated protein kinase (AMPK) cycles between a glycogen-bound and a free state. The muscle-specific regulatory AMPKβ2 subunit carries a high affinity carbohydrate-binding module (CBM). Upon energy stress, such as exercise, AM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5924b3bf5bbd3b601dcb18409231d418
https://doi.org/10.1007/s12467-013-0092-9
https://doi.org/10.1007/s12467-013-0092-9
Autor:
Roland Scholz, Dipanjan Chanda, Jan F.C. Glatz, Ramon F. Thali, Yvonne Oligschläger, Roland D. Türk, Marie Miglianico, Dietbert Neumann
Publikováno v:
Nederlands Tijdschrift voor Diabetologie. 11:150-150
Disposal of glucose into muscular glycogen is diminished in type 2 diabetes (T2D). In response to various cellular stress signals, AMP-activated protein kinase (AMPK; αβγ) affects key metabolic pathways to equilibrate energy intake and expenditure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315ed7209911959856537ee6299092c8
https://doi.org/10.1007/s12467-013-0090-y
https://doi.org/10.1007/s12467-013-0090-y