MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

Autor: Romina Aron Badin, Aurore Bugi, Susannah Williams, Marta Vadori, Marie Michael, Caroline Jan, Alberto Nassi, Sophie Lecourtois, Antoine Blancher, Emanuele Cozzi, Philippe Hantraye, Anselme L. Perrier

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Matching iPSC donors’ and patients’ HLA haplotypes has been proposed as a way to generate cell therapy products with enhanced immunological compatibility. Here the authors show that MHC matching alone is insufficient to grant long-term survival o

Externí odkaz: https://doaj.org/article/c38f707228a749deb5410c466af92cb5

NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

Autor: Drazic, Adrian, Aksnes, Henriette, Marie, Michaël, Boczkowska, Malgorzata, Varland, Sylvia, Timmerman, Evy, Foyn, Håvard, Glomnes, Nina, Rebowski, Grzegorz, Impens, Francis, Gevaert, Kris, Dominguez, Roberto, Arnesen, Thomas

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 Apr . 115(17), 4399-4404.

Externí odkaz: https://www.jstor.org/stable/26508649

2D and 3D Human Induced Pluripotent Stem Cell-Based Models to Dissect Primary Cilium Involvement during Neocortical Development

Autor: Sophie Thomas, Nathalie Lefort, Nadia Bahi-Buisson, Tania Attié-Bitach, Sophie Saunier, Corinne Lebreton, Sébastien Dupichaud, Cécile Deleschaux, Clémantine Dimartino, Camille Maillard, Nicolas Goudin, Julie Pernelle, Sarah Farcy, Damelys Calderon, Céline Banal, Marie Michael, Lucile Boutaud

Publikováno v: Journal of visualized experiments : JoVE
Journal of visualized experiments : JoVE, 2022, 181, ⟨10.3791/62667⟩

International audience; Primary cilia (PC) are non-motile dynamic microtubule-based organelles that protrude from the surface of most mammalian cells. They emerge from the older centriole during the G1/G0 phase of the cell cycle, while they disassemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245ac39164c77069705ec6ce13031b49
https://hal-univ-paris.archives-ouvertes.fr/hal-03690521

Emerging new roles of the pre-Golgi intermediate compartment in biosynthetic-secretory trafficking

Autor: Saraste, Jaakko, Dale, Hege A., Bazzocco, Sarah, Marie, Michaël

Publikováno v: In FEBS Letters 2009 583(23):3804-3810

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

Autor: Susannah Williams, Alberto Nassi, Philippe Hantraye, Aurore Bugi, Marie Michael, Sophie Lecourtois, Caroline Jan, Emanuele Cozzi, Antoine Blancher, Anselme L. Perrier, Romina Aron Badin, Marta Vadori

Publikováno v: Nature Communications
Nature Communications, In press, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Nature Publishing Group, 2019, 10, pp.4357. ⟨10.1038/s41467-019-12324-0⟩
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Cell therapy products (CTP) derived from pluripotent stem cells (iPSCs) may constitute a renewable, specifically differentiated source of cells to potentially cure patients with neurodegenerative disorders. However, the immunogenicity of CTP remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588ddf3c7a3ff145b06c0db45b983fe1
https://hal-cea.archives-ouvertes.fr/cea-02997553