High serum prevalence of autoreactive IgG antibodies against peripheral nerve structures in patients with neurological post-COVID-19 vaccination syndrome

Autor: Friederike A. Arlt, Ameli Breuer, Elli Trampenau, Fabian Boesl, Marieluise Kirchner, Philipp Mertins, Elisa Sánchez-Sendín, Mahoor Nasouti, Marie Mayrhofer, Martin Blüthner, Matthias Endres, Harald Prüss, Christiana Franke

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundPatients suffering from neurological symptoms after COVID-19 vaccination (post-COVID-19 vaccination syndrome (PCVS)) have imposed an increasing challenge on medical practice, as diagnostic precision and therapeutic options are lacking. Unde

Externí odkaz: https://doaj.org/article/47d2ff8a2f924647991d4a32aaccc67d

A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth

Autor: Pierre Affaticati, Pietro Luigi Poliani, Victor Gourain, Arnim Jenett, Marie Mayrhofer, Markus Reischl, Francesca Demichelis, Matteo Benelli, Dirk Sieger, Jean-Stéphane Joly, Marina Mione

Publikováno v: Disease Models and Mechanisms 1 (10), 15-28. (2017)
Disease models & mechanisms, 10, 15-28
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 10, Iss 1, Pp 15-28 (2017)
Disease Models & Mechanisms, Cambridge Company of Biologists, 2017, 10 (1), pp.15-28. ⟨10.1242/dmm.026500⟩
Mayrhofer, M, Gourain, V, Reischl, M, Affaticati, P, Jenett, A, Joly, J-S, Benelli, M, Demichelis, F, Poliani, P L, Sieger, D & Mione, M 2017, ' A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK-and PI3K-induced malignant growth ', Disease Models and Mechanisms, vol. 10, no. 1, pp. 15-28 . https://doi.org/10.1242/dmm.026500

Somatic mutations activating MAPK and PI3K signalling play a pivotal role in both tumours and brain developmental disorders. We developed a zebrafish model of brain tumours based on somatic expression of oncogenes that activate MAPK and PI3K signalli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb99aea5c5fb7fe76167b9f6dbcd112
http://hdl.handle.net/11572/173227

The Toolbox for Conditional Zebrafish Cancer Models

Autor: Marina Mione, Marie Mayrhofer

Publikováno v: Cancer and Zebrafish ISBN: 9783319306520

Here we describe the conditional zebrafish cancer toolbox, which allows for fine control of the expression of oncogenes or downregulation of tumor suppressors at the spatial and temporal level. Methods such as the Gal4/UAS or the Cre/lox systems pave

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4251dd0dc44128cac153982af781c21b
https://doi.org/10.1007/978-3-319-30654-4_2