Výsledky vyhledávání - "Marie Marthe Krady"

Akademický článek

Cancer immunotherapy with enveloped self-amplifying mRNA CARG-2020 that modulates IL-12, IL-17 and PD-L1 pathways to prevent tumor recurrence

Autor: Ju Chen, Bhaskara Reddy Madina, Elham Ahmadi, Timur Olegovich Yarovinsky, Marie Marthe Krady, Eileen Victoria Meehan, Isabella China Wang, Xiaoyang Ye, Elise Pitmon, Xian-Yong Ma, Bijan Almassian, Valerian Nakaar, Kepeng Wang

Publikováno v: Acta Pharmaceutica Sinica B, Vol 14, Iss 1, Pp 335-349 (2024)

Targeting multiple immune mechanisms may overcome therapy resistance and further improve cancer immunotherapy for humans. Here, we describe the application of virus-like vesicles (VLV) for delivery of three immunomodulators alone and in combination,

Externí odkaz: https://doaj.org/article/b149662df00f4fbebd93291fb982e6aa

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cAMP-dependent protein kinase phosphorylates and activates nuclear Ca 2+ -ATPase

Autor: Patrick Rogue, Alphonse Meyer, Jean-Paul Humbert, Anant N. Malviya, Solange Freyermuth, Marie-Marthe Krady

Publikováno v: Proceedings of the National Academy of Sciences. 95:9178-9183

A Ca 2+ -pump ATPase, similar to that in the endoplasmic reticulum, has been located on the outer membrane of rat liver nuclei. The effect of cAMP-dependent protein kinase (PKA) on nuclear Ca 2+ -ATPase (NCA) was studied by using purified rat liver n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446de2a53bd554ab3c476b9567594a93
https://doi.org/10.1073/pnas.95.16.9178

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Pervanadate elicits proliferation and mediates activation of mitogen-activated protein (MAP) kinase in the nucleus1

Autor: Marie-Marthe Krady, Patrick Rogue, Solange Freyermuth, Anant N. Malviya

Publikováno v: FEBS Letters. 412:420-424

There is growing evidence for the role of protein tyrosine phosphatases in controlling such fundamental cellular processes as growth and differentiation. Pervanadate is a potent inhibitor of protein tyrosine phosphatase which has been observed here t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3749da43911f8e99ca008640a31ea411
https://doi.org/10.1016/s0014-5793(97)00821-1

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Foreign Body Giant Cell Formation Is Preceded by Lamellipodia Formation and Can Be Attenuated by Inhibition of Rac1 Activation

Autor: Marie-Marthe Krady, Farah Laiwalla, Eleni A. Skokos, Themis R. Kyriakides, Steven M. Jay

Macrophages that are recruited to the site of implanted biomaterials undergo fusion to form surface-damaging foreign body giant cells. Exposure of peripheral blood monocytes to interleukin-4 can recapitulate the fusion process in vitro. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a922c27b588b6c9752917ce44e2dd7
https://europepmc.org/articles/PMC1934537/

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Pervanadate-triggered MAP kinase activation and cell proliferation are not sensitive to PD 98059 Evidence for stimulus-dependent differential PD 98059 inhibition mechanism

Autor: Marie-Marthe Krady, Anant N. Malviya, Jean-Luc Dupont

Publikováno v: FEBS Letters. (3):241-244

A tight and stable complex with corresponding protein kinases and phosphatases establishes coupling between activators and inactivators. One such example is emerging from the studies of the Ras-dependent MAP kinase cascade signaling pathway. Pervanad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33d86fa5de1ae5bf5bda96a6325b48e

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