The unfolded protein response in a dolichyl phosphate mannose-deficient Chinese hamster ovary cell line points out the key role of a demannosylation step in the quality-control mechanism of N-glycoproteins

Autor: Foulquier, Francois, Harduin-Lepers, Anne, Duvet, Sandrine, Marchal, Ingrid, Marie MIR, Anne, Delannoy, Philippe, Chirat, Frédéric, Cacan, René

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2002, 362 (Pt 2), pp.491-8
Biochemical Journal, Portland Press, 2002, 362 (2), pp.491. ⟨10.1042/0264-6021:3620491⟩
Biochemical Journal, 2002, 362 (Pt 2), pp.491-8
Biochemical Journal, 2002, 362 (2), pp.491. ⟨10.1042/0264-6021:3620491⟩

International audience; The CHO (Chinese hamster ovary) glycosylation mutant cell line, B3F7, transfers the truncated glycan Glc(3)Man(5)GlcNAc(2) on to nascent proteins. After deglucosylation, the resulting Man(5)GlcNAc(2) glycan is subjected to two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9beecf28c460d65c9126de2cc21bf7d
https://hal.archives-ouvertes.fr/hal-01224175