Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marie M. Holahan"'
Autor:
Mark E. Duggan, Jeffrey S. Barrett, Joan D. Ellis, Joseph J. Lynch, Ofir A. Moreno, Nathan C. Ihle, Robert J. Gould, George D. Hartman, Theoharides Anthony D, Marie M. Holahan, Maria T. Stranieri
Publikováno v:
Pharmaceutical Research. 11:426-431
The pharmacokinetics and pharmacodynamics of L-703,014, a fibrinogen receptor antagonist, have been examined in the dog. An analytical method which utilizes methanol precipitation of dog plasma proteins followed by HPLC with an automated column switc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9948830cbd05db4acaec4a003388a5d0
https://doi.org/10.1023/a:1018973323039
https://doi.org/10.1023/a:1018973323039
Autor:
Li W; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Wang Y; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Lohith TG; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Zeng Z; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Tong L; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Mazzola R; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Riffel K; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Miller P; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Purcell M; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Holahan M; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Haley H; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Gantert L; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Hesk D; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Ren S; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Morrow J; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Uslaner J; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Struyk A; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Wai JM; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Rudd MT; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Tellers DM; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., McAvoy T; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Bormans G; Laboratory for Radiopharmaceutical Research, KU Leuven, 3001 Leuven, Belgium., Koole M; Nuclear Medicine and Molecular Imaging, KU Leuven and University Hospital Leuven, 3001 Leuven, Belgium., Van Laere K; Nuclear Medicine and Molecular Imaging, KU Leuven and University Hospital Leuven, 3001 Leuven, Belgium., Serdons K; Nuclear Medicine and Molecular Imaging, KU Leuven and University Hospital Leuven, 3001 Leuven, Belgium., de Hoon J; Center for Clinical Pharmacology, KU Leuven, 3001 Leuven, Belgium., Declercq R; Translational Pharmacology Europe, MSD (Europe) Inc., 1200 Brussels, Belgium., De Lepeleire I; Translational Pharmacology Europe, MSD (Europe) Inc., 1200 Brussels, Belgium., Pascual MB; Nantz National Alzheimer Center, Houston Methodist Neurological Institute, Houston, TX 77030, USA.; Department of Neurology, Weill Cornell Medicine, New York, NY 10065, USA., Zanotti-Fregonara P; Nantz National Alzheimer Center, Houston Methodist Neurological Institute, Houston, TX 77030, USA.; Department of Neurology, Weill Cornell Medicine, New York, NY 10065, USA., Yu M; Nantz National Alzheimer Center, Houston Methodist Neurological Institute, Houston, TX 77030, USA.; Department of Neurology, Weill Cornell Medicine, New York, NY 10065, USA., Arbones V; Nantz National Alzheimer Center, Houston Methodist Neurological Institute, Houston, TX 77030, USA., Masdeu JC; Nantz National Alzheimer Center, Houston Methodist Neurological Institute, Houston, TX 77030, USA.; Department of Neurology, Weill Cornell Medicine, New York, NY 10065, USA., Cheng A; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Hussain A; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Bueters T; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Anderson MS; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Hostetler ED; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA., Basile AS; MRL, Merck & Co. Inc., Kenilworth, NJ 07033, USA.
Publikováno v:
Science translational medicine [Sci Transl Med] 2022 Jan 12; Vol. 14 (627), pp. eabg3684. Date of Electronic Publication: 2022 Jan 12.
Autor:
Li W; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA. wenping_li@merck.com., Wang Y; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Rubins D; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Bennacef I; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Holahan M; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Haley H; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Purcell M; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Gantert L; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Hseih S; PPDM Bioanalysis, MRL South San Francisco, 213 East Grand Blvd, South San Francisco, CA, 94080, USA., Judo M; PPDM Bioanalysis, MRL South San Francisco, 213 East Grand Blvd, South San Francisco, CA, 94080, USA., Seghezzi W; PPDM Bioanalysis, MRL South San Francisco, 213 East Grand Blvd, South San Francisco, CA, 94080, USA., Zhang S; PPDM Bioanalysis, MRL South San Francisco, 213 East Grand Blvd, South San Francisco, CA, 94080, USA., van der Veen EL; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Lub-de Hooge MN; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., de Vries EGE; Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands., Evelhoch JL; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Klimas M; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA., Hostetler ED; Translational Biomarkers, Merck & Co., Inc., WP 44D, 770 Sumneytown Pike, West Point, PA, 19486, USA.
Publikováno v:
Molecular imaging and biology [Mol Imaging Biol] 2021 Apr; Vol. 23 (2), pp. 250-259. Date of Electronic Publication: 2020 Oct 26.
Autor:
Rubins DJ; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA. Daniel_rubins@merck.com., Meng X; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., McQuade P; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Klimas M; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Getty K; Screening and Protein Sciences Department, Merck & Co., Inc., West Point, PA, USA., Lin SA; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Connolly BM; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., O'Malley SS; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Haley H; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Purcell M; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Gantert L; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Holahan M; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Lindgren J; Affibody AB, Solna, Sweden., Eklund P; Affibody AB, Solna, Sweden., Ekblad C; Affibody AB, Solna, Sweden., Frejd FY; Affibody AB, Solna, Sweden.; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Hostetler ED; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., González Trotter DE; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA., Evelhoch JL; Translational Biomarkers Department, Merck & Co., Inc., West Point, PA, USA.
Publikováno v:
Molecular imaging and biology [Mol Imaging Biol] 2021 Apr; Vol. 23 (2), pp. 241-249. Date of Electronic Publication: 2020 Oct 23.
Autor:
Tong L; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Li W; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Lo MM; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Gao X; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Wai JM; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Rudd M; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Tellers D; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Joshi A; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Zeng Z; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Miller P; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Salinas C; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Riffel K; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Haley H; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Purcell M; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Holahan M; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Gantert L; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Schubert JW; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Jones K; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Mulhearn J; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Egbertson M; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Meng Z; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Hanney B; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Gomez R; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Harrison ST; Discovery Chemistry, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., McQuade P; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Bueters T; Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Uslaner J; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Morrow J; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Thomson F; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Kong J; Department of Process Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue Rahway, New Jersey 07065, United States., Liao J; Department of Process Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue Rahway, New Jersey 07065, United States., Selyutin O; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Bao J; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States., Hastings NB; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Agrawal S; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Magliaro BC; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Monsma FJ Jr; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Smith MD; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Risso S; Discovery Biology, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Hesk D; Department of Process Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue Rahway, New Jersey 07065, United States., Hostetler E; Translational Biomarkers, Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States., Mazzola R; Discovery Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Mar 12; Vol. 63 (5), pp. 2411-2425. Date of Electronic Publication: 2020 Mar 03.
Autor:
Hostetler ED; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania eric.hostetler@merck.com., Walji AM; Discovery Chemistry, Merck & Co., Inc., West Point, Pennsylvania., Zeng Z; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Miller P; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Bennacef I; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Salinas C; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Connolly B; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Gantert L; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Haley H; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Holahan M; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Purcell M; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Riffel K; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Lohith TG; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania., Coleman P; Discovery Chemistry, Merck & Co., Inc., West Point, Pennsylvania., Soriano A; Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey., Ogawa A; Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey., Xu S; Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey., Zhang X; Pharmacology, Merck & Co., Inc., Kenilworth, New Jersey., Joshi E; Drug Metabolism, Merck & Co., Inc., West Point, Pennsylvania., Della Rocca J; Discovery Pharmaceutical Sciences, Merck & Co., Inc., West Point, Pennsylvania; and., Hesk D; Labelled Compound Synthesis, Merck & Co., Inc., Rahway, New Jersey., Schenk DJ; Labelled Compound Synthesis, Merck & Co., Inc., Rahway, New Jersey., Evelhoch JL; Translational Biomarkers, Merck & Co., Inc., West Point, Pennsylvania.
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2016 Oct; Vol. 57 (10), pp. 1599-1606. Date of Electronic Publication: 2016 May 26.
Autor:
Hostetler ED; Imaging, Merck & Co., Inc, West Point, PA, USA. eric.hostetler@merck.com., Fan H; Imaging, Merck & Co., Inc, West Point, PA, USA., Joshi AD; Imaging, Merck & Co., Inc, West Point, PA, USA., Zeng Z; Imaging, Merck & Co., Inc, West Point, PA, USA., Eng W; Imaging, Merck & Co., Inc, West Point, PA, USA., Gantert L; Imaging, Merck & Co., Inc, West Point, PA, USA., Holahan M; Imaging, Merck & Co., Inc, West Point, PA, USA., Meng X; Imaging, Merck & Co., Inc, West Point, PA, USA., Miller P; Imaging, Merck & Co., Inc, West Point, PA, USA., O'Malley S; Imaging, Merck & Co., Inc, West Point, PA, USA., Purcell M; Imaging, Merck & Co., Inc, West Point, PA, USA., Riffel K; Imaging, Merck & Co., Inc, West Point, PA, USA., Salinas C; Imaging, Merck & Co., Inc, West Point, PA, USA., Williams M; Imaging, Merck & Co., Inc, West Point, PA, USA., Ma B; Drug Metabolism, Merck & Co., Inc, West Point, PA, USA., Buist N; Pharmaceutical Sciences, Merck & Co., Inc, West Point, PA, USA., Smith SM; Neuroscience, Merck & Co., Inc, West Point, PA, USA., Coleman PJ; Discovery Chemistry, Merck & Co., Inc, West Point, PA, USA., Cox CD; Discovery Chemistry, Merck & Co., Inc, West Point, PA, USA., Flores BA; Discovery Chemistry, Merck & Co., Inc, West Point, PA, USA., Raheem IT; Discovery Chemistry, Merck & Co., Inc, West Point, PA, USA., Cook JJ; Imaging, Merck & Co., Inc, West Point, PA, USA., Evelhoch JL; Imaging, Merck & Co., Inc, West Point, PA, USA.
Publikováno v:
Molecular imaging and biology [Mol Imaging Biol] 2016 Aug; Vol. 18 (4), pp. 579-87.
Autor:
Walji AM; Discovery Chemistry, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Hostetler ED; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Selnick H; Discovery Chemistry, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Zeng Z; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Miller P; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Bennacef I; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Salinas C; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Connolly B; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Gantert L; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Holahan M; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., O'Malley S; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Purcell M; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Riffel K; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Li J; Process Chemistry, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Balsells J; Process Chemistry, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., OBrien JA; Pharmacology, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Melquist S; Pharmacology, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Soriano A; Pharmacology, Merck & Co., Inc. , Kenilworth, New Jersey 07033, United States., Zhang X; Pharmacology, Merck & Co., Inc. , Kenilworth, New Jersey 07033, United States., Ogawa A; Pharmacology, Merck & Co., Inc. , Kenilworth, New Jersey 07033, United States., Xu S; Pharmacology, Merck & Co., Inc. , Kenilworth, New Jersey 07033, United States., Joshi E; Drug Metabolism, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Della Rocca J; Discovery Pharmaceutical Sciences, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Hess FJ; Neuroscience, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Schachter J; Neuroscience, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Hesk D; Labelled Compound Synthesis, Merck & Co., Inc. , Rahway, New Jersey, 07065, United States., Schenk D; Labelled Compound Synthesis, Merck & Co., Inc. , Rahway, New Jersey, 07065, United States., Struyk A; Clinical Pharmacology, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Babaoglu K; Computational Chemistry, Merck & Co., Inc. , West Point, Pennsylvania 19486, United States., Lohith TG; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Wang Y; Pharmaron Beijing Co., Ltd. , Beijing 100176, China., Yang K; Pharmaron Beijing Co., Ltd. , Beijing 100176, China., Fu J; Pharmaron Beijing Co., Ltd. , Beijing 100176, China., Evelhoch JL; Imaging, Merck & Co., Inc. , West Point Pennsylvania 19486, United States., Coleman PJ; Discovery Chemistry, Merck & Co., Inc. , West Point Pennsylvania 19486, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 May 26; Vol. 59 (10), pp. 4778-89. Date of Electronic Publication: 2016 May 05.
Autor:
Stachel SJ, Zerbinatti C, Rudd MT, Cosden M, Suon S, Nanda KK, Wessner K, DiMuzio J, Maxwell J, Wu Z, Uslaner JM, Michener MS, Szczerba P, Brnardic E, Rada V, Kim Y, Meissner R, Wuelfing P, Yuan Y, Ballard J, Holahan M, Klein DJ, Lu J, Fradera X, Parthasarathy G, Uebele VN, Chen Z; WuXi AppTec Company, Ltd. , Shanghai 200131, P. R. China., Li Y; WuXi AppTec Company, Ltd. , Shanghai 200131, P. R. China., Li J; WuXi AppTec Company, Ltd. , Shanghai 200131, P. R. China., Cooke AJ, Bennett DJ, Bilodeau MT, Renger J
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2016 Apr 14; Vol. 59 (7), pp. 3489-98. Date of Electronic Publication: 2016 Apr 01.
Autor:
Egbertson M; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA. Electronic address: melissaegbertson@gmail.com., McGaughey GB; Structural Chemistry, WP53-3 Merck and Co., West Point, PA 19486, USA., Pitzenberger SM; NMR Structure Elucidation, Process and Analytical Chemistry, WP14-1 Merck and Co., West Point, PA 19486, USA., Stauffer SR; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Coburn CA; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Stachel SJ; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Yang W; Sunesis Pharmaceuticals, 395 Oyster Point Blvd. Ste. 400, South San Francisco, CA 94080, USA., Barrow JC; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Neilson LA; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., McWherter M; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Perlow D; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Fahr B; Sunesis Pharmaceuticals, 395 Oyster Point Blvd. Ste. 400, South San Francisco, CA 94080, USA., Munshi S; Structural Biology, WP 14-2 Merck and Co., West Point, PA 19486, USA., Allison TJ; Structural Biology, WP 14-2 Merck and Co., West Point, PA 19486, USA. Electronic address: timothy.j.allison@gmail.com., Holloway K; Structural Chemistry, WP53-3 Merck and Co., West Point, PA 19486, USA., Selnick HG; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA. Electronic address: selnickh@gmail.com., Yang Z; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Swestock J; Process Chemistry, WP 14-1 Merck and Co., West Point, PA 19486, USA., Simon AJ; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Sankaranarayanan S; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Colussi D; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Tugusheva K; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Lai MT; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Pietrak B; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Haugabook S; Pharmacology, WP 26-1 Merck and Co., West Point, PA 19486, USA., Jin L; Drug Metabolism, WP 75-B Merck and Co., West Point, PA 19486, USA., Chen IW; Drug Metabolism, WP 75-B Merck and Co., West Point, PA 19486, USA., Holahan M; Imaging Research, WP 44c Merck and Co., West Point, PA 19486, USA., Stranieri-Michener M; Imaging Research, WP 44c Merck and Co., West Point, PA 19486, USA., Cook JJ; Imaging Research, WP 44c Merck and Co., West Point, PA 19486, USA., Vacca J; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA., Graham SL; Medicinal Chemistry Department, WP14-2 Merck and Co., West Point, PA 19486, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Nov 01; Vol. 25 (21), pp. 4812-4819. Date of Electronic Publication: 2015 Jun 29.