Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Marie Luise Rao"'
Autor:
Dieter Lütjohann, Andreas Papassotiropoulos, Ingemar Björkhem, Sandra Locatelli, Metin Bagli, Randi D. Oehring, Uwe Schlegel, Frank Jessen, Marie Luise Rao, Klaus von Bergmann, Reinhard Heun
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 195-198 (2000)
Alzheimer's disease (AD) is characterized by the presence of senile plaques, neurofibrillary tangles, and neuronal cell loss associated with membrane cholesterol release. 24S-hydroxycholesterol (24S-OH-Chol) is an enzymatically oxidized product of ch
Externí odkaz:
https://doaj.org/article/f2b31f8cafbc43a0ab98d38c33becdad
Autor:
Marie Luise Rao, Olrik von Widdern, Astrid Zobel, Marcella Rietschel, Ulrich Jaehde, A. Dragicevic, Wolfgang Maier, Christoph Hiemke, K Grasmäder, Kai-Uwe Kühn, Petra Louise Verwohlt
Publikováno v:
European Journal of Clinical Pharmacology. 60:473-480
Mirtazapine belongs to the new generation of antidepressants that is commonly used in clinical routine. Therefore, we feel it mandatory to control compliance in the context of non-response, adverse events or other clinical situations by means of plas
Autor:
Marie Luise Rao, Christian Spell, Wolfgang Maier, Reinhard Heun, Frank Hentschel, Klaus von Bergmann, Anja Kerksiek, Dieter Lütjohann, Heike Kölsch, Marinella Damian
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 18:245-249
Sterol regulatory element-binding proteins (SREBPs) are transcription factors involved in cholesterol and fatty acid synthesis. Recently, a polymorphism in the 5′-region of the SREBP-1a gene has been described to be correlated with alterations in t
Autor:
Wolfgang Maier, Reinhard Heun, Ursula Ptok, Ralf G.M. Schlösser, Marie Luise Rao, Heike Kölsch, S. Brune, A. Schulz, Michael Majores
Publikováno v:
Journal of Neural Transmission. 110:1041-1050
The peroxisome proliferator-activated receptor alpha (PPAR-alpha) is a member of the steroid hormone super family of ligand-inducible transcription factors, involved in glucose and lipid metabolism. We screened for polymorphisms in the PPAR-alpha gen
Publikováno v:
Journal of Chromatography B. 794:35-47
Therapeutic drug monitoring necessitates efficient, fast and reliable analytical methods validated by external quality control. We therefore devised an isocratic reversed-phase HPLC method with ultraviolet detection and optimised this to quantify mir
Autor:
Reinhard Heun, Chartika M Kirschling, Marie Luise Rao, Heike Kölsch, Wolfgang Maier, Christine Frahnert
Publikováno v:
NeuroReport. 14:1243-1246
Pathological characteristics of Alzheimer's disease (AD) are neurofibrillary tangles and amyloid-beta (Abeta) plaques. Abeta is generated by cleavage of the amyloid precursor protein by beta- and gamma-secretases. BACE (beta-site APP cleaving enzyme)
Autor:
Karin Becker, Katharina Bürger, Wolfgang Maier, Frank Jessen, Andreas Papassotiropoulos, Reinhard Heun, Hans-Jürgen Möller, Metin Bagli, Marie Luise Rao, Ursula Ptok, Harald Hampel
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience. 253:44-48
Interleukin-6 (IL-6) is a multifunctional cytokine involved in the pathogenesis of Alzheimer's disease (AD). The effects of IL-6 are mediated through a specific receptor complex made up of a ligand binding glycoprotein (gp80 or IL-6R) and a signal tr
Autor:
Dieter Lütjohann, Wolfgang Maier, Frank Jessen, Reinhard Heun, Michael Ludwig, Marie Luise Rao, A Schulte, K. von Bergmann, Heike Kölsch, Ursula Ptok
Publikováno v:
Molecular Psychiatry. 7:899-902
Cholesterol and 24S-hydroxycholesterol are involved in the pathogenesis of Alzheimer's disease (AD). Increased serum cholesterol concentrations have been detected in patients with AD. 24S-Hydroxycholesterol is the primary cholesterol elimination prod
Autor:
Dagmar von Bubnoff, Heike Matz, Christine Frahnert, Marie Luise Rao, Daniel Hanau, Henri de la Salle, Thomas Bieber
Publikováno v:
The Journal of Immunology. 169:1810-1816
FcεRI is suspected to play a pivotal role in the pathophysiology of atopic disorders such as atopic dermatitis. In search for genes differentially regulated by FcεRI on APCs, a differential cDNA bank of receptor-stimulated and unstimulated monocyte
Autor:
Beatriz Rodriguez De La Torre, Berndt Lüderitz, Metin Bagli, Heyder Omran, Jan Dreher, Martin Kolbinger, Marie Luise Rao, Iaroslav Malevany
Publikováno v:
Therapeutic Drug Monitoring. 23:435-440
Tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) are used to treat depression. Whereas cardiovascular effects have occasionally been reported during controlled studies with SSRIs, TCA treatment poses a well-known p