Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Marie Line Andreola"'
Autor:
Marie-Line Andreola, Fréderic Becquart, Wahbi Jomaa, Paul O Verhoeven, Gérard Baldacchino, Simon Hemour, D-Mask consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0255148 (2021)
The widespread use of facemasks throughout the population is recommended by the WHO to reduce transmission of the SARS-CoV-2 virus. As some regions of the world are facing mask shortages, reuse may be necessary. However, used masks are considered as
Externí odkaz:
https://doaj.org/article/f69068942fe9420486d357372efa2899
Autor:
Chloé Jaubert, Amina Bedrat, Laura Bartolucci, Carmelo Di Primo, Michel Ventura, Jean-Louis Mergny, Samir Amrane, Marie-Line Andreola
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract DNA and RNA guanine-rich oligonucleotides can form non-canonical structures called G-quadruplexes or “G4” that are based on the stacking of G-quartets. The role of DNA and RNA G4 is documented in eukaryotic cells and in pathogens such as
Externí odkaz:
https://doaj.org/article/748f46532b7141e4bbf232f943511c9d
Autor:
Ferdinand Emaniel Brel Got, Patricia Recordon-Pinson, Ghislain Loubano-Voumbi, Dagene Ebourombi, Marie-Lise Blondot, Mathieu Metifiot, Gontran Ondzotto, Marie-Line Andreola
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2355 (2021)
Background: HIV infects around one hundred thousand patients in the Republic of the Congo. Approximately 25% of them receive an antiretroviral treatment; current first-line regimens include two NRTIs and one NNRTI, reverse transcriptase inhibitors. R
Externí odkaz:
https://doaj.org/article/d182430eeec342d79337e611664cf62a
Autor:
Chloé Torres, Asja Garling, Saïd Taouji, Christina Calmels, Marie-Line Andreola, Mathieu Métifiot
Publikováno v:
Molecules, Vol 26, Iss 17, p 5423 (2021)
Multiple viral targets are now available in the clinic to fight HIV infection. Even if this targeted therapy is highly effective at suppressing viral replication, caregivers are facing growing therapeutic failures in patients due to resistance, with
Externí odkaz:
https://doaj.org/article/ee205c82514f4ab9869b13e2b16737d7
Autor:
Mohamed S. Benleulmi, Julien Matysiak, Xavier Robert, Csaba Miskey, Eric Mauro, Delphine Lapaillerie, Paul Lesbats, Stéphane Chaignepain, Daniel R. Henriquez, Christina Calmels, Oyindamola Oladosu, Eloïse Thierry, Oscar Leon, Marc Lavigne, Marie-Line Andreola, Olivier Delelis, Zoltán Ivics, Marc Ruff, Patrice Gouet, Vincent Parissi
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase·viral DNA complex) and the nucleosome. The data from the literature suggest that direct protein
Externí odkaz:
https://doaj.org/article/62671881f03f4030ac954009c672ddde
Autor:
Julien Matysiak, Paul Lesbats, Eric Mauro, Delphine Lapaillerie, Jean-William Dupuy, Angelica P. Lopez, Mohamed Salah Benleulmi, Christina Calmels, Marie-Line Andreola, Marc Ruff, Manuel Llano, Olivier Delelis, Marc Lavigne, Vincent Parissi
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-20 (2017)
Abstract Background Insertion of retroviral genome DNA occurs in the chromatin of the host cell. This step is modulated by chromatin structure as nucleosomes compaction was shown to prevent HIV-1 integration and chromatin remodeling has been reported
Externí odkaz:
https://doaj.org/article/f1a02097fd57468eb90eecfd6d8494e1
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Mosquito- and tick-borne pathogens including Chikungunya, Dengue, Japanese encephalitis, West Nile, Yellow fever and Zika virus, represent a new economic and public health challenge. In the absence of effective vaccines and specific therapie
Externí odkaz:
https://doaj.org/article/5d7e140debe44068a932d7d7642b5a5f
Publikováno v:
Biochimie
Biochimie, 2021, ⟨10.1016/j.biochi.2021.11.003⟩
Biochimie, 2021, ⟨10.1016/j.biochi.2021.11.003⟩
As ZIKV continues to spread, many “unknowns” remain and research is needed to advance the understanding of this important pathogen. Viral RNA dependent-RNA polymerases (RdRp) are validated targets for inhibitors of the replication of several viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6e3d81f29d83c71d3e02cf063bc9a5
https://doi.org/10.1016/j.biochi.2021.11.003
https://doi.org/10.1016/j.biochi.2021.11.003
Autor:
Nicole Grandi, Enzo Tramontano, Francesca Esposito, Davide Ialongo, Alessandro De Leo, Giorgio Amendola, Daniela De Vita, Antonella Messore, Valentina Noemi Madia, Marie-Line Andreola, Ettore Novellino, Mathieu Métifiot, Sandro Cosconati, Roberta Costi, Angela Corona, Roberto Di Santo, Valeria Tudino, Francesco Saccoliti, Luigi Scipione
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (12), pp.8579-8598. ⟨10.1021/acs.jmedchem.1c00535⟩
Journal of Medicinal Chemistry, American Chemical Society, 2021, 64 (12), pp.8579-8598. ⟨10.1021/acs.jmedchem.1c00535⟩
Novel anti-HIV agents are still needed to overcome resistance issues, in particular inhibitors acting against novel viral targets. The ribonuclease H (RNase H) function of the reverse transcriptase (RT) represents a validated and promising target, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7119c7f6ddd81a9fee5dea8606a4e7
https://doi.org/10.1021/acs.jmedchem.1c00535
https://doi.org/10.1021/acs.jmedchem.1c00535
Autor:
Guillaume Beucher, Marie-Lise Blondot, Alexis Celle, Noémie Pied, Patricia Recordon-Pinson, Pauline Esteves, Muriel Faure, Mathieu Métifiot, Sabrina Lacomme, Denis Dacheux, Derrick R. Robinson, Gernot Längst, Fabien Beaufils, Marie-Edith Lafon, Patrick Berger, Marc Landry, Denis Malvy, Thomas Trian, Marie-Line Andreola, Harald Wodrich
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (28), ⟨10.1073/pnas.2202370119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (28), ⟨10.1073/pnas.2202370119⟩
International audience; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections initiate in the bronchi of the upper respiratory tract and are able to disseminate to the lower respiratory tract, where infections can cause an acute res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0d2eef99823f2ac361a27dc432c3a3
https://doi.org/10.1073/pnas.2202370119
https://doi.org/10.1073/pnas.2202370119