Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Marie Le Bouteiller"'
2
Precise and broad scope genome editing based on high-specificity Cas9 nickases
Autor: Jin Liu, Manuel A F V Gonçalves, Richard L. Frock, Marie Le Bouteiller, Qian Wang, Josephine M. Janssen
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 49(2), 1173-1198. OXFORD UNIV PRESS
RNA-guided nucleases (RGNs) based on CRISPR systems permit installing short and large edits within eukaryotic genomes. However, precise genome editing is often hindered due to nuclease off-target activities and the multiple-copy character of the vast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abdc871f6974ca50abd72a4d87c1bbe
http://europepmc.org/articles/PMC7826261
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3
Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation
Autor: Pawel J. Schweiger, Marie Le Bouteiller, Shiro Yui, Malte Thodberg, Ditte Clement, Kim B. Jensen
Publikováno v: Schweiger, P J, Le Bouteiller, M, Yui, S, Thodberg, M, Clement, D & Jensen, K B 2022, ' Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation ', Gastroenterology, vol. 163, no. 6, pp. 1688-1690.e3 . https://doi.org/10.1053/j.gastro.2022.08.036
Gastroenterology
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fcee4a7ced8fd7815a1fe907a51baa
https://curis.ku.dk/portal/da/publications/extracellular-matrix-interactions-provide-tumor-cells-with-an-escape-mechanism-for-commitment-to-differentiation(b527271c-8f1d-4a70-9c2a-4c9e79640c38).html
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4
Ku70 suppresses alternative end joining in G1-arrested progenitor B cells
Autor: Richard L. Frock, Frederick W. Alt, Jeffrey Zurita, Vipul Kumar, Sherry G. Lin, Jiangman Lou, Josefin Kenrick, Cristian Boboila, Adam Yongxin Ye, Marie Le Bouteiller, Jianqiao Hu, Zhuoyi Liang
Publikováno v: Proc Natl Acad Sci U S A
Classical nonhomologous end joining (C-NHEJ) repairs DNA double-strand breaks (DSBs) throughout interphase but predominates in G1 phase when homologous recombination is unavailable. Complexes containing the Ku70/80 (“Ku”) and XRCC4/ligase IV (Lig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6075287bd3340bd8e7d039986af43f
https://doi.org/10.1073/pnas.2103630118
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5
Mouse adult hematopoietic stem cells actively synthetize ribosomal RNA
Autor: Ana Cumano, Alexandre David, Sandrine Vandormael-Pournin, Sabrina Coqueran, Michel Cohen-Tannoudji, Marie Le Bouteiller, Aurélien Raveux, Léonard Jarzebowski
Publikováno v: RNA
RNA, 2018, 24 (12), pp.1803-1812. ⟨10.1261/rna.067843.118⟩
RNA, Cold Spring Harbor Laboratory Press, 2018, 24 (12), pp.1803-1812. ⟨10.1261/rna.067843.118⟩
International audience; Contribution of basal cellular processes to the regulation of tissue homeostasis has just started to be appreciated. However, our knowledge on the modulation of ribosome biogenesis activity in situ within specific lineages rem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715cfc45e79cff52c132376e0ab9ea14
https://hal-pasteur.archives-ouvertes.fr/pasteur-01921130/document
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6
Notchless defines a stage-specific requirement for ribosome biogenesis during lineage progression in adult skeletal myogenesis
Autor: Barbara Gayraud-Morel, Marie Le Bouteiller, Michel Cohen-Tannoudji, Shahragim Tajbakhsh, Pierre-Henri Commere
Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2018, 145 (23), pp.dev162636. ⟨10.1242/dev.162636⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (23), pp.dev162636. ⟨10.1242/dev.162636⟩
Cell fate decisions occur through the action of multiple factors, including signalling molecules and transcription factors. Recently, the regulation of translation has emerged as an important step for modulating cellular function and fate, as exempli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2678062899ca5ab0415f26c2699c6a15
https://pubmed.ncbi.nlm.nih.gov/30478226
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7
Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells
Autor: Michel Cohen-Tannoudji, Sandrine Vandormael-Pournin, Marie Le Bouteiller, Florence Bernex, Ana Cumano, Aline Stedman, Odile Burlen-Defranoux, Sarah Beck-Cormier, Celine Souilhol
Publikováno v: Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2013, 210 (11), pp.2351-69. ⟨10.1084/jem.20122019⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, 2013, 210 (11), pp.2351-69. ⟨10.1084/jem.20122019⟩
Conditional deletion of Notchless leads to rapid deletion and exhaustion of HSCs and early progenitor cells, whereas committed progenitor cells survive as a result of differences in ribosomal biogenesis.
Blood cell production relies on the coord
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3abb691a56c50cd4976580fcb78f6a
https://hal-pasteur.archives-ouvertes.fr/pasteur-00881090
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