Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marie Knockaert"'
Autor:
Ziad Al Tanoury, Shahragim Tajbakhsh, Barbara Gayraud-Morel, Philippe Moncuquet, Jérome Chal, Jean-Marie Garnier, Olivier Pourquié, Olivier Tassy, Agata Bera, Olga Sumara, Masayuki Oginuma, Alexis Hubaud, Getzabel Guevara, Leif Kennedy, Marie Knockaert, Ayako Miyanari, Bénédicte Gobert
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩
Development (Cambridge, England), 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩
The work described in this article is partially covered by patent application PCT/EP2012/066793 (publication number WO2013030243 A1). O.P., J.C. and M.K. are co-founders and shareholders of Anagenesis Biotechnologies, a start-up company specializing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c879a49492fae97230915caf68540b0
https://hal-pasteur.archives-ouvertes.fr/pasteur-03217358
https://hal-pasteur.archives-ouvertes.fr/pasteur-03217358
Autor:
Marie Knockaert, Olga Sumara, Olivier Tassy, Philippe Moncuquet, Leif Kennedy, Jérome Chal, Ziad Al Tanoury, Jean-Marie Garnier, Ayako Miyanari, Bénédicte Gobert, Agata Bera, Shahragim Tajbakhsh, Masayuki Oginuma, Barbara Gayraud-Morel, Olivier Pourquié, Getzabel Guevara
In vertebrates, body skeletal muscles and axial skeleton derive from the paraxial mesoderm which flanks the neural tube and notochord. The paraxial mesoderm forms in the posterior region of the embryo as presomitic mesoderm (PSM), which generates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b76445863bb8698c02bce32548a6ab4
https://doi.org/10.1101/140574
https://doi.org/10.1101/140574
Autor:
Laurent Meijer, Marie Knockaert, Anja Becker, Yoan Ferandin, Lutz Preu, Conrad Kunick, Simone Kohfeld, Karen Wieking, Annette Lader, Tanja Pies
Publikováno v:
European Journal of Medicinal Chemistry. 45:335-342
A collection of paullones was tested for inhibitory activity against mitochondrial malate dehydrogenase (mMDH) as a biological target for antiproliferative activity. Based on the results of this screening, 5-benzylpaullones and paullone-9-carboxylic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a921d272b3946e5031b3e38dd7b4a9fe
https://doi.org/10.1016/j.ejmech.2009.10.018
https://doi.org/10.1016/j.ejmech.2009.10.018
Autor:
Joan Massagué, Gopal P. Sapkota, Ermelinda Montalvo, Ali H. Brivanlou, Claudio Alarcón, Marie Knockaert
Publikováno v:
Journal of Biological Chemistry. 281:40412-40419
Smad proteins transduce bone morphogenetic protein (BMP) and transforming growth factor-beta (TGFbeta) signals upon phosphorylation of their C-terminal SXS motif by receptor kinases. The activity of Smad1 in the BMP pathway and Smad2/3 in the TGFbeta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225add27c2c4e4fdc09393669896dcdd
https://doi.org/10.1074/jbc.m610172200
https://doi.org/10.1074/jbc.m610172200
Publikováno v:
Proceedings of the National Academy of Sciences. 103:11940-11945
Smad transcription factors are key signal transducers for the TGF-β/bone morphogenetic protein (BMP) family of cytokines and morphogens. C-terminal serine phosphorylation by TGF-β and BMP membrane receptors drives Smads into the nucleus as transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9876f46c34b0ac8f21fb392f15691b3
https://doi.org/10.1073/pnas.0605133103
https://doi.org/10.1073/pnas.0605133103
Autor:
Jacint Boix, Karima Bettayeb, Frank Totzke, Alexios-Leandros Skaltsounis, Jan Mester, Xènia Garrofé-Ochoa, Laurent Meijer, Panos Polychronopoulos, Yoan Ferandin, Prokopios Magiatis, Judit Ribas, Marie Knockaert, Christoph Schächtele
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Oncogene
Oncogene, Nature Publishing Group, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncogene, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩
Universitad de Lleida
Oncogene
Oncogene, Nature Publishing Group, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncogene, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩
Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3) as well as an agonist of the aryl hydrocarbon receptor (AhR). Indirubin is the active ingredient of a traditional Chines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5905aba6a45aa9ccd7ee5d0dd9704b32
https://doi.org/10.1038/sj.onc.1209648
https://doi.org/10.1038/sj.onc.1209648
Autor:
Olivier Lozach, Laurent Meijer, Sophie Schmitt, Flavio Meggio, Christoph Schächtele, Yongqin Wan, Amancio Carnero, Lin Tang, Frank Totzke, Stéphane Bach, Nathanael S. Gray, Stephen P. Coburn, Jens Reinhardt, Marcel Koken, Jean-Francois Dierick, Tao Jiang, Marie Knockaert, Lorenzo A. Pinna, Hervé Galons, Dong-Cai Liang, Blandine Baratte, Andrea S. Lerman
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2005, 280, pp.31208-31219. ⟨10.1074/jbc.m500806200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280, pp.31208-31219
Journal of Biological Chemistry, 2005, 280, pp.31208-31219
Journal of Biological Chemistry, 2005, 280, pp.31208-31219. ⟨10.1074/jbc.m500806200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280, pp.31208-31219
Journal of Biological Chemistry, 2005, 280, pp.31208-31219
International audience; Roscovitine (CYC202) is often referred to as a "selective inhibitor of cyclin-dependent kinases." Besides its use as a biological tool in cell cycle, neuronal functions, and apoptosis studies, it is currently evaluated as a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6754a9bfd581c2409740f024a262fd39
https://doi.org/10.1074/jbc.m500806200
https://doi.org/10.1074/jbc.m500806200
Autor:
Gustave Moonen, Marie Knockaert, Laurent Meijer, Shibeshih Belachew, Laurent Nguyen, Brigitte Malgrange, Philippe Lefèbvre
Publikováno v:
The FASEB Journal. 17:1-26
In the embryonic day 19 organs of Corti, we showed that roscovitine, a chemical inhibitor of cyclin-dependent kinases (CDKs), significantly increased the number of hair cells (HCs) and corresponding supporting cells (SCs) by triggering differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ac896d0bb91304622fb2850917488d
https://doi.org/10.1096/fj.03-0035fje
https://doi.org/10.1096/fj.03-0035fje
Autor:
Jacques Pouysségur, Philippe Lenormand, Peter G. Schultz, Laurent Meijer, Marie Knockaert, Nathanael S. Gray
Publikováno v:
Oncogene. 21:6413-6424
Chemical inhibitors of cyclin-dependent kinases (CDKs) have a great therapeutic potential against various proliferative and neurodegenerative disorders. Intensive screening of a combinatorial chemistry library of 2,6,9-trisubstituted purines has led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7827a1b27bdd1ed402df884d7a1de3a
https://doi.org/10.1038/sj.onc.1205908
https://doi.org/10.1038/sj.onc.1205908
Publikováno v:
Trends in Pharmacological Sciences. 23:417-425
Cyclin-dependent kinases (CDKs) regulate the cell division cycle, apoptosis, transcription and differentiation in addition to functions in the nervous system. Deregulation of CDKs in various diseases has stimulated an intensive search for selective p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccfbbe3183d56a3f8a6ad3208238eba
https://doi.org/10.1016/s0165-6147(02)02071-0
https://doi.org/10.1016/s0165-6147(02)02071-0