Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marie José T. H. Goumans"'
Autor:
Yang Ge, Lieke van Roon, Janine M. van Gils, Tom Geestman, Conny J. van Munsteren, Anke M. Smits, Marie José T. H. Goumans, Marco C. DeRuiter, Monique R. M. Jongbloed
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
A role for cardiac sympathetic hyperinnervation in arrhythmogenesis after myocardial infarction (MI) has increasingly been recognized. In humans and mice, the heart receives cervical as well as thoracic sympathetic contributions. In mice, superior ce
Externí odkaz:
https://doaj.org/article/c241aff704f640e7945fc064aa5866f0
Autor:
Alwin de Jong, Vincent Q. Sier, Hendrika A. B. Peters, Natalia K. M. Schilder, J. Wouter Jukema, Marie José T. H. Goumans, Paul H. A. Quax, Margreet R. de Vries
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
AimsVein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β via TGFβR2 or BMP9/10 via BMPR2, which is an important pathway in fibr
Externí odkaz:
https://doaj.org/article/e151280a58d144afbb3c54ab231778f6
Autor:
Antoinette F. van Ouwerkerk, Fernanda M. Bosada, Karel van Duijvenboden, Matthew C. Hill, Lindsey E. Montefiori, Koen T. Scholman, Jia Liu, Antoine A. F. de Vries, Bastiaan J. Boukens, Patrick T. Ellinor, Marie José T. H. Goumans, Igor R. Efimov, Marcelo A. Nobrega, Phil Barnett, James F. Martin, Vincent M. Christoffels
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The majority of disease-associated genetic variants lie in non-coding regions. Here the authors generated and compiled human transcriptomic, epigenomic and chromatin conformation datasets, to identify genes associated with atrial fibrillation and fun
Externí odkaz:
https://doaj.org/article/6c47420fc1c646169658c86522780b7c
Autor:
Anna M. D. Végh, Arie O. Verkerk, Lucía Cócera Ortega, Jianan Wang, Dirk Geerts, Mischa Klerk, Kirsten Lodder, Ruby Nobel, Anke J. Tijsen, Harsha D. Devalla, Vincent M. Christoffels, Max Medina-Ramírez, Anke M. Smits, Hanno L. Tan, Ronald Wilders, Marie José T. H. Goumans, Gerard J. J. Boink
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Electronic pacemakers still face major shortcomings that are largely intrinsic to their hardware-based design. Radical improvements can potentially be generated by gene or cell therapy-based biological pacemakers. Our previous work identified adenovi
Externí odkaz:
https://doaj.org/article/177579aa19c249d1bc638e48791bd6e1
Autor:
Yang Ge, Anke M. Smits, Jia Liu, Juan Zhang, Thomas J. van Brakel, Marie José T. H. Goumans, Monique R. M. Jongbloed, Antoine A. F. de Vries
Publikováno v:
Cells, Vol 10, Iss 8, p 2064 (2021)
Rationale: In recent decades, the great potential of human epicardium-derived cells (EPDCs) as an endogenous cell source for cardiac regeneration has been recognized. The limited availability and low proliferation capacity of primary human EPDCs and
Externí odkaz:
https://doaj.org/article/43503c722cb647e0a3468a8bd367c631
Autor:
Joshua C. Peterson, Tim P. Kelder, Marie José T. H. Goumans, Monique R. M. Jongbloed, Marco C. DeRuiter
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 5, p 47 (2021)
Whilst knowledge regarding the pathophysiology of congenital heart disease (CHDs) has advanced greatly in recent years, the underlying developmental processes affecting the cardiac outflow tract (OFT) such as bicuspid aortic valve, tetralogy of Fallo
Externí odkaz:
https://doaj.org/article/9b39efbce8554f41b7be1b1e590c566e
Autor:
Vincent Q. Sier, Joost R. van der Vorst, Paul H. A. Quax, Margreet R. de Vries, Elham Zonoobi, Alexander L. Vahrmeijer, Ilona A. Dekkers, Lioe-Fee de Geus-Oei, Anke M. Smits, Weibo Cai, Cornelis F. M. Sier, Marie José T. H. Goumans, Lukas J. A. C. Hawinkels
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4804 (2021)
Molecular imaging of pathologic lesions can improve efficient detection of cancer and cardiovascular diseases. A shared pathophysiological feature is angiogenesis, the formation of new blood vessels. Endoglin (CD105) is a coreceptor for ligands of th
Externí odkaz:
https://doaj.org/article/0f5d828bcae344d0835104412a61b484
Autor:
Wineke Bakker, Calinda K. E. Dingenouts, Kirsten Lodder, Karien C. Wiesmeijer, Alwin de Jong, Kondababu Kurakula, Hans-Jurgen J. Mager, Anke M. Smits, Margreet R. de Vries, Paul H. A. Quax, Marie José T. H. Goumans
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2010 (2021)
Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor endoglin. Endoglin haploinsufficiency results in vascular malformations and impaired neoangiogenesis. Furthermore, HHT1
Externí odkaz:
https://doaj.org/article/90b85094c14344aa8023dd031682d605
Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing
Autor:
Anna M. D. Végh, A. Dénise den Haan, Lucía Cócera Ortega, Arie O. Verkerk, Joost P. G. Sluijter, Diane Bakker, Shirley van Amersfoorth, Toon A. B. van Veen, Mischa Klerk, Jurgen Seppen, Jacques M. T. de Bakker, Vincent M. Christoffels, Dirk Geerts, Marie José T. H. Goumans, Hanno L. Tan, Gerard J. J. Boink
Publikováno v:
Molecules, Vol 24, Iss 1, p 181 (2019)
Sustained pacemaker function is a challenge in biological pacemaker engineering. Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation. We studied whether lentivirally transduced CMPCs that e
Externí odkaz:
https://doaj.org/article/12417958c72040618ab4b2122a3ff7c4
Autor:
Niels Harlaar, Sven O. Dekker, Juan Zhang, Rebecca R. Snabel, Marieke W. Veldkamp, Arie O. Verkerk, Carla Cofiño Fabres, Verena Schwach, Lente J. S. Lerink, Mathilde R. Rivaud, Aat A. Mulder, Willem E. Corver, Marie José T. H. Goumans, Dobromir Dobrev, Robert J. M. Klautz, Martin J. Schalij, Gert Jan C. Veenstra, Robert Passier, Thomas J. van Brakel, Daniël A. Pijnappels, Antoine A. F. de Vries
Publikováno v:
Nature Biomedical Engineering, 6, 389-402
Nature Biomedical Engineering, 6, 389-402. Nature Publishing Group
Nature Biomedical Engineering, 6, 4, pp. 389-402
Nature Biomedical Engineering. NATURE PORTFOLIO
Nature Biomedical Engineering
Nature Biomedical Engineering, 6(4), 389-402. Nature Publishing Group
Nature Biomedical Engineering, 6, 389-402. Nature Publishing Group
Nature Biomedical Engineering, 6, 4, pp. 389-402
Nature Biomedical Engineering. NATURE PORTFOLIO
Nature Biomedical Engineering
Nature Biomedical Engineering, 6(4), 389-402. Nature Publishing Group
Functional human atrial myocytes derived from foetal atrial tissue can be massively expanded via a conditional cell-immortalization method, and used in in vitro models of atrial fibrillation.The lack of a scalable and robust source of well-differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d70ba6fcbebb587ffe9e4ecc6d3c032
http://hdl.handle.net/2066/251610
http://hdl.handle.net/2066/251610