Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Marie J. Desierto"'
Autor:
Xingmin Feng, Zenghua Lin, Wanling Sun, Maile K. Hollinger, Marie J. Desierto, Keyvan Keyvanfar, Daniela Malide, Pawel Muranski, Jichun Chen, Neal S. Young
Publikováno v:
Haematologica, Vol 102, Iss 10 (2017)
Acquired aplastic anemia, the prototypical bone marrow failure disease, is characterized by pancytopenia and marrow hypoplasia. Most aplastic anemia patients respond to immunosuppressive therapy, usually with anti-thymocyte globulin and cyclosporine,
Externí odkaz:
https://doaj.org/article/7917e96a806e40648342fd8c0c5a6d84
Autor:
Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young
Publikováno v:
Haematologica, Vol 102, Iss 1 (2017)
Aplastic anemia is an acquired bone marrow failure characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the bone marrow. In aplastic anemia, a majo
Externí odkaz:
https://doaj.org/article/793e53c3a82b46609f93744072bbc31c
Autor:
Kazuya Sato, Xingmin Feng, Jichun Chen, Jungang Li, Pawel Muranski, Marie J. Desierto, Keyvan Keyvanfar, Daniela Malide, Sachiko Kajigaya, Neal S. Young
Publikováno v:
Haematologica, Vol 101, Iss 1 (2016)
Acquired aplastic anemia is an immune-mediated disease, in which T cells target hematopoietic cells; at presentation, the bone marrow is replaced by fat. It was reported that bone marrow adipocytes were negative regulators of hematopoietic microenvir
Externí odkaz:
https://doaj.org/article/11ae4f78ce3642a9870ccb0875c9f8d9
Autor:
Valeria Visconte, Nalini Raghavachari, Delong Liu, Keyvan Keyvanfar, Marie J. Desierto, Jichun Chen, Neal S. Young
Publikováno v:
Haematologica, Vol 95, Iss 2 (2010)
Background Somatic mutation in the X-linked phosphatidylinositol glycan class A gene (PIG-A) causes glycosyl phosphatidylinositol anchor deficiency in human patients with paroxysmal nocturnal hemoglobinuria.Design and Methods We produced an animal mo
Externí odkaz:
https://doaj.org/article/4bb77a47a0ba4c2bbde739dd43b62f2d
Autor:
Wanling Sun, Pawel Muranski, Jichun Chen, Zenghua Lin, Marie J. Desierto, Xingmin Feng, Keyvan Keyvanfar, Maile K. Hollinger, Neal S. Young, Daniela Malide
Publikováno v:
Haematologica
Acquired aplastic anemia, the prototypical bone marrow failure disease, is characterized by pancytopenia and marrow hypoplasia. Most aplastic anemia patients respond to immunosuppressive therapy, usually with anti-thymocyte globulin and cyclosporine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46ff886d3e95b2b1c3469b93298f3e4
https://doi.org/10.3324/haematol.2017.163675
https://doi.org/10.3324/haematol.2017.163675
Autor:
Phillip Scheinberg, Kohei Hosokawa, Barbara Weinstein, Maria del Pilar Fernandez Ibanez, Marie J. Desierto, Olga Rios, Neal S. Young, Sachiko Kajigaya, Danielle M. Townsley, Xingmin Feng
Publikováno v:
Haematologica. 102:69-78
Background. Aplastic anemia (AA) is an acquired bone marrow (BM) disease characterized by marrow hypoplasia, a paucity of hematopoietic stem and progenitor cells, and pancytopenia of the peripheral blood, due to immune attack on the BM. Although the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a770fb9fbd099850a31538afd1d1b3
https://doi.org/10.3324/haematol.2016.151076
https://doi.org/10.3324/haematol.2016.151076
Publikováno v:
Blood. 126:2621-2631
Interferon gamma (IFN-γ) has been reported to have both negative and positive activity on hematopoietic cells, adding complexity to the interpretation of its pleiotropic functions. We examined the effects of IFN-γ on murine hematopoietic stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076f4b4bf752e921dcc7d364f5d49650
https://doi.org/10.1182/blood-2015-06-652453
https://doi.org/10.1182/blood-2015-06-652453
Autor:
Andre Larochelle, Marie J. Desierto, Colin Wu, Thomas Winkler, Katherine R. Calvo, James K. Cooper, Danielle M. Townsley, David J. Young, Ronan Desmond, Sophia Grasmeder, Janet Valdez, Ruba Shalhoub, Neal S. Young, Cynthia E. Dunbar, Jennifer Lotter, Xing Fan, Phillip Scheinberg
Publikováno v:
Blood. 133(24)
Eltrombopag (EPAG) received approval from the US Food and Drug Administration for the treatment of refractory severe aplastic anemia (rSAA) based on treatment of 43 patients with doses escalating from 50 to 150 mg daily for 12 weeks. Response kinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d31e29e056e27602078f69e9f22fad
https://pubmed.ncbi.nlm.nih.gov/31196876
https://pubmed.ncbi.nlm.nih.gov/31196876
Autor:
Susan Wong, Xingmin Feng, Adeline Bertola, Sachiko Kajigaya, Danielle M. Townsley, Marie J. Desierto, Jichun Chen, Neal S. Young, Flavia S. Donaires, Raquel M. Alves-Paiva, Rodrigo T. Calado, Bin Gao
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background & Aims Short telomeres and genetic telomerase defects are risk factors for some human liver diseases, ranging from non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) to cirrhosis. In murine models, telomere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd2a01c0728709bf64a5ecf6a15aa17
Autor:
Robert C. Lacy, Glen Alaks, Xin Zhao, Jichun Chen, Bogdan Dumitriu, Sachiko Kajigaya, Danielle M. Townsley, Neal S. Young, Marie J. Desierto, Yasutaka Ueda
Publikováno v:
Gene. 568:8-18
Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase complex that regulates telomerase activity to maintain telomere length for all animals with linear chromosomes. As the Mus musculus (MM) laboratory mouse has very long tel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83da8f76f14c83c664dea51b3c02472
https://doi.org/10.1016/j.gene.2015.05.013
https://doi.org/10.1016/j.gene.2015.05.013