Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marie Ito"'
Autor:
Marie Ito, Gloria Michelle Ducasa, Judith David Molina, Javier Varona Santos, Shamroop Kumar Mallela, Jin Ju Kim, Mengyuan Ge, Alla Mitrofanova, Alexis Sloan, Sandra Merscher, Imari Mimura, Alessia Fornoni
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Decreased ATP Binding Cassette Transporter A1 (ABCA1) expression and caspase-4-mediated noncanonical inflammasome contribution have been described in podocytes in diabetic kidney disease (DKD). To investigate a link between these pathways, w
Externí odkaz:
https://doaj.org/article/9ff64306c5904d43921755a62b6da09d
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 351 (2022)
Mitochondrial dysfunction plays an important role in the pathogenesis and progression of diabetic kidney disease (DKD). In this review, we will discuss mitochondrial dysfunction observed in preclinical models of DKD as well as in clinical DKD with a
Externí odkaz:
https://doaj.org/article/e8afcbb829cb43bbae67a230e356f22d
Autor:
Akihito Yamamoto, Seiryu Kamoi, Keisuke Kurose, Marie Ito, Toshiyuki Takeshita, Shoko Kure, Katsuichi Sakamoto, Yuji Sato, Masao Miyashita
Publikováno v:
Cancers, Vol 12, Iss 11, p 3291 (2020)
(1) Background: Previous reports have indicated that cancers of the stomach, lung, and pancreas can be detected by dog sniffing, but results have been varied. Here, a highly trained dog was used to determine whether urine from patients with cervical
Externí odkaz:
https://doaj.org/article/4f45834b05374faabd655425027f042a
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105963 (2014)
On the basis of observational and experimental evidence, several authors have proposed that contagious yawn is linked to our capacity for empathy, thus presenting a powerful tool to explore the root of empathy in animal evolution. The evidence for th
Externí odkaz:
https://doaj.org/article/01d3f4ba5479415da4f549a843103028
Autor:
Alla Mitrofanova, Antonio Fontanella, Matthew Tolerico, Shamroop Mallela, Judith Molina David, Yiqin Zuo, Marcia Boulina, Jin-Ju Kim, Javier Santos, Mengyuan Ge, Alexis Sloan, Wadih Issa, Margaret Gurumani, Jeffrey Pressly, Marie Ito, Matthias Kretzler, Sean Eddy, Robert Nelson, Sandra Merscher, George Burke, Alessia Fornoni
Publikováno v:
Journal of the American Society of Nephrology. 33:2153-2173
The signaling molecule stimulator of IFN genes (STING) was identified as a crucial regulator of the DNA-sensing cyclic GMP-AMP synthase (cGAS)-STING pathway, and this signaling pathway regulates inflammation and energy homeostasis under conditions of
Publikováno v:
Kidney International. 97:687-701
Hypoxia-inducible factor (HIF) mediates protection via hypoxic preconditioning in both, in vitro and in vivo ischemia models. However, the underlying mechanism remains largely unknown. Prolyl hydroxylase domain proteins serve as the main HIF regulato
Autor:
Marie Ito, Masaomi Nangaku
Publikováno v:
Kidney International. 96:823-825
Bardoxolone methyl activates nuclear factor erythroid 2-related factor 2 and increases glomerular filtration rate in patients with diabetic kidney disease. Because bardoxolone methyl also increases albuminuria, Rossing and colleagues performed a retr
Autor:
Marie Ito, Tetsuhiro Tanaka
Publikováno v:
Internal Medicine
Sodium-glucose cotransporter 2 (SGLT2), which is specifically expressed on the apical side of proximal tubular cells, is involved in the reabsorption of most of the glucose filtered by the glomeruli, and its inhibitors are gaining publicity as potent
Publikováno v:
Current opinion in nephrology and hypertension. 29(1)
Purpose of review Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates a wider range of downstream pathways than previously thought. This review focuses on the novel findings about the internal regulatory mecha
Autor:
Masaomi Nangaku, Sho Hasegawa, Yoshiki Higashijima, Mai Sugahara, Hisako Saito, Lisa Uchida, Takeshi Wakashima, Tetsuhiro Tanaka, Marie Ito, Shinji Tanaka, Kenji Fukui, Junna Yamaguchi
Publikováno v:
Physiological Reports
Recent epidemiologic studies revealed a correlation between acute kidney injury (AKI) episodes and the progression to chronic kidney disease (CKD). Although the severity and duration of the initial insult likely predict the development of CKD, inform