Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marie Goutierre"'
Autor:
Marie Goutierre, Sana Al Awabdh, Florian Donneger, Emeline François, Daniel Gomez-Dominguez, Theano Irinopoulou, Liset Menendez de la Prida, Jean Christophe Poncer
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 91-103.e7 (2019)
Summary: KCC2 regulates neuronal transmembrane chloride gradients and thereby controls GABA signaling in the brain. KCC2 downregulation is observed in numerous neurological and psychiatric disorders. Paradoxical, excitatory GABA signaling is usually
Externí odkaz:
https://doaj.org/article/e639bdd041d9453db79f8a9062f7a422
Autor:
Sabine Lévi, Marion Russeau, Oana Vigy, Martial Séveno, Philippe Marin, Florian Donneger, Pauline Weinzettl, Sana Al Awabdh, Marie Goutierre, Imane Moutkine, Jean Christophe Poncer
Publikováno v:
J Neurosci
The K+-Cl–cotransporter KCC2, encoded by theSlc12a5gene, is a neuron-specific chloride extruder that tunes the strength and polarity of GABAAreceptor-mediated transmission. In addition to its canonical ion transport function, KCC2 also regulates sp
Autor:
Clémence Simonnet, Manisha Sinha, Marie Goutierre, Imane Moutkine, Stéphanie Daumas, Jean Christophe Poncer
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, 2022, Online ahead of print. ⟨10.1038/s41386-022-01480-5⟩
Neuropsychopharmacology, 2022, Online ahead of print. ⟨10.1038/s41386-022-01480-5⟩
Delayed upregulation of the neuronal chloride extruder KCC2 underlies the progressive shift in GABA signaling polarity during development. Conversely, KCC2 downregulation is observed in a variety of neurological and psychiatric disorders often associ
Autor:
Liset Menendez de la Prida, Emeline François, Sana Al Awabdh, Jean Christophe Poncer, Daniel Gomez-Dominguez, Theano Irinopoulou, Marie Goutierre
The K+/Cl− co-transporter KCC2 (SLC12A5) regulates neuronal transmembrane chloride gradients and thereby controls GABA signaling in the brain. KCC2 downregulation is observed in several neurological and psychiatric disorders including epilepsy, neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a185e7c01b0ce060a4172fe659329a
https://doi.org/10.1101/434571
https://doi.org/10.1101/434571
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2016, 19 (7), pp.959-964. ⟨10.1038/nn.4304⟩
Nature Neuroscience, Nature Publishing Group, 2016, 19 (7), pp.959-964. ⟨10.1038/nn.4304⟩
Memory consolidation is thought to involve a hippocampo-cortical dialog during sleep to stabilize labile memory traces for long-term storage. However, direct evidence supporting this hypothesis is lacking. We dynamically manipulated the temporal coor
Autor:
Jennifer Bernard, Carsten Janke, Theano Irinopoulou, Jean Christophe Poncer, Preety Shabajee, Xavier H. Jaglin, Mythili Savariradjane, Richard Belvindrah, Kathiresan Natarajan, Marie Goutierre, Elodie Bruel-Jungerman, Imane Moutkine, Fiona Francis
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (8), pp.2443-2461. ⟨10.1083/jcb.201607074⟩
Journal of Cell Biology, 2017, 216 (8), pp.2443-2461. ⟨10.1083/jcb.201607074⟩
The Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (8), pp.2443-2461. ⟨10.1083/jcb.201607074⟩
Journal of Cell Biology, 2017, 216 (8), pp.2443-2461. ⟨10.1083/jcb.201607074⟩
The Journal of Cell Biology
Mutation of α-tubulin isotypes is associated with cortical malformations. Belvindrah et al. show that Tuba1 mutation leads to impaired neuronal saltatory migration in vivo as a result of functional and structural microtubule defects. Comparative ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b5eefaf78e0cbcf0433bce29c32f7b
https://hal.sorbonne-universite.fr/hal-01921230
https://hal.sorbonne-universite.fr/hal-01921230
Autor:
Quentin Chevy, Jean Christophe Poncer, Martin Heubl, Emmanuel Eugène, Marie Goutierre, Stéphanie Backer, Evelyne Bloch-Gallego, Imane Moutkine, Sabine Lévi
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (48), pp.15772-15786. ⟨10.1523/JNEUROSCI.1735-15.2015⟩
Journal of Neuroscience, Society for Neuroscience, 2015, 35 (48), pp.15772-15786. ⟨10.1523/JNEUROSCI.1735-15.2015⟩
Expression of the neuronal K/Cl transporter KCC2 is tightly regulated throughout development and by both normal and pathological neuronal activity. Changes in KCC2 expression have often been associated with altered chloride homeostasis and GABA signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfc415895e9bd3ecc3ee6d223511a43
https://europepmc.org/articles/PMC6605455/
https://europepmc.org/articles/PMC6605455/