Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marie Gottar"'
Publikováno v:
Drugs in R&D, Vol 19, Iss 2, Pp 127-140 (2019)
Abstract Objective PF-06438179/GP1111 (PF-SZ-IFX) is an infliximab biosimilar. We evaluated the extended in-use physicochemical and biological stability of PF-SZ-IFX upon preparation for intravenous infusion. Methods Two batches of PF-SZ-IFX were rec
Externí odkaz:
https://doaj.org/article/8a76a108db784f8aa23f4e1e818c5e63
Publikováno v:
International Reviews of Immunology. 31:166-173
Bone marrow kinase on chromosome X (BMX) is a cytosolic tyrosine kinase and a member of the TEC kinase family. BMX is expressed in hematopoietic cells of the myeloid lineage where it participates in the immune response. It is also involved in the res
Autor:
Jacques Baudier, Elodie Engel, Amélie Avet-Rochex, Marie Gottar, Marie-Odile Fauvarque, Emmanuel Taillebourg, Hervé Tricoire, Evelyne Bergeret, Christelle Benaud, Dominique Thevenon
Publikováno v:
Cell Host & Microbe. 6(4):309-320
Summary Ubiquitin proteases remove ubiquitin monomers or polymers to modify the stability or activity of proteins and thereby serve as key regulators of signal transduction. Here, we describe the function of the Drosophila ubiquitin-specific protease
Publikováno v:
Journal of Biological Chemistry. 283:21487-21494
The intracellular signaling pathway by which tumor necrosis factor (TNF) induces its pleiotropic actions is well characterized and includes unique components as well as modules shared with other signaling pathways. In addition to the currently known
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2007, 23 (8-9), pp.707-709. ⟨10.1051/medsci/20072389707⟩
médecine/sciences, EDP Sciences, 2007, 23 (8-9), pp.707-709. ⟨10.1051/medsci/20072389707⟩
> La detection des infections est une etape primordiale de la reponse immunitaire. Longtemps consideres comme l’apanage de la reponse adaptative, les phenomenes de reconnaissance du « non-soi potentiellement pathogene » sont apparus, a la lumiere
Autor:
Amanda Littlewood-Evans, Craig Mickanin, Kari Alitalo, Bruno Cenni, Matthias Mueller, Francis Dodeller, Mark Labow, Samuel Gaveriaux, Bernd Kinzel, Marie Gottar-Guillier, Dieter Huesken, Vadim Iourgenko
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(10)
Inflammatory cytokines like TNF play a central role in autoimmune disorders such as rheumatoid arthritis. We identified the tyrosine kinase bone marrow kinase on chromosome X (BMX) as an essential component of a shared inflammatory signaling pathway.
Publikováno v:
Medecine sciences : M/S. 23(8-9)
Autor:
Tariq M. Butt, Vanessa Gobert, Jules A. Hoffmann, Alexey A. Matskevich, Marie Gottar, Marcia Belvin, Chengshu Wang, Jean-Marc Reichhart, Dominique Ferrandon
Publikováno v:
Cell
Cell, Elsevier, 2006, 127 (7), pp.1425-1437. ⟨10.1016/j.cell.2006.10.046⟩
Cell, Elsevier, 2006, 127 (7), pp.1425-1437. ⟨10.1016/j.cell.2006.10.046⟩
International audience; The Drosophila immune system discriminates between various types of infections and activates appropriate signal transduction pathways to combat the invading microorganisms. The Toll pathway is required for the host response ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa9656c0864d5a95fb9a1af8ecfad92
https://cronfa.swan.ac.uk/Record/cronfa1491
https://cronfa.swan.ac.uk/Record/cronfa1491
Autor:
Julien Royet, Dominique Ferrandon, Marcia Belvin, Alexey A. Matskevich, Sophie Rutschmann, Marie Gottar, Vanessa Gobert, Jules A. Hoffmann
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2003, 302 (5653), pp.2126-2130. ⟨10.1126/science.1085432⟩
Science, American Association for the Advancement of Science, 2003, 302, pp.2126-2130
HAL
Science, 2003, 302 (5653), pp.2126-2130. ⟨10.1126/science.1085432⟩
Science, 2003, 302, pp.2126-2130
Science, American Association for the Advancement of Science, 2003, 302 (5653), pp.2126-2130. ⟨10.1126/science.1085432⟩
Science, American Association for the Advancement of Science, 2003, 302, pp.2126-2130
HAL
Science, 2003, 302 (5653), pp.2126-2130. ⟨10.1126/science.1085432⟩
Science, 2003, 302, pp.2126-2130
The Toll- dependent defense against Gram-positive bacterial infections in Drosophila is mediated through the peptidoglycan recognition protein SA (PGRP-SA). A mutation termed osiris disrupts the Gram-negative binding protein 1 ( GNBP1 ) gene and lead
Publikováno v:
Blood. 99(8)
Self-renewal, pluripotency, and long-term reconstitution are defining characteristics of single hematopoietic stem cells.Pax5−/− precursor B cells apparently possess similar characteristics. Here, using serial transplantations, with in vitro recl