Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie Frickenhaus"'
Autor:
Marica Catinozzi, Moushami Mallik, Marie Frickenhaus, Marije Been, Céline Sijlmans, Divita Kulshrestha, Ioannis Alexopoulos, Manuela Weitkunat, Frank Schnorrer, Erik Storkebaum
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008731 (2020)
The number of adult myofibers in Drosophila is determined by the number of founder myoblasts selected from a myoblast pool, a process governed by fibroblast growth factor (FGF) signaling. Here, we show that loss of cabeza (caz) function results in a
Externí odkaz:
https://doaj.org/article/5bd4730f59684d6ba9b691d42c77b6e4
Autor:
Marcel Naumann, Arun Pal, Anand Goswami, Xenia Lojewski, Julia Japtok, Anne Vehlow, Maximilian Naujock, René Günther, Mengmeng Jin, Nancy Stanslowsky, Peter Reinhardt, Jared Sterneckert, Marie Frickenhaus, Francisco Pan-Montojo, Erik Storkebaum, Ina Poser, Axel Freischmidt, Jochen H. Weishaupt, Karlheinz Holzmann, Dirk Troost, Albert C. Ludolph, Tobias M. Boeckers, Stefan Liebau, Susanne Petri, Nils Cordes, Anthony A. Hyman, Florian Wegner, Stephan W. Grill, Joachim Weis, Alexander Storch, Andreas Hermann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Abnormal cytoplasmic aggregates of FUS are a hallmark of some forms of amyotrophic lateral sclerosis (ALS). Here, using neurons derived from patients with FUS-ALS, the authors demonstrate that impairment of PARP-dependent DNA damage signaling is an e
Externí odkaz:
https://doaj.org/article/421d7fe19126448d9734fe819843c747
Autor:
Simone Prömel, Marie Frickenhaus, Samantha Hughes, Lamia Mestek, David Staunton, Alison Woollard, Ioannis Vakonakis, Torsten Schöneberg, Ralf Schnabel, Andreas P. Russ, Tobias Langenhan
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 321-331 (2012)
Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunity, tumor
Externí odkaz:
https://doaj.org/article/d46d010d9fbc404a8102cca8d868f516
Autor:
Manuela Weitkunat, Marije Been, Erik Storkebaum, Marica Catinozzi, Divita Kulshrestha, Frank Schnorrer, Moushami Mallik, Marie Frickenhaus, Céline Sijlmans, Ioannis Alexopoulos
Publikováno v:
PLoS Genetics
PLoS Genetics, 2020, 16 (4), pp.e1008731. ⟨10.1371/journal.pgen.1008731⟩
Plos Genetics, 16, 1-22
PLoS Genetics, Public Library of Science, 2020, 16 (4), pp.e1008731. ⟨10.1371/journal.pgen.1008731⟩
PLoS Genetics, Public Library of Science, 2020, 16, ⟨10.1371/journal.pgen.1008731⟩
PLoS Genetics, Vol 16, Iss 4, p e1008731 (2020)
PLOS Genetics
Plos Genetics, 16, 4, pp. 1-22
PLOS GENETICS
PLoS Genetics, 2020, 16 (4), pp.e1008731. ⟨10.1371/journal.pgen.1008731⟩
Plos Genetics, 16, 1-22
PLoS Genetics, Public Library of Science, 2020, 16 (4), pp.e1008731. ⟨10.1371/journal.pgen.1008731⟩
PLoS Genetics, Public Library of Science, 2020, 16, ⟨10.1371/journal.pgen.1008731⟩
PLoS Genetics, Vol 16, Iss 4, p e1008731 (2020)
PLOS Genetics
Plos Genetics, 16, 4, pp. 1-22
PLOS GENETICS
The number of adult myofibers in Drosophila is determined by the number of founder myoblasts selected from a myoblast pool, a process governed by fibroblast growth factor (FGF) signaling. Here, we show that loss of cabeza (caz) function results in a
Autor:
Susanne Petri, Florian Wegner, Axel Freischmidt, Albert C. Ludolph, Peter Reinhardt, Arun Pal, Karlheinz Holzmann, Joachim Weis, Anthony A. Hyman, Anand Goswami, Andreas Hermann, Stephan W. Grill, Xenia Lojewski, Marcel Naumann, Anne Vehlow, Julia Japtok, Alexander Storch, Nils Cordes, Francisco Pan-Montojo, Dirk Troost, Mengmeng Jin, Jared Sterneckert, Ina Poser, René Günther, Tobias M. Boeckers, Jochen H. Weishaupt, Erik Storkebaum, Maximilian Naujock, Nancy Stanslowsky, Stefan Liebau, Marie Frickenhaus
Publikováno v:
Nature Communications 9, 335 (2018). doi:10.1038/s41467-017-02299-1
Nature Communications
Nature Communications 9(1), 335 (2018). doi:10.1038/s41467-017-02299-1
Nature communications, 9(1). Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications 9(2018), 335
Nature Communications, 9, pp. 1-17
Nature Communications, 9, 1-17
Nature Communications
Nature Communications 9(1), 335 (2018). doi:10.1038/s41467-017-02299-1
Nature communications, 9(1). Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications 9(2018), 335
Nature Communications, 9, pp. 1-17
Nature Communications, 9, 1-17
Amyotrophic lateral sclerosis (ALS) is the most frequent motor neuron disease. Cytoplasmic fused in sarcoma (FUS) aggregates are pathological hallmarks of FUS-ALS. Proper shuttling between the nucleus and cytoplasm is essential for physiological cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e83528d7f7c7ee164b556332b6e9382
https://publications.rwth-aachen.de/record/757240
https://publications.rwth-aachen.de/record/757240
Autor:
Maximilian Naujock, Stefan Liebau, Florian Wegner, Marie Frickenhaus, Moritz Klingenstein, Tobias M. Boeckers, Albert C. Ludolph, Ekaterini Kefalakes, Maria Demestre, Marcel Naumann, Alexander Storch, Stefan Putz, Nancy Stanslowsky, Franziska Bursch, Andreas Hermann, Reinhard Dengler, Kwang-Soo Kim, Susanne Petri, Sebastian Bufler, Xenia Lojewski, Jared Sterneckert, Peter Reinhardt, Carola Kassebaum
Publikováno v:
Stem cells 34(6), 1563-1575 (2016). doi:10.1002/stem.2354
Despite decades of research on amyotrophic lateral sclerosis (ALS), there is only one approved drug, which minimally extends patient survival. Here, we investigated pathophysiological mechanisms underlying ALS using motor neurons (MNs) differentiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e6d415d7ea6d1e7ff503f00ac0df44
Autor:
Lamia Mestek, Simone Prömel, Ralf Schnabel, Marie Frickenhaus, Torsten Schöneberg, Samantha Jane Hughes, David Staunton, Andreas Russ, Tobias Langenhan, Alison Woollard, Ioannis Vakonakis
Publikováno v:
Cell Reports
Cell Reports, Vol 2, Iss 3, p 705 (2012)
Cell Reports, Vol 2, Iss 2, Pp 321-331 (2012)
Cell Reports, Vol 2, Iss 3, p 705 (2012)
Cell Reports, Vol 2, Iss 2, Pp 321-331 (2012)
Summary Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunit
Autor:
Phillipp Erben, Andreas Reiter, Marie Frickenhaus, Hubert Serve, Christoph Walz, Andreas Hochhaus, Wolf-Karsten Hofmann, Wolfgang E. Berdel, Steffen Koschmieder, Martin Stehling, Christian Elling, Mirle Schemionek, Nicholas C.P. Cross, Carsten Müller-Tidow
Publikováno v:
Blood. 117:2935-2943
The FIP1L1-PDGFRA fusion is seen in a fraction of cases with a presumptive diagnosis of hypereosinophilic syndrome (HES). However, because most HES patients lack FIP1L1-PDGFRA, we studied whether they harbor activating mutations of the PDGFRA gene. S
Publikováno v:
Scientific Reports
To expand the rich genetic toolkit of Drosophila melanogaster, we evaluated whether introducing FRT or LoxP sites in endogenous genes could allow for cell-type-specific gene inactivation in both dividing and postmitotic cells by GAL4-driven expressio
Autor:
Christoph Walz, Mirle Schemionek, Wolfgang E. Berdel, Hubert Serve, Philipp Erben, Marie Frickenhaus, Christian Elling, Carsten Mueller-Tidow, Steffen Koschmieder, Andreas Reiter, Nicholas C.P. Cross, Martin Stehling
Publikováno v:
Web of Science
Abstract 767 Considerable progress has been achieved in our understanding of the pathogenesis of hypereosinophilic syndrome (HES) and chronic eosinophilic leukemia (CEL) by identification of constitutively activated tyrosine kinase fusion genes, e.g.