Výsledky vyhledávání - "Marie F. LaRussa"

Akademický článek

Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.

Autor: Zhen Wang, Misha C Tran, Namrata J Bhatia, Alexander W Hsing, Carol Chen, Marie F LaRussa, Ernst Fattakhov, Vania Rashidi, Kyu Yun Jang, Kevin J Choo, Xingju Nie, Jonathan A Mathy, Michael T Longaker, Reinhold H Dauskardt, Jill A Helms, George P Yang

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160684 (2016)

OBJECTIVE:We identified significant expression of the matricellular protein, DEL1, in hypertrophic and mature cartilage during development. We hypothesized that this tissue-specific expression indicated a biological role for DEL1 in cartilage biology

Externí odkaz: https://doaj.org/article/8ea7d17c343e438e9a382bd55afff848

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DEL1 protects against chondrocyte apoptosis through integrin binding

Autor: George P. Yang, Tatiana Boyko, Namrata Bhatia, Vania Rashidi, Michael T. Longaker, Marie F. LaRussa, Misha C. Tran, Zhen Wang

Publikováno v: Journal of Surgical Research. 231:1-9

Background Osteoarthritis (OA) is a debilitating disease process, affecting mobility and overall health of millions. Current treatment is for symptomatic relief and discovery of approaches to halt or reverse damage is imperative. Deletion of developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a46a9349039278efebaa127d176bc4
https://doi.org/10.1016/j.jss.2018.04.066

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Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis

Autor: Reinhold H. Dauskardt, Marie F. LaRussa, Michael T. Longaker, E. Fattakhov, Vania Rashidi, Kyu Yun Jang, A. W. Hsing, Misha C. Tran, Carol Chen, Zhen Wang, Namrata Bhatia, Jill A. Helms, Kevin J. Choo, Xingju Nie, Jonathan A. Mathy, George P. Yang

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160684 (2016)

Objective We identified significant expression of the matricellular protein, DEL1, in hypertrophic and mature cartilage during development. We hypothesized that this tissue-specific expression indicated a biological role for DEL1 in cartilage biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e47795f580b9a06f0a245ce1108158
https://pubmed.ncbi.nlm.nih.gov/27505251

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Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming

Autor: Ronald J. Parchem, Julia Ye, Robert L. Judson, Robert Blelloch, Michael C. Oldham, Raga Krishnakumar, Marie F. LaRussa, Amy Blelloch

Publikováno v: Cell stem cell, vol 14, iss 5
Parchem, RJ; Ye, J; Judson, RL; Larussa, MF; Krishnakumar, R; Blelloch, A; et al.(2014). Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell, 14(5), 617-631. doi: 10.1016/j.stem.2014.01.021. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6mz2x1br

Ectopic expression of specific factors such as Oct4, Sox2, and Klf4 (OSK) is sufficient to reprogram somatic cells into induced pluripotent stem cells (iPSCs). In this study, we examine the paths taken by cells during the reprogramming process by fol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef88a08298011c0956f85fcc810d025

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