Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Marie E. Oskarsson"'
Autor:
Anna Rising, Paola Gherardi, Gefei Chen, Jan Johansson, Marie E. Oskarsson, Gunilla T. Westermark, Per Westermark
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Abstract AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one
Externí odkaz:
https://doaj.org/article/e6504fa2eb8649faab412890a3a44365
Publikováno v:
Upsala Journal of Medical Sciences, Vol 122, Iss 3, Pp 149-159 (2017)
Background: Enhanced IAPP production may contribute to islet amyloid formation in type 2 diabetes. The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human β-cells. Methods: EndoC-βH1 ce
Externí odkaz:
https://doaj.org/article/751f7d8d553644e18cb9885e22949afe
Autor:
Sara Ullsten, Sara Bohman, Marie E Oskarsson, K Peter R Nilsson, Gunilla T Westermark, Per-Ola Carlsson
Publikováno v:
Endocrine Connections, Vol 6, Iss 7, Pp 458-468 (2017)
Islet amyloid and beta cell death in type 2 diabetes are heterogeneous events, where some islets are affected early in the disease process, whereas others remain visibly unaffected. This study investigated the possibility that inter-islet functional
Externí odkaz:
https://doaj.org/article/96a24516c7114072b89f9897f9232a8a
Autor:
Pascal Krotee, Jose A Rodriguez, Michael R Sawaya, Duilio Cascio, Francis E Reyes, Dan Shi, Johan Hattne, Brent L Nannenga, Marie E Oskarsson, Stephan Philipp, Sarah Griner, Lin Jiang, Charles G Glabe, Gunilla T Westermark, Tamir Gonen, David S Eisenberg
Publikováno v:
eLife, Vol 6 (2017)
hIAPP fibrils are associated with Type-II Diabetes, but the link of hIAPP structure to islet cell death remains elusive. Here we observe that hIAPP fibrils are cytotoxic to cultured pancreatic β-cells, leading us to determine the structure and cytot
Externí odkaz:
https://doaj.org/article/f0207c5ac18e49debe0019586fe78051
Autor:
Paola Gherardi, Jan Johansson, Gefei Chen, Gunilla T. Westermark, Per Westermark, Anna Rising, Marie E. Oskarsson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-5 (2021)
AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one kind of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70a974b2edc1085ba219bd50fab2124
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459015
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459015
Publikováno v:
Upsala Journal of Medical Sciences, Vol 122, Iss 3, Pp 149-159 (2017)
Upsala Journal of Medical Sciences
Upsala Journal of Medical Sciences
Background: Enhanced IAPP production may contribute to islet amyloid formation in type 2 diabetes. The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human β-cells. Methods: EndoC-βH1 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67e1ce25dc05a9689d648487fe532f1
https://doaj.org/article/751f7d8d553644e18cb9885e22949afe
https://doaj.org/article/751f7d8d553644e18cb9885e22949afe
Autor:
Per Westermark, Marie E. Oskarsson, Sebastian W. Schultz, Martin Ingelsson, Gunilla T. Westermark, Johan Paulsson
Publikováno v:
The American Journal of Pathology. 185:834-846
Several proteins have been identified as amyloid forming in humans, and independent of protein origin, the fibrils are morphologically similar. Therefore, there is a potential for structures with amyloid seeding ability to induce both homologous and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c246da698c5f6a1d0fffdf6eb74f69c5
https://doi.org/10.1016/j.ajpath.2014.11.016
https://doi.org/10.1016/j.ajpath.2014.11.016
Autor:
David Eisenberg, Pascal Krotee, Stephan Philipp, Michael R. Sawaya, Jose A. Rodriguez, Tamir Gonen, Marie E. Oskarsson, Gunilla T. Westermark, Duilio Cascio, Sarah Griner, Dan Shi, Charles G. Glabe, Brent L. Nannenga, Francis E. Reyes, Johan Hattne, Lin Jiang
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
hIAPP fibrils are associated with Type-II Diabetes, but the link of hIAPP structure to islet cell death remains elusive. Here we observe that hIAPP fibrils are cytotoxic to cultured pancreatic β-cells, leading us to determine the structure and cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad9cbcca775396d40dce43913666132
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316042
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-316042
Autor:
Michael R. Sawaya, Lin Jiang, Stephan Philipp, Sarah Griner, Jose A. Rodriguez, David Eisenberg, Dan Shi, Gunilla T. Westermark, Pascal Krotee, Charles G. Glabe, Duilio Cascio, Marie E. Oskarsson, Tamir Gonen, Johan Hattne, Francis E. Reyes, Brent L. Nannenga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f2ff67c8a0d43506d6d2be6f7e6dc50
https://doi.org/10.7554/elife.19273.026
https://doi.org/10.7554/elife.19273.026
Autor:
Marie E. Oskarsson, Gunilla T. Westermark, Pascal Krotee, Michael R. Sawaya, Jose A. Rodriguez, Johan Hattne, Tamir Gonen, Francis E. Reyes, Dan Shi, David Eisenberg, Lin Jiang, Duilio Cascio, Brent L. Nannenga
Publikováno v:
Biophysical Journal. 112:14a
The Cryo-EM Method Micro-ED Structure Determination of Type II Diabetes-Related Protein Segments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb43b0dc6e4ef7342e017ef73719947
https://doi.org/10.1016/j.bpj.2016.11.110
https://doi.org/10.1016/j.bpj.2016.11.110