Investigating the role of early childhood abuse and HPA axis genes in suicide attempters with bipolar disorder

Autor: Fayaz Seifuddin, Virginia L. Willour, Marie E. Breen, Peter P. Zandi, James B. Potash

Publikováno v: Psychiatric Genetics. 25:106-111

OBJECTIVE: Genes and the environment both play a major role in the risk for attempted suicide, and environments harboring stressors, such as early childhood abuse, have been linked to suicidal behavior. Such environments also disrupt the hypothalamic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf2a471c66e077b6f2c470d98ace44d
https://doi.org/10.1097/ypg.0000000000000082

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

Autor: Doris Lechner, Miriam Capri, Stefan Böhringer, Stefan Schreiber, Gonneke Willemsen, Paolo Garagnani, Irene Maeve Rea, Andres Metspalu, Palmi V. Jonsson, Thomas B. L. Kirkwood, Lene Christiansen, Fernando Rivadeneira, Giuseppina Rose, J. Wouter Jukema, Serena Dato, Owen A. Ross, Almut Nebel, Cornelia M. van Duijn, Gary Saunders, Bernard Jeune, David J. Stott, Jeanine J. Houwing-Duistermaat, A. Murphy, Anton J. M. de Craen, Friederike Flachsbart, Karen Andersen-Ranberg, Albert Hofman, Ian Ford, Ellen A. Nohr, Giuseppe Passarino, Krista Fischer, Elisa Cevenini, Carmen Martin-Ruiz, Jutta Gampe, Iris Postmus, Christopher P. Nelson, Stefano Salvioli, Alberto Montesanto, Mark Lathrop, Marianne Nygaard, Marie E. Breen, Jennifer Harrow, Hae-Won Uh, Erik B. van den Akker, Thorkild I. A. Sørensen, André G. Uitterlinden, Alexander Viktorin, Bastiaan T. Heijmans, Susan E. McNerlan, Quinta Helmer, Naveed Sattar, Claudio Franceschi, Eco J. C. de Geus, E. Mihailov, Jouke-Jan Hottenga, Qihua Tan, Kari Stefansson, Yoichiro Kamatani, Paolina Crocco, Henning Tiemeier, Stella Trompet, Patrik K. E. Magnusson, Marian Beekman, Riin Tamm, Amke Caliebe, Maris Alver, Femke-Anouska Heinsen, Pilar Galan, Daníel F. Guðbjartsson, Joris Deelen, Linda Broer, Ruud van der Breggen, Kristin L. Ayers, Anna M. Bennet, Dorret I. Boomsma, P. Eline Slagboom, Kaare Christensen, Diana van Heemst, Joanna Collerton, Karen Davies, Rudi G. J. Westendorp, Hélène Blanché, Lavinia Paternoster, Nilesh J. Samani, Hreinn Stefansson, Simon P. Mooijaart, Heather J. Cordell

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2014, 23 (16), pp.4420-32. ⟨10.1093/hmg/ddu139⟩
Human Molecular Genetics, 23(16), 4420-4432. Oxford University Press
Human Molecular Genetics; Vol 23
Hum Mol Genet
Deelen, J, Beekman, M, Uh, H-W, Broer, L, Ayers, K L, Tan, Q, Kamatani, Y, Bennet, A M, Tamm, R, Trompet, S, Guðbjartsson, D F, Flachsbart, F, Rose, G, Viktorin, A, Fischer, K, Nygaard, M, Cordell, H J, Crocco, P, van den Akker, E B, Böhringer, S, Helmer, Q, Nelson, C P, Saunders, G I, Alver, M, Anderson-Ranberg, K, Breen, M E, van der Breggen, R, Caliebe, A, Capri, M, Cevenini, E, Collerton, J C, Dato, S, Davies, K, Ford, I, Gampe, J, Garagnani, P, de Geus, E J C, Harrow, J, van Heemst, D, Heijmans, B T, Heinsen, F-A, Hottenga, J-J, Hofman, A, Juene, B, Jonsson, P V, Lathrop, M, Lechner, D, Martin-Ruiz, C, Mcnerlan, S E, Mihailov, E, Montesanto, A, Mooijaart, S P, Murphy, A, Nohr, E A, Paternoster, L, Postmus, I, Rivadeneira, F, Ross, O A, Salvioli, S, Sattar, N, Schreiber, S, Stefánsson, H, Stott, D J, Tiemeier, H, Uitterlinden, A G, Westendorp, R G J, Willemsen, G, Samani, N J, Galan, P, Sørensen, T I A, Boomsma, D I, Jukema, J W, Rea, I M, Passarino, G, de Craen, A J M, Christensen, K, Nebel, A, Stefánsson, K, Metspalu, A, Magnusson, P, Blanché, H, Christiansen, L, Kirkwood, T B L, van Duijn, C M, Franceschi, C, Houwing-Duistermaat, J J & Slagboom, P E 2014, ' Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age ', Human Molecular Genetics, vol. 23, no. 6, pp. 4420-4432 . https://doi.org/10.1093/hmg/ddu139
Deelen, J, Beekman, M, Uh, H-W, Broer, L, Ayers, K L, Tan, Q, Kamatani, Y, Bennet, A M, Tamm, R, Trompet, S, Guðbjartsson, D F, Flachsbart, F, Rose, G, Viktorin, A, Fischer, K, Nygaard, M, Cordell, H J, Crocco, P, van den Akker, E B, Böhringer, S, Helmer, Q, Nelson, C P, Saunders, G I, Alver, M, Andersen-Ranberg, K, Breen, M E, van der Breggen, R, Caliebe, A, Capri, M, Cevenini, E, Collerton, J C, Dato, S, Davies, K, Ford, I, Gampe, J, Garagnani, P, de Geus, E J C, Harrow, J, van Heemst, D, Heijmans, B T, Heinsen, F-A, Hottenga, J-J, Hofman, A, Jeune, B, Jonsson, P V, Lathrop, M, Lechner, D, Martin-Ruiz, C, McNerlan, S E, Mihailov, E, Montesanto, A, Mooijaart, S P, Murphy, A, Nohr, E A, Paternoster, L, Postmus, I, Rivadeneira, F, Ross, O A, Salvioli, S, Sattar, N, Schreiber, S, Stefánsson, H, Stott, D J, Tiemeier, H, Uitterlinden, A G, Westendorp, R G J, Willemsen, G, Samani, N J, Galan, P, Sørensen, T I A, Boomsma, D I, Jukema, J W, Rea, I M, Passarino, G, de Craen, A J M, Christensen, K, Nebel, A, Stefánsson, K, Metspalu, A, Magnusson, P, Blanché, H, Christiansen, L, Kirkwood, T B L, van Duijn, C M, Franceschi, C, Houwing-Duistermaat, J J & Slagboom, P E 2014, ' Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age ', Human Molecular Genetics, vol. 23, no. 16, ddu139, pp. 4420-4432 . https://doi.org/10.1093/hmg/ddu139
Human Molecular Genetics, 23(16), 4420-4432
Deelen, J, Beekman, M, Uh, H W, Broer, L, Ayers, K L, Tan, Q, Kamatani, Y, Bennet, A M, Tamm, R, Trompet, S, Gudbjartsson, D F, Flachsbart, F, Rose, G, Viktorin, A, Fischer, K, Nygaard, M, Cordell, H J, Crocco, P, van den Akker, E B, Böhringer, S, Helmer, Q, Nelson, C P, Saunders, G I, Alver, M, Andersen-Ranberg, K, Breen, M E, van der Breggen, R, Caliebe, A, Capri, M, Cevenini, E, Collerton, J C, Dato, S, Davies, K, Ford, I, Gampe, J, Garagnani, P, de Geus, E J C, Harrow, J, van Heemst, D, Heijmans, B T, Heinsen, F A, Hottenga, J J, Hofman, A, Jeune, B, Jonsson, P V, Lathrop, M, Lechner, D, Martin-Ruiz, C, McNerlan, S E, Mihailov, E, Montesanto, A, Mooijaart, S P, Murphy, A, Nohr, E A, Paternoster, L, Postmus, I, Rivadeneira, F, Ross, O A, Salvioli, S, Sattar, N, Schreiber, S, Stefansson, H, Stott, D J, Tiemeier, H, Uitterlinden, A G, Westendorp, R G J, Willemsen, G, Samani, N J, Galan, P, Sørensen, T I A, Boomsma, D I, Jukema, J W, Maeve Rea, I, Passarino, G, de Craen, A J, Christensen, K, Nebel, A, Stefansson, K, Metspalu, A, Magnusson, P, Blanché, H, Christiansen, L, Kirkwood, T B L, van Duijn, C M, Franceschi, C, Houwing-Duistermaat, J J & Slagboom, P E 2014, ' Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age ', Human Molecular Genetics, vol. 23, no. 16, pp. 4420-4432 . https://doi.org/10.1093/hmg/ddu139

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