Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Marie Daoud-El Baba"'
Autor:
Ryosuke Kojima, Daniel Bojar, Giorgio Rizzi, Ghislaine Charpin-El Hamri, Marie Daoud El-Baba, Pratik Saxena, Simon Ausländer, Kelly R. Tan, Martin Fussenegger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Exosomes function as intercellular information transmitters and are candidates for delivery of therapeutic agents. Here the authors present EXOtic, a synthetic biology device for in-situ production of designer exosomes and demonstrate in vivo applica
Externí odkaz:
https://doaj.org/article/0e6a2ce92e194d368bbcb60650f4592b
Autor:
Daniel Bojar, Marie Daoud El-Baba, Simon Ausländer, Ghislaine Charpin-El Hamri, Kelly R. Tan, Ryosuke Kojima, Giorgio Rizzi, Pratik Saxena, Martin Fussenegger
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, 9 (1)
Nature Communications, 9 (1)
Exosomes are cell-derived nanovesicles (50–150 nm), which mediate intercellular communication, and are candidate therapeutic agents. However, inefficiency of exosomal message transfer, such as mRNA, and lack of methods to create designer exosomes h
Autor:
Pascal Tomakidi, Philipp Eberwein, Marie Daoud El-Baba, Ghislaine Charpin-El Hamri, Dougal Laird, Katja Nelson, Thorsten Steinberg
Publikováno v:
Journal of Bioactive and Compatible Polymers. 30:319-339
In vitro and in vivo biocompatibility evaluation of medical devices designed for soft tissue healing and regeneration is mandatory for new biomaterials targeted toward human application. To this end, a novel stimulus-responsive eight-arm poly(ethylen
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 35 (17)
Nucleic Acids Research, 35 (17)
Nucleic Acids Research, 35 (17)
ISSN:1362-4962
ISSN:0301-5610
ISSN:1362-4962
ISSN:0301-5610
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f19ccfed02c9c114ad3612c97f0cccf
http://doc.rero.ch/record/302507/files/gkm466.pdf
http://doc.rero.ch/record/302507/files/gkm466.pdf
Autor:
Hanna Seitz, Martin Werner, Ghislaine Charpin-El Hamri, Balder Rebmann, Wilfried Weber, Ronald Schoenmakers, Raphael J. Gübeli, Martin Ehrbar, Marie Daoud-El Baba, Désirée Hövermann, Martin Müller
Publikováno v:
Advanced Functional Materials. 23:5355-5362
Remote-controlled drug depots represent a highly valuable tool for the timely controlled administration of pharmaceuticals in a patient compliant manner. Here, the first pharmacologically controlled material that allows for the scheduled induction of
Autor:
Valentin Djonov, Martin Fussenegger, Christian Kemmer, Marie Daoud-El Baba, Marc Gitzinger, Jörg Stelling
Publikováno v:
Nature biotechnology
Synthetic biology has shown that the metabolic behavior of mammalian cells can be altered by genetic devices such as epigenetic and hysteretic switches, timers and oscillators, biocomputers, hormone systems and heterologous metabolic shunts. To explo
Publikováno v:
Proceedings of the National Academy of Sciences. 106:10638-10643
Adjustable control of therapeutic transgenes in engineered cell implants after transdermal and topical delivery of nontoxic trigger molecules would increase convenience, patient compliance, and elimination of hepatic first-pass effect in future thera
Autor:
Thomas Grau, Marc Gitzinger, Peter Sander, Marie Daoud-El Baba, Martin Fussenegger, Wilfried Weber, Ronald Schoenmakers, Bettina G. Keller
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Synthetic biology provides insight into natural gene-network dynamics and enables assembly of engineered transcription circuitries for production of difficult-to-access therapeutic molecules. In Mycobacterium tuberculosis EthR binds to a specific ope
Autor:
Martin Fussenegger, Jörg Stelling, Bettina G. Keller, Markus Rimann, Cornelia C. Weber, Dominique Aubel, Marie Daoud-El Baba, Wilfried Weber
Publikováno v:
Proceedings of the National Academy of Sciences. 104:2643-2648
Time-delay circuitries in which a transcription factor processes independent input parameters can modulate NF-κB activation, manage quorum-sensing cross-talk, and control the circadian clock. We have constructed a synthetic mammalian gene network th
Publikováno v:
Biotechnology and Bioengineering. 98:655-667
Mammalian reporter proteins are essential for gene-function analysis, drugscreening initiatives and as model product proteins for biopharmaceutical manufacturing. Bacillus subtilis can maintain its metabolism by secreting Xylanase A (XynA), which con