Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Marie Cumberbatch"'
Autor:
Marie Cumberbatch, Ying Qu, Aaron Mayer, Milan Bhagat, Steve Hamel, Alexandro E Trevino, Meredith Manuel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/3df60aea2c514fa29ae28402396fd4d2
Autor:
Edmund Poon, Stefanie Mullins, Amanda Watkins, Geoffrey S. Williams, Jens-Oliver Koopmann, Gianfranco Di Genova, Marie Cumberbatch, Margaret Veldman-Jones, Shaun E. Grosskurth, Vasu Sah, Alwin Schuller, Corrine Reimer, Simon J. Dovedi, Paul D. Smith, Ross Stewart, Robert W. Wilkinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-14 (2017)
Abstract Background T-cell checkpoint blockade and MEK inhibitor combinations are under clinical investigation. Despite progress elucidating the immuno-modulatory effects of MEK inhibitors as standalone therapies, the impact of MEK inhibition on the
Externí odkaz:
https://doaj.org/article/10af9c0a04c24ff1aad8329f36522589
Autor:
James Monkman, Honesty Kim, Aaron Mayer, Ahmed Mehdi, Nicholas Matigian, Marie Cumberbatch, Milan Bhagat, Rahul Ladwa, Scott N. Mueller, Mark N. Adams, Ken O'Byrne, Arutha Kulasinghe
Publikováno v:
Immunology.
Autor:
Stephen Green, Francisco Cruzalegui, Lara Ward, Sabina C. Cosulich, Marie Cumberbatch, Alys Jones, Rebecca Ellston, Lyndsey Hanson, Phillippa Dudley, Oona Delpuech, Alvaro Avivar-Valderas, Pablo Morentin Gutierrez, Myria Nikolaou, Urszula M. Polanska, Robert McEwen, Cath Trigwell, Urs J. Hancox, Kevin Hudson
Tumor cell line panel composition and growth inhibition sensitivity (GI50) to AZD8835.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4782fd316b02ec8951d691e4f7122f
https://doi.org/10.1158/1535-7163.22507675.v1
https://doi.org/10.1158/1535-7163.22507675.v1
Autor:
Stephen Green, Francisco Cruzalegui, Lara Ward, Sabina C. Cosulich, Marie Cumberbatch, Alys Jones, Rebecca Ellston, Lyndsey Hanson, Phillippa Dudley, Oona Delpuech, Alvaro Avivar-Valderas, Pablo Morentin Gutierrez, Myria Nikolaou, Urszula M. Polanska, Robert McEwen, Cath Trigwell, Urs J. Hancox, Kevin Hudson
Details on PK / PD / efficacy modeling in BT474 xenograft model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c1af759ac8bbaffa0a90dd3c7be5a7
https://doi.org/10.1158/1535-7163.22507681
https://doi.org/10.1158/1535-7163.22507681
Autor:
Simon T. Barry, Francisco Cruzalegui, Susan E. Critchlow, Teresa Klinowska, Marie Cumberbatch, Alvaro Avivar-Valderas, Radoslaw Polanski, Carol Lenaghan, Catherine Eberlein, Catherine Trigwell, Juliana Maynard, Oona Delpuech, Ursula Hancox, Urszula M. Polanska, James T. Lynch
Supp Fig 1 Tumour efficacy Supp Fig 2 In vitro gene expression modulation Supp Fig 3 In vivo biomarker analysis Supp Fig 4 HCC70 In vivo FDG uptake imaging Supp Fig 5 U87MG in vivo FDG uptake imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a49696169a1bdafab82b251d9a41f65
https://doi.org/10.1158/1535-7163.22505517.v1
https://doi.org/10.1158/1535-7163.22505517.v1
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 56KB, Supplementary methods detailing Relative peptide quantification by selected reaction monitoring (SRM)using mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d12f691841ae5003bde43d483fc498
https://doi.org/10.1158/1535-7163.22500958
https://doi.org/10.1158/1535-7163.22500958
Autor:
A. Nigel Brooks, Stephen R. Wedge, Susan E. Critchlow, Craig N. Robson, Simon T. Barry, Chris Womack, Luke Gaughan, Alfred Rabow, Robert H. Bradbury, Rhys D.O. Jones, Joanne Wilson, Marie Cumberbatch, Vivien N. Jacobs, Fadhel S. Shaheen, Elizabeth Mouchet, Dawn Trueman, Natalie C. Stratton, Nicola Broadbent, Sandra R. Brave, Tom P.J. Dunkley, Graeme E. Walker, David M. Robinson, Andrew G. Thomason, Sarah J. Ross, Sarah A. Loddick
PDF - 464KB, Supplementary Figure 1: Inhibition of AR transcripts with AZD3514 treated LNCaPs in steroid free media and the timecourse of AZD3514 effects in the presence and absence of DHT. Supplementary Figure 2: Effect of AZD3514 on growth of AR ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d194c3a51c866f292b69afd928b73e
https://doi.org/10.1158/1535-7163.22500961
https://doi.org/10.1158/1535-7163.22500961
Autor:
Simon T. Barry, Stephen Green, Marie Cumberbatch, Emily Foster, Elizabeth A. Harrington, Barry R. Davies, Mandy Lawson, Steve Powell, Lara Ward, Stephen R. Wedge, Lillian Castriotta, Celina D'Cruz, Donald Ogilvie, Paul D. Smith, Martina Fitzek, Bernard Barlaam, Claire Crafter, Hannah Dry, Rebecca Ellston, Carol Lenaghan, Cath Trigwell, Lyndsey Hanson, Sabina Cosulich, Urs Hancox
Supplementary Materials text. Supplementary text to support supplementary data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc9bdcf5800ec6832230c58fa50deb2
https://doi.org/10.1158/1535-7163.22502410.v1
https://doi.org/10.1158/1535-7163.22502410.v1
Autor:
Simon T. Barry, Stephen Green, Marie Cumberbatch, Emily Foster, Elizabeth A. Harrington, Barry R. Davies, Mandy Lawson, Steve Powell, Lara Ward, Stephen R. Wedge, Lillian Castriotta, Celina D'Cruz, Donald Ogilvie, Paul D. Smith, Martina Fitzek, Bernard Barlaam, Claire Crafter, Hannah Dry, Rebecca Ellston, Carol Lenaghan, Cath Trigwell, Lyndsey Hanson, Sabina Cosulich, Urs Hancox
Supplementary Tables 1-3 and Figure 1-7. Supp Table 1 Summary of cell line origins and verification. Supp Table 2 Summary of antibodies used in all experimental analysis Supp Fig 1 AZD8186 inhibits PI3K pathway in PTEN null but not PTEN WT PIKC3A MT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1480195d4ae54dd467c3ee5679efbedf
https://doi.org/10.1158/1535-7163.22502407.v1
https://doi.org/10.1158/1535-7163.22502407.v1