Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Marie Claude Faugere"'
Autor:
Naomi Dirckx, Qian Zhang, Emily Y. Chu, Robert J. Tower, Zhu Li, Shenghao Guo, Shichen Yuan, Pratik A. Khare, Cissy Zhang, Angela Verardo, Lucy O. Alejandro, Angelina Park, Marie-Claude Faugere, Stephen L. Helfand, Martha J. Somerman, Ryan C. Riddle, Rafael de Cabo, Anne Le, Klaus Schmidt-Rohr, Thomas L. Clemens
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Citrate is a critical metabolic substrate and key regulator of energy metabolism in mammalian cells. It has been known for decades that the skeleton contains most (>85%) of the body’s citrate, but the question of why and how this metabolite should
Autor:
Amr El-Husseini, Mohamed Abdalbary, Florence Lima, Daniel Davenport, Marie-Claude Faugere, Hartmut H. Malluche
Publikováno v:
Kidney international reports. 7(6)
Autor:
Amr El-Husseini, Mohamed Abdalbary, Florence Lima, Mohamed Issa, Mohamed-Tarek Ahmed, Michael Winkler, Habib Srour, Daniel Davenport, Guodong Wang, Marie-Claude Faugere, Hartmut H. Malluche
Publikováno v:
Kidney international reports. 7(5)
Limited information is available on renal osteodystrophy (ROD) and vascular calcification (VC) during early chronic kidney disease (CKD). This study was designed to evaluate ROD and VC in 32 patients with CKD stages II to IV.Patients underwent dual-e
Autor:
Angela R Verardo, Zhu Li, Qian Yang, Robert J. Tower, Naomi Dirckx, Thomas L. Clemens, Charles R. Farber, Gina M. Calabrese, Marie Claude Faugere, Qian Zhang, Larry D. Mesner
Publikováno v:
J Clin Invest
Bone mineral density (BMD) is a highly heritable predictor of osteoporotic fracture. GWAS have identified hundreds of loci influencing BMD, but few have been functionally analyzed. In this study, we show that SNPs within a BMD locus on chromosome 14q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f80de982860f1727e3ed6e63681732b
https://europepmc.org/articles/PMC8011892/
https://europepmc.org/articles/PMC8011892/
Autor:
Ryan C Riddle, Cassandra R Diegel, Julie M Leslie, Kyle K Van Koevering, Marie-Claude Faugere, Thomas L Clemens, Bart O Williams
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63323 (2013)
The canonical Wnt signaling pathway is critical for skeletal development and maintenance, but the precise roles of the individual Wnt co-receptors, Lrp5 and Lrp6, that enable Wnt signals to be transmitted in osteoblasts remain controversial. In these
Externí odkaz:
https://doaj.org/article/f800c6322c8f4019a916fd0d6a4d0983
Publikováno v:
Case Reports in Endocrinology, Vol 2020 (2020)
Case Reports in Endocrinology
Case Reports in Endocrinology
We describe a case of hereditary hypophosphatemic rickets with hypercalciuria (HHRH) in a 32-year-old female with short stature, chronic pathologic genu valgum deformity, and knee pain who was referred to endocrinology clinic after previous inconclus
Autor:
Olga A. Agapova, Joseph P. Gaut, Matthew Williams, Toshifumi Sugatani, Marie Claude Faugere, Keith A. Hruska, Yifu Fang, Hartmut H. Malluche
Publikováno v:
Kidney International. 93:147-158
We examined activin receptor type IIA (ActRIIA) activation in chronic kidney disease (CKD) by signal analysis and inhibition in mice with Alport syndrome using the ActRIIA ligand trap RAP-011 initiated in 75-day-old Alport mice. At 200 days of age, t
Autor:
Ryan E. Tomlinson, Marie Claude Faugere, Angelica J. Herrera, Brian C. Goh, Vandana Singhal, Se-Jin Lee, Douglas J. DiGirolamo, Thomas L. Clemens, Emily L. Germain-Lee, Soo-Hyun Kim
Publikováno v:
Journal of Biological Chemistry. 292:13809-13822
Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks that coordinate the development of these two anatomically adjacent tissues. The activin signaling pathway is an attractive
Autor:
Clifford R. Rosen, Thomas L. Clemens, Ryan C. Riddle, Denis C. Guttridge, Naomi Dirckx, Charles R. Farber, Qian Yang, Marie Claude Faugere, Qian Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(36)
The fat mass and obesity-associated gene (FTO) encodes an m6A RNA demethylase that controls mRNA processing and has been linked to both obesity and bone mineral density in humans by genome-wide association studies. To examine the role of FTO in bone,
Autor:
Stuart L. Mitchell, Paul D. Sponseller, Ryan E. Tomlinson, Harry C. Dietz, Brian C. Goh, Eric W. Tan, Marie Claude Faugere, Rachel M. Yung, Thomas L. Clemens, Sarvesh Kumar, Ashvin K. Dewan
Publikováno v:
Journal of Orthopaedic Research. 33:1447-1454
Loeys-Dietz syndrome (LDS) is a connective tissue disorder characterized by vascular and skeletal abnormalities resembling Marfan syndrome, including a predisposition for pathologic fracture. LDS is caused by heterozygous mutations in the genes encod