Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics.

Autor: Marie Chion, Christine Carapito, Frédéric Bertrand

Publikováno v: PLoS Computational Biology, Vol 18, Iss 8, p e1010420 (2022)

Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the imputation proces

Externí odkaz: https://doaj.org/article/291ee1a22e624efab92f8e83695ef083

Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics

Autor: Marie Chion, Christine Carapito, Frédéric Bertrand

Publikováno v: PLoS Computational Biology
PLoS Computational Biology, 2022, 18 (8), pp.e1010420. ⟨10.1371/journal.pcbi.1010420⟩

Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the imputation proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c7f6571224c95332cefe52ac06fbf5
http://arxiv.org/abs/2108.07086

Combining label-free and label-based accurate quantifications with SWATH-MS: Comparison with SRM and PRM for the evaluation of bovine muscle type effects

Autor: Brigitte Picard, Frédéric Bertrand, Joanna Bons, Muriel Bonnet, Christine Carapito, Sarah Cianférani, Marie Chion, François Delalande, Gauthier Husson, Myriam Maumy-Bertrand

Publikováno v: Proteomics
Proteomics, 2021, 21 (10), pp.2000214. ⟨10.1002/pmic.202000214⟩
Proteomics, Wiley-VCH Verlag, 2021, pp.2000214. ⟨10.1002/pmic.202000214⟩
Proteomics, Wiley-VCH Verlag, 2021, 21 (10), pp.2000214. ⟨10.1002/pmic.202000214⟩

International audience; Mass spectrometry has proven to be a valuable tool for the accurate quantification of proteins. In this study, the performances of three targeted approaches, namely selected reaction monitoring (SRM), parallel reaction monitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89d6bc804b4865a025f024be84ddb11
https://pubmed.ncbi.nlm.nih.gov/33733615

Dealing with imputation-caused variance using moderated t-test

Autor: Marie Chion, Christine Carapito, Frédéric Bertrand

Publikováno v: User! 2020
User! 2020, Jul 2020, Saint Louis (cancelled), United States
HAL

Cancelled.; International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8cb5e7f4a394aa70f5acf6baab461b03
https://hal.science/hal-03577610

Extended investigation of tube-gel sample preparation: a versatile and simple choice for high throughput quantitative proteomics

Autor: Thierry Rabilloud, Marie Chion, Leslie Muller, Alain Van Dorsselaer, Luc Fornecker, Christine Carapito, Sarah Cianférani

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.8260. 〈10.1038/s41598-018-26600-4〉
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.8260. ⟨10.1038/s41598-018-26600-4⟩
Scientific Reports, 2018, 8 (1), pp.8260. ⟨10.1038/s41598-018-26600-4⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)

Sample preparation for quantitative proteomics is a crucial step to ensure the repeatability and the accuracy of the results. However, there is no universal method compatible with the wide variety of protein extraction buffers currently used. We have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33340463afbd2633fd8436820a1f832
https://hal.archives-ouvertes.fr/hal-01807209