Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marie Charrel-Dennis"'
Autor:
Marie Charrel-Dennis, Brian A. Cobb, Kathleen J. Zaleski, Douglas T. Golenbock, Arthur O. Tzianabos, Dennis L. Kasper, Qun Wang, Rachel M. McLoughlin
Publikováno v:
The Journal of Experimental Medicine
Commensalism is critical to a healthy Th1/Th2 cell balance. Polysaccharide A (PSA), which is produced by the intestinal commensal Bacteroides fragilis, activates CD4+ T cells, resulting in a Th1 response correcting the Th2 cell skew of germ-free mice
Autor:
Peter J. Delves, A M Jackson, Peter Berger, Ivan M Roitt, Marie Charrel-Dennis, Torben Lund, Adrian J. Lapthorn
Publikováno v:
Journal of Molecular Endocrinology. 32:571-581
The hormone human chorionic gonadotrophin (hCG) shows extensive sequence homology with LH. Thus, many of the antigenic epitopes on hCG are shared with LH, leading to immunological cross-reaction between these two hormones. Anti-fertility and anti-can
Autor:
Veit Hornung, Andrea Ablasser, Katherine A. Fitzgerald, Franz Bauernfeind, Marie Charrel-Dennis, Daniel R. Caffrey, Eicke Latz, Gabor Horvath
Publikováno v:
Nature
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA is sensed by Toll-like receptor members TLR3, TLR7 and TLR8, or by the RNA helicases RIG-I (also known as DDX58) and MDA-5 (IFIH1). Little is known a
Autor:
Kristen A. Halmen, Katherine A. Fitzgerald, Eicke Latz, Marie Charrel-Dennis, Patrick Trieu-Cuot, Douglas T. Golenbock, Dennis L. Kasper
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2008, 4 (6), pp.543-54. ⟨10.1016/j.chom.2008.11.002⟩
Cell Host and Microbe, 2008, 4 (6), pp.543-54. ⟨10.1016/j.chom.2008.11.002⟩
Cell Host and Microbe, Elsevier, 2008, 4 (6), pp.543-54. ⟨10.1016/j.chom.2008.11.002⟩
Cell Host and Microbe, 2008, 4 (6), pp.543-54. ⟨10.1016/j.chom.2008.11.002⟩
International audience; Type I interferon (IFN) is an important host defense cytokine against intracellular pathogens, mainly viruses. In assessing IFN production in response to group B streptococcus (GBS), we find that IFN-beta was produced by macro
Autor:
Charles Kelly, Jeffrey D. McBride, Marie Charrel-Dennis, Pia M. Martensen, Just Justesen, Adrian J. Lapthorn, Nadia Terrazzini, Ivan M. Roitt, Paul Kaye, Peter Berger, Peter J. Delves, Torben Lund
Publikováno v:
Charrel-Dennis, M, Terrazzini, N, McBride, J D, Kaye, P, Martensen, P M, Justesen, J, Berger, P, Lapthorn, A, Kelly, C, Roitt, I M, Delves, P J & Lund, T 2005, ' The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide ', Molecular Endocrinology, vol. 19, no. 7, pp. 1803-11 . https://doi.org/10.1210/me.2004-0109
Wild-type human chorionic gonadotropin (hCG) has been used as a contraceptive vaccine. However, extensive sequence homology with LH elicits production of cross-reactive antibodies. Substitution of arginine(68) of the beta-subunit (hCG(beta)) with glu