Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marie C. Keenan"'
Autor:
Kristen L Jones, Jeremy H. Tchaicha, Esra A. Akbay, Sushma Gurumurthy, Haikuo Zhang, Sung Choe, Philip C. Amrein, Julian Carretero, Andrew L. Kung, Wei Liu, Javid Moslehi, Camelia Gliser, Kwok-Kin Wong, Katharine E. Yen, Sudeshna Fisch, Stuart Murray, Eiki Kikuchi, Shakti Ramkissoon, Omar Abdel-Wahab, Nika N. Danial, Keith L. Ligon, Marie C. Keenan, Travis J. Cohoon, Roderick T. Bronson, Nabeel Bardeesy, Robert F. Padera, Kazumasa Uno, Amir T. Fathi, Illana A. Stanley, Supriya K. Saha, Kelly M. Stewart, Jaekyoung Son, William G. Kaelin, Julie A. Losman, Alec C. Kimmelman, Camilla L. Christensen, John M. Asara
Publikováno v:
Genesdevelopment. 28(5)
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) have been discovered in several cancer types and cause the neurometabolic syndrome D2-hydroxyglutaric aciduria (D2HGA). The mutant enzymes exhibit neomorphic activity resulting in production of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdf264d176743c92721167be0503cba
https://pubmed.ncbi.nlm.nih.gov/24589777
https://pubmed.ncbi.nlm.nih.gov/24589777
Autor:
William A. Goddard, Linda C. Hsieh-Wilson, Peter M. Clark, Collin Hill, Marie C. Keenan, Edward M. Driggers, Wen Yi, Eric C. Peters, Daniel E. Mason
Publikováno v:
Science (New York, N.Y.). 337(6097)
Metabolic Sensor The enzyme O-GlcNAc transferase (OGT) catalyzes the transfer of N -acetylglucosamine from uridine diphospho- N -acetylglucosamine (UDP-GlcNAc) to serine or threonine residues of intracellular proteins and responds to the metabolic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce73a1fe8d2320e1489c3a6ec62bf02
https://pubmed.ncbi.nlm.nih.gov/22923571
https://pubmed.ncbi.nlm.nih.gov/22923571
Publikováno v:
Journal of Virology. 64:3712-3715
Viral particles purified from species of the protozoan parasite Leishmania braziliensis subsp. guyanensis by centrifugation in CsCl gradients were examined for the presence of viral polymerase. We demonstrated that RNA-dependent RNA polymerase is ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df64f98c6333ec9a39eb2d6c0677db64
https://doi.org/10.1128/jvi.64.8.3712-3715.1990
https://doi.org/10.1128/jvi.64.8.3712-3715.1990
Polyclonal antiserum was raised against the peak viral fraction of a sucrose gradient from LRV1-4-infected cells and used in Western immunoblot analysis to identify viral proteins from various isolates. Consistent with this result, in vitro-translate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ba8d4f975960f674f4bdf32e8d21b9
https://europepmc.org/articles/PMC237969/
https://europepmc.org/articles/PMC237969/
Autor:
Bryson D. Bennett, Lewis C. Cantley, Robert M. Prins, Lenny Dang, Kevin Marks, Valeria Fantin, Joshua D. Rabinowitz, Marie C. Keenan, Shinsan M. Su, Patrick S. Ward, David W. White, Linda M. Liau, Mark A. Bittinger, Shengfang Jin, Katharine E. Yen, Craig B. Thompson, Edward M. Driggers, Stefan Gross, Matthew G. Vander Heiden, Hyun Gyung Jang
Publikováno v:
Nature. 465:966-966
Mutations in the enzyme cytosolic isocitrate dehydrogenase 1 (IDH1) are a common feature of a major subset of primary human brain cancers. These mutations occur at a single amino acid residue of the IDH1 active site, resulting in loss of the enzyme's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c256632f3aa3cb3c5babe2b59d42cd7f
https://doi.org/10.1038/nature09132
https://doi.org/10.1038/nature09132
Publikováno v:
Scopus-Elsevier
Viruses of Leishmania have recently been identified and characterized. These viruses are consistently double-stranded RNA viruses of approximately 5 kb. To date, they have not been reported to exist outside their protozoan host, nor have they been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a983341d5d1db69314b1efdb0ef5f49
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027450798&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0027450798&partnerID=MN8TOARS