Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marie C. Harrisingh"'
Publikováno v:
BMJ (Clinical research ed.). 369
What’s new in this guidance? Venous thromboembolic (VTE) disease is a continuing global health burden with serious mortality, morbidity, and health economic consequences.1 The one year case fatality rate of definite or probable VTE has been estimat
Autor:
Matthew Swire, Tracy J. Yuen, Jacqueline A. Quandt, Henry F. McFarland, Anna Williams, Chao Zhao, Veronique E. Miron, Robin J.M. Franklin, Marie C. Harrisingh, Charles ffrench-Constant, Kory R. Johnson
Publikováno v:
Brain. 136:1035-1047
The development of new regenerative therapies for multiple sclerosis is hindered by the lack of potential targets for enhancing remyelination. The study of naturally regenerative processes such as the innate immune response represents a powerful appr
Autor:
Alison C. Lloyd, Ian J. White, Ilaria Napoli, Ashwin Woodhoo, Luke A. Noon, Laura H. Rosenberg, Marie C. Harrisingh, Simona Parrinello, Ajay P. Kerai, Melissa J. Collins, Sara Ribeiro
Publikováno v:
Neuron. 73:729-742
SummaryFollowing damage to peripheral nerves, a remarkable process of clearance and regeneration takes place. Axons downstream of the injury degenerate, while the nerve is remodeled to direct axonal regrowth. Schwann cells are important for this rege
Publikováno v:
The Journal of Neuroscience. 27:12489-12499
Although circadian oscillation in dynamics of intracellular Ca2+signals has been observed in both plant and animal cells, it has remained unknown whether Ca2+signals play anin vivorole in cellular oscillation itself. To address this question, we modi
Autor:
Alison C. Lloyd, Marie C. Harrisingh
Publikováno v:
Cell Cycle. 3:1255-1258
Ras signalling is important in the development of Schwann-cell-derived tumors in Neurofibromatosis Type 1 (NF1) patients. Schwann cells are a regenerative cell type, with no known stem-cell population. To produce new cells in the adult, for example f
Publikováno v:
Science. 291:872-875
Replicative senescence is thought to be an intrinsic mechanism for limiting the proliferative life-span of normal somatic cells. We show here that rat Schwann cells can be expanded indefinitely in culture while maintaining checkpoints normally lost d
Publikováno v:
Cell Stem Cell. 16(2):113-114
Radiation therapy to the brain is a powerful tool in the management of many cancers, but it is associated with significant and irreversible long-term side effects, including cognitive decline and impairment of motor coordination. Depletion of oligode
Publikováno v:
Science (New York, N.Y.). 320(5878)
The mammalian circadian clockwork is modelled as transcriptional and post-translational feedback loops, whereby circadian genes are periodically suppressed by their protein products. We show that adenosine 3′5′ monophosphate (cAMP) signalling con
Autor:
Marie C, Harrisingh, Alison C, Lloyd
Publikováno v:
Cell cycle (Georgetown, Tex.). 3(10)
Ras signalling is important in the development of Schwann-cell-derived tumors in Neurofibromatosis Type 1 (NF1) patients. Schwann cells are a regenerative cell type, with no known stem-cell population. To produce new cells in the adult, for example f
Publikováno v:
Science. 320:879-880
Models of circadian timekeeping mechanisms in plants, flies, and mammals are expanding to include intracellular small-molecule signals.