Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marie C, Zipser"'
Autor:
Reinhard Dummer, Lars E. French, Jivko Kamarashev, Valérie Enderlin, Marie C. Zipser, Katrin Baumann Conzett, Karin Schad
Purpose: Raf/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK signaling pathway is constitutively activated in melanoma. AZD6244 blocks MEK1/2, inhibiting ERK phosphorylation. We focus on associated cutaneous tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c06db10554bdc2371d51fcade191312
https://doi.org/10.1158/1078-0432.c.6517941.v1
https://doi.org/10.1158/1078-0432.c.6517941.v1
Autor:
Ossia M. Eichhoff, Benedetta Belloni, Phil F. Cheng, Natalie C. Schlegel, Alain Mauviel, Marie C. Zipser, Reinhard Dummer, Delphine Javelaud, Keith S. Hoek, Daniel S. Widmer
Publikováno v:
Pigment Cell & Melanoma Research. 25:343-353
There is growing evidence that the metastatic spread of melanoma is driven not by a linear increase in tumorigenic aggressiveness, but rather by switching back and forth between two different phenotypes of metastatic potential. In vitro these phenoty
Autor:
Ossia M. Eichhoff, Keith S. Hoek, Mai Xu, Marie C. Zipser, Lydia Kriegl, Lionel Larue, Thomas Kirchner, Ashani T. Weeraratna, Laurence Denat, Daniel S. Widmer, Reinhard Dummer
Publikováno v:
Pigment Cell & Melanoma Research. 24:631-642
Recent observations suggest that melanoma cells drive disease progression by switching back and forth between phenotypic states of proliferation and invasion. Phenotype switching has been linked to changes in Wnt signalling, and we therefore looked f
Autor:
Maries van den Broek, Lukas Sommer, Burkhardt Seifert, Reinhard Dummer, Daniela Mihic-Probst, Holger Moch, Gianluca Civenni, Benedetta Belloni, Marie C. Zipser, Anne Walter, Nikita Kobert
Publikováno v:
Cancer research
Human melanoma is composed of distinct cell types reminiscent of neural crest derivatives and contains multipotent cells that express the neural crest stem cell markers CD271(p75NTR) and Sox10. When isolated from solid tumors by using a method that l
Autor:
Reinhard Dummer, Paul D. Smith, Keith S. Hoek, Ossia M. Eichhoff, Darrin Stuart, Paolo Nuciforo, Daniel S. Widmer, Humphrey Gardner, Marie C. Zipser, Weihua Liu, Natalie C. Schlegel, Nicola L. Schoenewolf
Publikováno v:
Pigment Cell & Melanoma Research. 24:326-333
Oncogenic mutations within the MAPK pathway are frequent in melanoma, and targeting of MAPK signaling has yielded spectacular responses in a significant number of patients that last for several months before relapsing. We investigated the effects of
Autor:
J. Bodo, Anthony S.-Y. Leong, Nicola Schönewolf, Reinhard Dummer, Alexandre de la Taille, Pascale Cervera, Druck Reinhardt Druck Basel, Lars E. French, Marjam-Jeanette Barysch, Zhengping Zhuang, Bettina Borisch, Daniel C. Hoessli, Yves Allory, Marie C. Zipser, Maria B. Karpova, Stéphane Culine, Satz Mengensatzproduktion, Eric D. Hsi, Jean-François Fléjou
Publikováno v:
Pathobiology. 78:55-58
Autor:
Marie C, Zipser, Ossia M, Eichhoff, Daniel S, Widmer, Natalie C, Schlegel, Nicola L, Schoenewolf, Darrin, Stuart, Weihua, Liu, Humphrey, Gardner, Paul D, Smith, Paolo, Nuciforo, Reinhard, Dummer, Keith S, Hoek
Publikováno v:
Pigment cell & melanoma research
Oncogenic mutations within the MAPK pathway are frequent in melanoma, and targeting of MAPK signaling has yielded spectacular responses in a significant number of patients that last for several months before relapsing. We investigated the effects of
Autor:
Ashani T. Weeraratna, Ossia M. Eichhoff, Marie C. Zipser, Keith S. Hoek, Daniela Mihic, Reinhard Dummer, Mai Xu
Publikováno v:
Melanoma Research. 20:349-355
To date there is no effective therapy for metastatic melanoma and at the molecular level the disease progression is poorly understood. A recent study by our group led to the development of a novel phenotype switching model for melanoma progression, w
Publikováno v:
European Journal of Dermatology. 20:334-338
The use of laser therapy in the treatment of pigmented lesions is a controversial issue as it can delay melanoma diagnosis and may negatively impact mortality. Few cases of melanoma after laser therapy have been reported. It is still unknown whether
Autor:
Daniel S, Widmer, Phil F, Cheng, Ossia M, Eichhoff, Benedetta C, Belloni, Marie C, Zipser, Natalie C, Schlegel, Delphine, Javelaud, Alain, Mauviel, Reinhard, Dummer, Keith S, Hoek
Publikováno v:
Pigment cellmelanoma research. 25(3)
There is growing evidence that the metastatic spread of melanoma is driven not by a linear increase in tumorigenic aggressiveness, but rather by switching back and forth between two different phenotypes of metastatic potential. In vitro these phenoty