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pro vyhledávání: '"Marie Bellio"'
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 491-499 (2020)
Abstract Phosphoinositides are lipid second messengers regulating in time and place the formation of protein complexes involved in the control of intracellular signaling, vesicular trafficking, and cytoskeleton/membrane dynamics. One of these lipids,
Externí odkaz:
https://doaj.org/article/24657eb7b5c249dfb17ba5286978781d
Publikováno v:
Thrombosis Research.
Autor:
Eric Boilard, Marie Bellio
Publikováno v:
Immunological reviewsREFERENCES. 312(1)
Extracellular vesicles (EVs) are small membrane-bound vesicles released by cells under various conditions. They are found in the extracellular milieu in all biological fluids. As the concentrations, contents, and origin of EVs can change during infla
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 491-499 (2020)
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 491-499 (2020)
Phosphoinositides are lipid second messengers regulating in time and place the formation of protein complexes involved in the control of intracellular signaling, vesicular trafficking, and cytoskeleton/membrane dynamics. One of these lipids, phosphat
Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions
Autor:
Benjamin G. Neel, Philippe Valet, Alexandra Mazharian, Yotis A. Senis, Jun Mori, Bernard Payrastre, Cendrine Cabou, Thomas Edouard, Sophie Voisin, Cédric Garcia, Marie Bellio, Sonia Severin, Armelle Yart
Publikováno v:
Blood. 134:2304-2317
Src homology 2 domain–containing phosphatase 2 (SHP2), encoded by the PTPN11 gene, is a ubiquitous protein tyrosine phosphatase that is a critical regulator of signal transduction. Germ line mutations in the PTPN11 gene responsible for catalytic ga
Autor:
Colin, Valet, Aurelie, Batut, Alicia, Vauclard, Alizee, Dortignac, Marie, Bellio, Bernard, Payrastre, Philippe, Valet, Sonia, Severin
Publikováno v:
Cell reports. 32(1)
Megakaryocytes (MKs) come from a complex process of hematopoietic progenitor maturation within the bone marrow that gives rise to de novo circulating platelets. Bone marrow microenvironment contains a large number of adipocytes with a still ill-defin
Autor:
Anne-Dominique Terrisse, Gaëtan Chicanne, Sonia Severin, Manuella Caux, Marie Bellio, Alicia Vauclard, Marie-Pierre Gratacap, Bernard Payrastre
Publikováno v:
Advances in Biological Regulation. 75:100664
Blood platelets, produced by the fragmentation of megakaryocytes, play a key role in hemostasis and thrombosis. Being implicated in atherothrombosis and other thromboembolic disorders, they represent a major therapeutic target for antithrombotic drug