Výsledky vyhledávání - "Marie B. Marron"

Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4

Autor: Amanda Burnett, David León, Pavlos Progias, Ingrid Gomez, Guillermo Velasco, Mark P. Ariaans, Paul Hellewell, Richard A. Kammerer, Marie B. Marron, Victoria Ridger

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports

Angiopoietins are a family of growth factors that are ligands for the tyrosine kinase receptor, Tie2. Angiopoietin 1 (Ang-1) is agonistic for Tie2, plays a key role in blood vessel maturation and stability and has been shown to possess anti-inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6aabdb084384952f5b7e5bf15fa21c0
https://hdl.handle.net/20.500.12530/39488

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Regulated Proteolytic Processing of Tie1 Modulates Ligand Responsiveness of the Receptor-tyrosine Kinase Tie2

Autor: Hak-Zoo Kim, Jais Kavumkal, Gou Young Koh, Harprit Singh, Nicholas P.J. Brindle, Marie B. Marron, Tariq A. Tahir

Publikováno v: Journal of Biological Chemistry. 282:30509-30517

Regulated ectodomain shedding followed by intramembrane proteolysis has recently been recognized as important in cell signaling and for degradation of several type I transmembrane proteins. The receptor-tyrosine kinase Tie1 is known to undergo ectodo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6229f8a9160ef739aa607c62c071c02
https://doi.org/10.1074/jbc.m702535200

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Evidence for Heterotypic Interaction between the Receptor Tyrosine Kinases TIE-1 and TIE-2

Autor: David P. Hughes, Cheryl L. Forder, Marie B. Marron, Nicholas P.J. Brindle, Edge Michael Derek

Publikováno v: Journal of Biological Chemistry. 275:39741-39746

The orphan receptor tyrosine kinase Tie-1 is expressed in endothelial cells and is essential for vascular development. Nothing is known about the signaling pathways utilized by this receptor. In this study we have used chimeric receptors composed of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7d46319d4026128fcc50bc092d8186
https://doi.org/10.1074/jbc.m007189200

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Nuclear and nucleolar localization of an African swine fever virus protein, I14L, that is similar to the herpes simplex virus-encoded virulence factor ICP34.5

Autor: Lynnette C. Goatley, Geoffrey L. Smith, Jef M. Hammond, James E. Miskin, Marie B. Marron, Susan C. Jacobs, Charles C. Abrams, Linda K. Dixon

Publikováno v: Journal of General Virology. 80:525-535

PCR analysis of the genomes of 18 different African swine fever virus (ASFV) isolates showed that the I14L open reading frame (ORF) was present as either a long form or short form in all of the isolates. Sequencing of the ORF from eight isolates conf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b684c742397288235ebd60f7e92e76c2
https://doi.org/10.1099/0022-1317-80-3-525

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Fimbrial adhesins: similarities and variations in structure and biogenesis

Autor: Stephen G. J. Smith, Jane Twohig, Marie B. Marron, Cyril J. Smyth

Publikováno v: FEMS Immunology & Medical Microbiology. 16:127-139

Fimbriae are wiry (2 to 4 nm diam.) or rod-shaped (6 to 8 nm diam.), fibre-like structures on the surfaces of bacteria which mediate attachment to host cells. Much has been learned in recent years about the biogenesis, structure and regulation of exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621ded2600c6a61b769253c6d64dbd2c
https://doi.org/10.1111/j.1574-695x.1996.tb00129.x

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Molecular analysis of the cso operon of enterotoxigenic Escherichia coli reveals that CsoA is the adhesin of CS1 fimbriae and that the accessory genes are interchangeable with those of the cfa operon

Autor: Marie B. Marron, Cyril J. Smyth

Publikováno v: Microbiology. 141:2849-2859

Summary: A deletion mutation in csoA, the gene encoding the structural subunit protein of CS1 fimbriae of enterotoxigenic Escherichia coli of serotype O6:K15:H16 or H -, was constructed in the subcloned CS1 genetic determinant. The mutation resulted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf980d9be4301bdb15d8143707ec6f1
https://doi.org/10.1099/13500872-141-11-2849

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Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2

Autor: Katja Kerkelä, Marie B. Marron, Nicholas P.J. Brindle, Gyun Min Lee, Niklas Ekman, Pipsa Saharinen, Gou Young Koh, Hellmut G. Augustin, Kari Alitalo

Publikováno v: The Journal of Cell Biology

The Tie1 receptor tyrosine kinase was isolated over a decade ago, but so far no ligand has been found to activate this receptor. Here, we have examined the potential of angiopoietins, ligands for the related Tie2 receptor, to mediate Tie1 activation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae3c3caeed712d3100c2a2459f37bf7
https://pubmed.ncbi.nlm.nih.gov/15851516

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The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2

Autor: Marie B. Marron, Nicholas P.J. Brindle, David P. Hughes

Publikováno v: Circulation research. 92(6)

Tie2 is a receptor tyrosine kinase expressed predominantly in endothelial cells and is essential for blood vessel formation and maintenance. The receptor has potent antiinflammatory effects on endothelial cells, suppressing vascular endothelial growt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3e978f16df14463d226438f3c67b7a
https://pubmed.ncbi.nlm.nih.gov/12676810

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Vascular endothelial growth factor modulates the Tie-2:Tie-1 receptor complex

Autor: Paul N. Morris, Marie B. Marron, Achilleas C. Tsiamis, Nicholas P.J. Brindle

Publikováno v: Microvascular research. 63(2)

The receptor tyrosine kinase Tie-1 is expressed predominantly in endothelial cells where it physically associates with the related receptor Tie-2. Positive signalling through Tie-2 is associated with microvessel stability and suppression of this sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ab7d26e70ec9b0877253f7cfabed84
https://pubmed.ncbi.nlm.nih.gov/11866538

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