Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marie A Iannone"'
Autor:
Christian Agosto‐Burgos, Eveline Y Wu, Marie A Iannone, Yichun Hu, Susan L Hogan, Candace D Henderson, Kristin B Kennedy, Lauren Blazek, Carolina A Herrera, Dominique Munson, Ronald J Falk, Dominic J Ciavatta, Meghan E Free
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 11, Pp n/a-n/a (2022)
Abstract Objectives T regulatory cells (Tregs) are a heterogeneous group of immunoregulatory cells that dampen self‐harming immune responses and prevent the development of autoimmune diseases. In anti‐neutrophil cytoplasmic autoantibody (ANCA) va
Externí odkaz:
https://doaj.org/article/680b925a8fee483e85a7f6dab3ad0451
Autor:
Marta Sanz, Ann Marie K. Weideman, Adam R. Ward, Matthew L. Clohosey, Susana Garcia-Recio, Sara R. Selitsky, Brendan T. Mann, Marie Anne Iannone, Chloe P. Whitworth, Alisha Chitrakar, Carolina Garrido, Jennifer Kirchherr, Alisha R. Coffey, Yi- Hsuan Tsai, Shahryar Samir, Yinyan Xu, Dennis Copertino, Alberto Bosque, Brad R. Jones, Joel S. Parker, Michael G. Hudgens, Nilu Goonetilleke, Natalia Soriano-Sarabia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Antiretroviral therapy (ART) is not curative due to the existence of cellular reservoirs of latent HIV-1 that persist during therapy. Current research efforts to cure HIV-1 infection include “shock and kill” strategies to disrupt latency using sm
Externí odkaz:
https://doaj.org/article/88374e57932242c08c418283c9d5a0d0
Autor:
Marie A. Iannone, Michelle R. Campbell, Douglas A. Bell, Suzanne N. Martos, Ma Wan, Gary S. Pittman
Publikováno v:
Cancer Research. 79:5057-5057
Tobacco smoke exposure is a risk factor for many human diseases and the global disease burden attributed to smoking remains substantial. In addition to DNA damage, smoking-induced epigenetic changes may contribute to etiology of complex smoking-assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0494e5b6bdbd5dfc28598bca999c7ff5
https://doi.org/10.1158/1538-7445.am2019-5057
https://doi.org/10.1158/1538-7445.am2019-5057
Autor:
Avinash Kollipara, Marie A. Iannone, Taylor Poston, De’Ashia E. Lee, Catherine O’Connell, Xiaojing Zheng, Sharon Hillier, Harold Wiesenfeld, Toni Darville
Publikováno v:
The Journal of Immunology. 200:166.16-166.16
Chlamydia trachomatis (CT) is the most frequently reported bacterial sexually transmitted infection in the U.S., with 1 in 20 sexually active young women being infected. Infections are easily curable with antibiotics, but reinfections are frequent an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439ac471878aca73b42927a95543977a
https://doi.org/10.4049/jimmunol.200.supp.166.16
https://doi.org/10.4049/jimmunol.200.supp.166.16
Autor:
Marie A. Iannone, Lisa M. Leesnitzer, Andrew N. Billin, Timothy M. Willson, Kenneth H. Pearce, Robert T. Nolte, William J. Hoekstra, Sumin M. Zhao, Richard G. Buckholz, Millard H. Lambert, Barry G. Shearer, Cobb Jeffrey Edmond, Ryan P. Trump
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3916-3920
PPARgamma-activating thiazolidinediones and carboxylic acids such as farglitazar exert their anti-diabetic effects in part in PPARgamma rich adipose. Both pro- and anti-adipogenic PPARgamma ligands promote glucose and lipid lowering in animal models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bc303ea054044b6e214de85d42ee90
https://doi.org/10.1016/j.bmcl.2007.04.111
https://doi.org/10.1016/j.bmcl.2007.04.111
Autor:
Dennis Heyer, Jean Baptiste E Blanc, Jean Shearin, Lisa A. Miller, Sue H. Kadwell, Timothy M. Willson, William J. Hoekstra, Xi Liang, Hari S. Patel, Marie A. Iannone, Kenneth H. Pearce, Catherine A. Simmons
Publikováno v:
Journal of Medicinal Chemistry. 48:2243-2247
Traditional approaches to discovery of selective estrogen receptor modulators (SERMs) have relied on ER binding and cell-based estrogen response element-driven assays to identify compounds that are osteoprotective but nonproliferative in breast and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e79f2a9a59cad162cc37106d6cbbe14
https://doi.org/10.1021/jm040154f
https://doi.org/10.1021/jm040154f
Publikováno v:
Drug Discovery Today. 9:741-751
There is currently a marketed drug for nearly every nuclear receptor for which the natural ligand has been identified. However, because of the complexity of signal transduction by this class of ligand-regulated transcription factors, few of these dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edd8d18bce0fd8f92ac6078bca2d489
https://doi.org/10.1016/s1359-6446(04)03201-5
https://doi.org/10.1016/s1359-6446(04)03201-5
Autor:
Marie A. Iannone, John G. Gray, Su Jun Deng, Kenneth H. Pearce, Dana E. Vanderwall, Thomas G. Consler, Catherine A. Simmons, Jean Shearin, Sue H. Kadwell, Daniel L. Svoboda
Publikováno v:
Molecular Endocrinology. 18:1064-1081
Numerous biochemical and structural studies have shown that the conformation of the estrogen receptor alpha (ERalpha) can be influenced by ligand binding. In turn, the conformational state of ERalpha affects the ability of the receptor to interact wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d2b59f816aa91dfe529419bc58c3d2
https://doi.org/10.1210/me.2003-0432
https://doi.org/10.1210/me.2003-0432
Autor:
Derek J. Parks, Thomas G. Consler, John G. Gray, Marie A. Iannone, Kenneth H. Pearce, Julie B. Stimmel
Publikováno v:
Cytometry. 44:326-337
Background We describe a novel microsphere-based system to identify and characterize multiplexed interactions of nuclear receptors with peptides that represent the LXXLL binding region of coactivator proteins. Methods In this system, individual micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5357180af1710a9e87c0fd9c0532b16
https://doi.org/10.1002/1097-0320(20010801)44:4<326::aid-cyto1124>3.0.co
https://doi.org/10.1002/1097-0320(20010801)44:4<326::aid-cyto1124>3.0.co
Autor:
Earnest Horne, Janet H. Parham, Christine R. Hoffman, Byron Ellis, Jane Bynum, Sue H. Kadwell, Kevin Blackburn, Wen-Ji Chen, Thomas G. Consler, Derril H. Willard, Marie A. Iannone, George Barrett
Publikováno v:
Protein Expression and Purification. 20:48-57
Receptor activator of NF-kappaB ligand (RANKL) is a type II transmembrane protein found on osteoblasts which functions as a major determinant of osteoclast differentiation and activation. RANKL mediates bone homeostasis through binding to the cognate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b033efb85a5d4fe85c3bb554e0b48ab
https://doi.org/10.1006/prep.2000.1278
https://doi.org/10.1006/prep.2000.1278