Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Marie Ranson"'
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102331- (2023)
Summary: Multi-cellular tumor spheroids (MCTS) have found widespread use in pre-clinical research. However, their complex three-dimensional structure makes immunofluorescent staining and imaging challenging. Here, we present a protocol for whole sphe
Externí odkaz:
https://doaj.org/article/dc622d3d4f924b9389dfddfe72dc74c4
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-23 (2022)
Abstract Cutaneous squamous cell carcinoma (cSCC) is a disease with globally rising incidence and poor prognosis for patients with advanced or metastatic disease. Epithelial-mesenchymal transition (EMT) is a driver of metastasis in many carcinomas, a
Externí odkaz:
https://doaj.org/article/9bc80b6e4d1a49ce841375bdf3ce6d41
Autor:
S. M. Zahid Hosen, Md. Nazim Uddin, Zhihong Xu, Benjamin J. Buckley, Chamini Perera, Tony C. Y. Pang, Alpha Raj Mekapogu, Mohammad Ali Moni, Faiyaz Notta, Steven Gallinger, Ron Pirola, Jeremy Wilson, Marie Ranson, David Goldstein, Minoti Apte
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrevious studies have revealed the role of dysregulated urokinase plasminogen activator (encoded by PLAU) expression and activity in several pathways associated with cancer progression. However, systematic investigation into the association
Externí odkaz:
https://doaj.org/article/389f362a1ff54af2905c59882ec6c0e9
Whole genome analysis reveals the genomic complexity in metastatic cutaneous squamous cell carcinoma
Autor:
Amarinder Singh Thind, Bruce Ashford, Dario Strbenac, Jenny Mitchell, Jenny Lee, Simon A. Mueller, Elahe Minaei, Jay R. Perry, Sydney Ch’ng, N. Gopalakrishna Iyer, Jonathan R. Clark, Ruta Gupta, Marie Ranson
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metastatic cutaneous squamous cell carcinoma (CSCC) is a highly morbid disease requiring radical surgery and adjuvant therapy, which is associated with a poor prognosis. Yet, compared to other advanced malignancies, relatively little is known of the
Externí odkaz:
https://doaj.org/article/1b54380ef9a04de4ae59a33d8f21f44b
Autor:
Timothy J. Eviston, Elahe Minaei, Simon A. Mueller, Navid Ahmadi, Bruce Ashford, Jonathan R. Clark, Nicholas West, Ping Zhang, Ruta Gupta, Marie Ranson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Perineural invasion (PNI) is frequently associated with aggressive clinical behaviour in head and neck cutaneous squamous cell carcinoma (HNcSCC) leading to local recurrence and treatment failure. This study evaluates the gene expression pro
Externí odkaz:
https://doaj.org/article/e93b3721fd0e471c9554e026e51d6ffd
Autor:
Robert Ariens, Cecilia Becattini, Markus Bender, Wolfgang Bergmeier, Elisabetta Castoldi, Katrien Devreese, Martin Ellis, David Gailani, Vera Ignjatovic, Paula D. James, Steven Kerrigan, Michele Lambert, Lai Heng Lee, Marcel Levi, Norma Maugeri, Joost Meijers, Juan Melero‐Martin, Alan D. Michelson, Federico Mingozzi, Keith Neeves, Heyu Ni, Anna‐Karin Olsson, Zoltán Prohászka, Marie Ranson, Nicoletta Riva, Yotis Senis, Cornelia H. vanOmmen, Douglas E. Vaughan, John Weisel
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 680-713 (2020)
Abstract The 2020 Congress of the International Society of Thrombosis and Haemostasis (ISTH) was held virtually July 12‐15, 2019, due to the coronavirus disease 2019 pandemic. The congress convenes annually to discuss clinical and basic topics in h
Externí odkaz:
https://doaj.org/article/27a44bdfe6e44090b3974f0f056fbfe5
Autor:
Elahe Minaei, Simon A. Mueller, Bruce Ashford, Amarinder Singh Thind, Jenny Mitchell, Jay R. Perry, Benjamin Genenger, Jonathan R. Clark, Ruta Gupta, Marie Ranson
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cutaneous squamous cell carcinoma (cSCC) of the head and neck region is the second most prevalent skin cancer, with metastases to regional lymph nodes occurring in 2%–5% of cases. To further our understanding of the molecular events characterizing
Externí odkaz:
https://doaj.org/article/3fab7cd4a9ee461d85584ffcb91394a7
Autor:
Jordan H. Cater, Noralyn B. Mañucat-Tan, Demi K. Georgiou, Guomao Zhao, Irina A. Buhimschi, Amy R. Wyatt, Marie Ranson
Publikováno v:
Cells, Vol 11, Iss 7, p 1152 (2022)
Plasminogen activator inhibitor type-2 (PAI-2), a member of the serpin family, is dramatically upregulated during pregnancy and in response to inflammation. Although PAI-2 exists in glycosylated and non-glycosylated forms in vivo, the majority of in
Externí odkaz:
https://doaj.org/article/34a7fcdb9212425a849bc06dbfa64f38
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 152 (2022)
Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and the poorest prognosis of all solid cancers. The urokinase plasminogen activation system (uPAS) is strongly implicated in the pathophysiology and clinical outc
Externí odkaz:
https://doaj.org/article/cb3a6ece27454a24b820ae7b7892de1f
Autor:
Daniel Brungs, Morteza Aghmesheh, Paul de Souza, Weng Ng, Wei Chua, Martin Carolan, Philip Clingan, Emma Healey, June Rose, Tameika Tubaro, Marie Ranson
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background/Aim Right sided colon cancer (RsCC) is proposed to be a distinct disease entity to left sided colon cancer (LsCC). We seek to confirm primary tumour location as an independent prognostic factor in locoregional colorectal cancer. M
Externí odkaz:
https://doaj.org/article/fffc72a41ca54a42a309af1336d753b5