Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Marie‐Nicole Theodoraki"'
Autor:
Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles they are involved in
Externí odkaz:
https://doaj.org/article/8febd94011434cd39ad0e08df9476fce
Autor:
Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage, Ralph Pries
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influenc
Externí odkaz:
https://doaj.org/article/00d90afcd16e4cecbcf18e983b6db96a
Autor:
Luisa Tengler, Moritz Tiedtke, Julia Schütz, Karen Bieback, Stefanie Uhlig, Marie-Nicole Theodoraki, Katja Nitschke, Thomas Stefan Worst, Elena Seiz, Claudia Scherl, Nicole Rotter, Sonja Ludwig
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Small extracellular vesicles from saliva (SEVs) have high potential as biomarkers in Head and Neck cancer (HNC). However, there is no common consensus on the ideal method for their isolation. This study compared different ultracentrifugation
Externí odkaz:
https://doaj.org/article/85dae743409c4b7ab7ae3db9fd7f4118
Autor:
Julius M. Vahl, Gabriele Nagel, Ayla Grages, Matthias Brand, Adrian vonWitzleben, Michael Sonntag, Marie‐Nicole Theodoraki, Jens Greve, Tsima Aboukors, Michael Denkinger, Dhayana Dallmeier, Christian Idel, Thomas K. Hoffmann, Simon Laban
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18826-18836 (2023)
Abstract Background Demographic development in rural and urban areas differs substantially. Demographics and access to specialized head and neck cancer centers may affect head and neck cancer patients' (HNCP) outcomes. Here, we compare epidemiologica
Externí odkaz:
https://doaj.org/article/a1465fdd240b4ed1b704c84412fc0dbc
Autor:
Luisa Tengler, Julia Schütz, Moritz Tiedtke, Jadwiga Jablonska, Marie-Nicole Theodoraki, Katja Nitschke, Christel Weiß, Elena Seiz, Annette Affolter, Frederic Jungbauer, Anne Lammert, Nicole Rotter, Sonja Ludwig
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-14 (2023)
Abstract Background In Head and neck cancer (HNC) angiogenesis is essential for tumor progression and metastasis. Small extracellular vesicles (sEVs) from HNC cell lines alter endothelial cell (EC) functions towards a pro-angiogenic phenotype. Howeve
Externí odkaz:
https://doaj.org/article/3c4c110c4b2d42b5ad0d78327d26b01c
Autor:
Linda Hofmann, Marie Waizenegger, Ralph Röth, Stefanie Schmitteckert, Daphne Engelhardt, Patrick J. Schuler, Simon Laban, Thomas K. Hoffmann, Cornelia Brunner, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundEpithelial to mesenchymal transition (EMT) is a key process in carcinogenesis of head and neck squamous cell carcinoma (HNSCC), contributing to tumor invasiveness, distant metastasis, and recurrence. Exosomes are known mediators and regulat
Externí odkaz:
https://doaj.org/article/da495342c7434169a99bd62712d7b29c
Autor:
Linda Hofmann, Tsima Abou Kors, Jasmin Ezić, Beate Niesler, Ralph Röth, Sonja Ludwig, Simon Laban, Patrick J. Schuler, Thomas K. Hoffmann, Cornelia Brunner, Valentin Medyany, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Head and neck squamous cell carcinomas (HNSCC) lack tumor-specific biomarkers. Exosomes from HNSCC patients carry immunomodulatory molecules, and correlate with clinical parameters. We compared miRNA profiles of plasma- and saliva-derived
Externí odkaz:
https://doaj.org/article/f4b07b257ef04856b71e8b242130684a
Autor:
Linda Hofmann, Valentin Medyany, Jasmin Ezić, Ramin Lotfi, Beate Niesler, Ralph Röth, Daphne Engelhardt, Simon Laban, Patrick J. Schuler, Thomas K. Hoffmann, Cornelia Brunner, Edwin K. Jackson, Marie-Nicole Theodoraki
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundExosomes contribute to immunosuppression in head and neck squamous cell carcinoma (HNSCC), a tumor entity which lacks specific tumor biomarkers. Plasma-derived exosomes from HNSCC patients correlate with clinical parameters and have potenti
Externí odkaz:
https://doaj.org/article/b081436aafca40e187dd665805d0efb6
Autor:
Annika C. Betzler, Sebastian Kieser, Katja Fiedler, Simon Laban, Marie-Nicole Theodoraki, Patrick J. Schuler, Thomas Wirth, Kerry Tedford, Klaus-Dieter Fischer, Thomas K. Hoffmann, Cornelia Brunner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Btk and Vav proteins are all components of the signalosome that builds upon B cell receptor (BCR) activation. However, the role of Vav proteins within the signalosome is quite complex and not yet fully understood. Until now, studies of these have foc
Externí odkaz:
https://doaj.org/article/0c03eaa83f2e4a4ab5ae78c0b4bca5dc
Autor:
Marie-Nicole Theodoraki, Akihiro Matsumoto, Inga Beccard, Thomas K. Hoffmann, Theresa L. Whiteside
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
The molecular cargo of tumor-cell-derived exosomes (TEX) mimics that of parental tumor cells. Thus, TEX could potentially serve as noninvasive biomarkers of cancer progression. However, separation of TEX from non-TEX in patients’ plasma requires tu
Externí odkaz:
https://doaj.org/article/2be8b8b2bfcb41dbb3bdba26f9a86a9d