Výsledky vyhledávání - "Marie‐Luce Le Bihan"

P73 expression in basal layers of head and neck squamous epithelium: a role in differentiation and carcinogenesis in concert with p53 and p63?

Autor: Marie‐Luce Le Bihan, Muriel Vayssade, Jean-Charles Ahomadegbe, Daniel Caput, Jacques Bosq, Laetitia Faridoni-Laurens, Mourad Kaghad, Jean Bénard, François Janot

Publikováno v: Oncogene. 20:5302-5312

P73, a p53-homologue gene, has been studied for its possible role in head and neck squamous epithelium (HNSE) differentiation and carcinogenesis. P73 RNA and protein were analysed in 50 biopsies, including well- and moderately-differentiated carcinom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17db91071b267e4cf5d06737cb350ce
https://doi.org/10.1038/sj.onc.1204687

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c-erbB-2 (HER-2/neu) gene amplification is a better indicator of poor prognosis than protein over-expression in operable breast-cancer patients

Autor: Jean Bénard, Marie-Christine Mathieu, Monique G. Lê, Guy Riou, Michel Barrois, Marie‐Luce Le Bihan, Jean-Charles Ahomadegbe

Publikováno v: International Journal of Cancer. 95:266-270

Our aim was to compare the prognostic value of c-erbB-2 gene amplification analyzed by Southern blot with that of protein (p185) over-expression measured by immunohistochemistry in 172 patients with operable breast cancer (BC). Amplification and p185

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eedc37658ccca3727bbbd8d9c66e8537
https://doi.org/10.1002/1097-0215(20010720)95:4<266::aid-ijc1045>3.0.co

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c-myc, p53 andbcl-2, apoptosis-related genes in infiltrating breast carcinomas: Evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients

Autor: Marie-Christine Mathieu, Sétha Douc-Rasy, Marc Spielmann, Howayda Adb El All, Monique G. Lê, Guy Riou, Marie‐Luce Le Bihan

Publikováno v: International Journal of Cancer. 84:562-567

Apoptosis is an important physiological process controlled by multiple genes, including c-myc, p53 and bcl-2, and its inhibition may lead to the development of human cancers. In this study, we analyzed expression of the c-myc gene using Northern blot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a89a44cd5c9cb832c8e66931af459bf
https://doi.org/10.1002/(sici)1097-0215(19991222)84:6<562::aid-ijc4>3.0.co

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