Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Marie‐Joelle Virolle"'
Autor:
Clara Lejeune, Sonia Abreu, Florence Guérard, Ahmed Askora, Michelle David, Pierre Chaminade, Bertrand Gakière, Marie‐Joelle Virolle
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Chassis strains, derived from Streptomyces coelicolor M145, deleted for one or more of its four main specialized metabolites biosynthetic pathways (CPK, CDA, RED and ACT), in various combinations, were constructed for the heterologous expres
Externí odkaz:
https://doaj.org/article/6b4c827c2127434b9b5912dc04f3ae18
Autor:
Yunwen Bi, Hao An, Zhewei Chi, Zhongheng Xu, Yuan Deng, Yuxian Ren, Rui Wang, Xinyi Lu, Jia Guo, Ren Hu, Marie-Joelle Virolle, Delin Xu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Streptomycetes are well-known antibiotic producers possessing in their genomes numerous silent biosynthetic pathways that might direct the biosynthesis of novel bio-active specialized metabolites. It is thus of great interest to find ways to enhance
Externí odkaz:
https://doaj.org/article/fc6ea7d0ab7244a6bfc9c74652eb17e3
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1560 (2024)
Since nitrogen limitation is known to be an important trigger of triacylglycerol (TAG) accumulation in most microorganisms, we first assessed the global lipid content of 21 strains derived from Streptomyces coelicolor M145 deleted for genes involved
Externí odkaz:
https://doaj.org/article/1877359a4a3f41a1829e41a2349a572d
Autor:
Cécile Apel, Marceau Levasseur, Clara Lejeune, Shaleen B. Korch, Florence Guérard, Michelle David, Ahmed Askora, Marc Litaudon, Fanny Roussi, Bertrand Gakière, John Chaput, Marie-Joelle Virolle
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms. However, such strategy has been rarely implemented in Streptomyces species whereas antibiotic product
Externí odkaz:
https://doaj.org/article/0e33224c9ec64e39b459f734fdfdc2f4
Autor:
Thierry Dulermo, Clara Lejeune, Ece Aybeke, Sonia Abreu, Jean Bleton, Michelle David, Ariane Deniset-Besseau, Pierre Chaminade, Annabelle Thibessard, Pierre Leblond, Marie-Joelle Virolle
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1470 (2023)
Streptomyces coelicolor M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in Streptomyces species. This strain abundantly produces the blue polyketide antibiotic, actinorhodin (ACT), and has a low lipid
Externí odkaz:
https://doaj.org/article/bbe276df92374be089ca44dbaebd4879
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
In most Streptomyces species, antibiotic production is triggered in phosphate limitation and repressed in phosphate proficiency. However, the model strain, Streptomyces coelicolor, escapes this general rule and produces actinorhoddin (ACT), a polyket
Externí odkaz:
https://doaj.org/article/2a92e6ba716941dea8385714cf41dac6
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Abstract Most currently used antibiotics originate from Streptomycetes and phosphate limitation is an important trigger of their biosynthesis. Understanding the molecular processes underpinning such regulation is of crucial importance to exploit the
Externí odkaz:
https://doaj.org/article/e2c0106a316a46dd93eab1c581e541f1
Autor:
Nicolas Seghezzi, Emmanuelle Darbon, Cécile Martel, Michelle David, Clara Lejeune, Catherine Esnault, Marie-Joelle Virolle
Publikováno v:
Antibiotics, Vol 11, Iss 9, p 1157 (2022)
In most Streptomyces species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low intracellular ATP content compared to growth in a condition of phosphate proficiency. This
Externí odkaz:
https://doaj.org/article/ecb9bac3b46c495c81cc2b0b672effed
Autor:
Clara Lejeune, Sonia Abreu, Pierre Chaminade, Thierry Dulermo, Michelle David, Sebastiaan Werten, Marie-Joelle Virolle
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
In this issue we demonstrated that the phospholipid content of Streptomyces lividans varies greatly with Pi availability being was much lower in Pi limitation than in Pi proficiency whereas that of Streptomyces coelicolor varied little with Pi availa
Externí odkaz:
https://doaj.org/article/226f727a9e0e4a2bbca484caca3b0762
Autor:
Jun Zhang, Qiting Liang, Zhongheng Xu, Miao Cui, Qizhong Zhang, Sonia Abreu, Michelle David, Clara Lejeune, Pierre Chaminade, Marie-Joelle Virolle, Delin Xu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
In condition of over-expression, SCO3201, a regulator of the TetR family was previously shown to strongly inhibit antibiotic production and morphological differentiation in Streptomyces coelicolor M145. In order to elucidate the molecular processes u
Externí odkaz:
https://doaj.org/article/4f5cd476515847ba8f91be1dcb078735