Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Marie‐France Penet"'
Autor:
Jesus Pacheco-Torres, Marie-France Penet, Yelena Mironchik, Balaji Krishnamachary, Zaver M. Bhujwalla
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Background Harnessing the power of the immune system by using immune checkpoint inhibitors has resulted in some of the most exciting advances in cancer treatment. The full potential of this approach has, however, not been fully realized for
Externí odkaz:
https://doaj.org/article/8db68ae8c2c048e9baa726a3d17de458
Autor:
Balaji Krishnamachary, Yelena Mironchik, Desmond Jacob, Eibhlin Goggins, Samata Kakkad, Francis Ofori, Louis Dore-Savard, Santosh Kumar Bharti, Flonne Wildes, Marie-France Penet, Margaret E Black, Zaver M Bhujwalla
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 679-688 (2020)
Hypoxia is frequently observed in human prostate cancer, and is associated with chemoresistance, radioresistance, metastasis, and castrate-resistance. Our purpose in these studies was to perform hypoxia theranostics by combining in vivo hypoxia imagi
Externí odkaz:
https://doaj.org/article/94007aec6209474f88e3fe69d26e9b91
Autor:
Santosh Kumar Bharti, Samata Kakkad, Pierre Danhier, Flonne Wildes, Marie-France Penet, Balaji Krishnamachary, Zaver M. Bhujwalla
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 2, Pp 239-246 (2019)
Metastatic dissemination continues to be a major cause of prostate cancer (PCa) mortality, creating a compelling need to understand factors that play a role in the metastatic cascade. Since hypoxia plays an important role in PCa aggressiveness, we ch
Externí odkaz:
https://doaj.org/article/805fae394954438d926c4b84f4035c50
Autor:
Jesus Pacheco-Torres, Marie-France Penet, Balaji Krishnamachary, Yelena Mironchik, Zhihang Chen, Zaver M. Bhujwalla
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
PurposeThe inhibition of immune checkpoints such as programmed cell death ligand-1 (PD-L1/CD274) with antibodies is providing novel opportunities to expose cancer cells to the immune system. Antibody based checkpoint blockade can, however, result in
Externí odkaz:
https://doaj.org/article/860445ef813442d6894c50ba732f14e3
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
In magnetic resonance metabolic imaging, signal from the water content is frequently used for normalization to derive quantitative or semi-quantitative values of metabolites in vivo or ex vivo tumors and tissues. Ex vivo high-resolution metabolic cha
Externí odkaz:
https://doaj.org/article/df3f5df137bf46df9a7f97537bcc475e
Autor:
Shanshan Tan, Zhihang Chen, Yelena Mironchik, Noriko Mori, Marie-France Penet, Ge Si, Balaji Krishnamachary, Zaver M. Bhujwalla
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1260 (2022)
The availability of nanoparticles (NPs) to deliver small interfering RNA (siRNA) has significantly expanded the specificity and range of ‘druggable’ targets for precision medicine in cancer. This is especially important for cancers such as triple
Externí odkaz:
https://doaj.org/article/2267f31d38b94590a7896d820d1eb352
Autor:
Sridhar Nimmagadda, Marie-France Penet
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Ovarian cancer is a leading cause of death from gynecological malignancies. Although the prognosis is quite favorable if detected at an early stage, the vast majority of cases are diagnosed at an advanced stage, when 5-year survival rates are only 30
Externí odkaz:
https://doaj.org/article/9998965dff89428e89c178959b2a8903
Autor:
Elizabeth W. Tucker, Supriya Pokkali, Zhi Zhang, Vincent P. DeMarco, Mariah Klunk, Elizabeth S. Smith, Alvaro A. Ordonez, Marie-France Penet, Zaver Bhujwalla, Sanjay K. Jain, Sujatha Kannan
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 12, Pp 1497-1506 (2016)
Central nervous system (CNS) tuberculosis (TB) is the most severe form of extra-pulmonary TB and disproportionately affects young children where the developing brain has a unique host response. New Zealand white rabbits were infected with Mycobacteri
Externí odkaz:
https://doaj.org/article/408503e117c54b19b3459ccd59d2c74f
Autor:
Marie-France Penet, Balaji Krishnamachary, Flonné B. Wildes, Yelena Mironchik, Chien-Fu Hung, TC Wu, Zaver M. Bhujwalla
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Epithelial ovarian cancer is the leading cause of death from gynecologic malignancy among women in developed countries. Epithelial ovarian cancer has a poor prognosis, due to the aggressive characteristics of the disease combined with the lack of eff
Externí odkaz:
https://doaj.org/article/bba5e769157f462daa2310587ccc3d65
Autor:
Marie-France Penet, Balaji Krishnamachary, Flonne Wildes, Yelena Mironchik, Delia Mezzanzanica, Franca Podo, Max DE REGGI, Bouchra Gharib, Zaver M Bhujwalla
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
Epithelial ovarian cancer remains the leading cause of death from gynecologic malignancy among women in developed countries. New therapeutic strategies evaluated with relevant preclinical models are urgently needed to improve survival rates. Here we
Externí odkaz:
https://doaj.org/article/ab2af60037b449669dedb5d614c9bc66