Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Marie‐Claude Potier"'
Autor:
Fanny Eysert, Paula-Fernanda Kinoshita, Julien Lagarde, Sandra Lacas-Gervais, Laura Xicota, Guillaume Dorothée, Michel Bottlaender, Frédéric Checler, Marie-Claude Potier, Marie Sarazin, Mounia Chami
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Mitochondrial dysfunctions are key features of Alzheimer’s disease (AD). The occurrence of these disturbances in the peripheral cells of AD patients and their potential correlation with disease progression are underinvestigated. We studied
Externí odkaz:
https://doaj.org/article/c121b4ea0df94f49962210d816a22ca2
Autor:
Bernhard T. Baune, Alessandra Minelli, Bernardo Carpiniello, Martina Contu, Jorge Domínguez Barragán, Chus Donlo, Ewa Ferensztajn-Rochowiak, Rosa Glaser, Britta Kelch, Paulina Kobelska, Grzegorz Kolasa, Dobrochna Kopeć, María Martínez de Lagrán Cabredo, Paolo Martini, Miguel-Angel Mayer, Valentina Menesello, Pasquale Paribello, Júlia Perera Bel, Giulia Perusi, Federica Pinna, Marco Pinna, Claudia Pisanu, Cesar Sierra, Inga Stonner, Viktor T. H. Wahner, Laura Xicota, Johannes C. S. Zang, Massimo Gennarelli, Mirko Manchia, Alessio Squassina, Marie-Claude Potier, Filip Rybakowski, Ferran Sanz, Mara Dierssen
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact. Pharmacotherapy represents the most common option among the first-line treatment choice; however, only about one third of patients res
Externí odkaz:
https://doaj.org/article/ebddcf97a00d4ab893aa34bffa18bb67
Autor:
Jean M. Delabar, Julien Lagarde, Marta Fructuoso, Ammara Mohammad, Michel Bottlaender, Eric Doran, Ira Lott, Isabelle Rivals, Frederic A. Schmitt, Elizabeth Head, Marie Sarazin, Marie-Claude Potier
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Early markers are needed for more effective prevention of Alzheimer’s disease. We previously showed that individuals with Alzheimer’s disease have decreased plasma DYRK1A levels compared to controls. We assessed DYRK1A in the plasma of c
Externí odkaz:
https://doaj.org/article/5d6a3bb197104b249fcbd404915e0cfc
Autor:
Laura Xicota, Julien Lagarde, Fanny Eysert, Benjamin Grenier-Boley, Isabelle Rivals, Alexandra Botté, Sylvie Forlani, Sophie Landron, Clément Gautier, Cecilia Gabriel, Michel Bottlaender, Jean-Charles Lambert, Mounia Chami, Marie Sarazin, Marie-Claude Potier
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Morphological alterations of the endosomal compartment have been widely described in post-mortem brains from Alzheimer’s disease (AD) patients and subjects with Down syndrome (DS) who are at high risk for AD. Immunostaining with antibodies
Externí odkaz:
https://doaj.org/article/b7f30749fb61429fb9afbbc24d6f5c53
Autor:
Susana Boluda, Karima Mokhtari, Bruno Mégarbane, Djillali Annane, Bertrand Mathon, Albert Cao, Clovis Adam, Alexandre Androuin, Franck Bielle, Guy Brochier, Frédéric Charlotte, Lydia Chougar, Khalid Hamid El Hachimi, Marc Eloit, Stéphane Haïk, Dominique Hervé, Amal Kasri, Valentin Leducq, Stéphane Lehéricy, Etienne Levavasseur, Christian Lobsiger, Geoffroy Lorin de La Grandmaison, Isabelle Malet, Isabelle Malissin, Stéphane Marot, Serge Marty, Philippe Pérot, Isabelle Plu, Annick Prigent, Lev Stimmer, Marie-Claude Potier, Anne-Geneviève Marcelin, Benoît Delatour, Charles Duyckaerts, Danielle Seilhean
Publikováno v:
Free Neuropathology, Vol 4 (2023)
In a neuropathological series of 20 COVID-19 cases, we analyzed six cases (three biopsies and three autopsies) with multiple foci predominantly affecting the white matter as shown by MRI. The cases presented with microhemorrhages evocative of small a
Externí odkaz:
https://doaj.org/article/05edf363d5d14e9389cc5d0000462bdb
Autor:
Arnaud Duchon, Maria del Mar Muñiz Moreno, Claire Chevalier, Valérie Nalesso, Philippe Andre, Marta Fructuoso-Castellar, Mary Mondino, Chrystelle Po, Vincent Noblet, Marie-Christine Birling, Marie-Claude Potier, Yann Herault
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/b9c8301d72d34dcea16c3c22b66ed21f
Autor:
Andrea Vergallo, Simone Lista, Yuhai Zhao, Pablo Lemercier, Stefan J. Teipel, Marie-Claude Potier, Marie-Odile Habert, Bruno Dubois, Walter J. Lukiw, Harald Hampel, for the INSIGHT-preAD study group, the Alzheimer Precision Medicine Initiative (APMI)
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract There is substantial experimental evidence for dysregulation of several microRNA (miRNA) expression levels in Alzheimer’s disease (AD). MiRNAs modulate critical brain intracellular signaling pathways and are associated with AD core pathoph
Externí odkaz:
https://doaj.org/article/45b05a077a4a4c348293ebbfacbdbd1f
Autor:
Alexandra Botté, Jeanne Lainé, Laura Xicota, Xavier Heiligenstein, Gaëlle Fontaine, Amal Kasri, Isabelle Rivals, Pollyanna Goh, Orestis Faklaris, Jack-Christophe Cossec, Etienne Morel, Anne-Sophie Rebillat, Dean Nizetic, Graça Raposo, Marie-Claude Potier
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-22 (2020)
Abstract Enlarged early endosomes have been visualized in Alzheimer’s disease (AD) and Down syndrome (DS) using conventional confocal microscopy at a resolution corresponding to endosomal size (hundreds of nm). In order to overtake the diffraction
Externí odkaz:
https://doaj.org/article/26fd67e10b014d1ab8afbad372ac26f6
Autor:
Kunie Ando, Marième Ndjim, Sabrina Turbant, Gaëlle Fontaine, Gustavo Pregoni, Luce Dauphinot, Zehra Yilmaz, Valérie Suain, Salwa Mansour, Michèle Authelet, Robert De Dekker, Karelle Leroy, Benoît Delatour, Brain Bank NeuroCEB Neuropathology Network, Charles Duyckaerts, Marie-Claude Potier, Jean-Pierre Brion
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Synaptojanin 1 (SYNJ1) is a brain-enriched lipid phosphatase critically involved in autophagosomal/endosomal trafficking, synaptic vesicle recycling and metabolism of phosphoinositides. Previous studies suggest that SYNJ1 polymorphisms have
Externí odkaz:
https://doaj.org/article/0a052a9fe57e48cdaf033a75854e03be
Autor:
Geoffrey Pires, Sacha McElligott, Shiron Drusinsky, Glenda Halliday, Marie-Claude Potier, Thomas Wisniewski, Eleanor Drummond
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract We recently identified Secernin-1 (SCRN1) as a novel amyloid plaque associated protein using localized proteomics. Immunohistochemistry studies confirmed that SCRN1 was present in plaque-associated dystrophic neurites and also revealed disti
Externí odkaz:
https://doaj.org/article/8c189191b8a54681aa029f35da706688