Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marie‐Claire D. Wasson"'
Autor:
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 91-112 (2024)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes. To investigate the mechanism of ALDH1A3‐med
Externí odkaz:
https://doaj.org/article/3963ad169532432cb23f181c5b3a6969
Autor:
Meghan E. McLean, Maya R. MacLean, Hannah F. Cahill, Raj Pranap Arun, Olivia L. Walker, Marie-Claire D. Wasson, Wasundara Fernando, Jaganathan Venkatesh, Paola Marcato
Publikováno v:
Cancers, Vol 15, Iss 2, p 492 (2023)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is one of 19 ALDH enzymes expressed in humans, and it is critical in the production of hormone receptor ligand retinoic acid (RA). We review the role of ALDH1A3 in normal physiology, its identification as a cancer
Externí odkaz:
https://doaj.org/article/42f3a6f9b55a4cf88f69d14bd0963dbf
Autor:
Brianne M. Cruickshank, Marie-Claire D. Wasson, Justin M. Brown, Wasundara Fernando, Jaganathan Venkatesh, Olivia L. Walker, Fiorella Morales-Quintanilla, Margaret L. Dahn, Dejan Vidovic, Cheryl A. Dean, Carter VanIderstine, Graham Dellaire, Paola Marcato
Publikováno v:
Cancers, Vol 13, Iss 11, p 2644 (2021)
Triple-negative breast cancers (TNBCs) are aggressive, lack targeted therapies and are enriched in cancer stem cells (CSCs). Novel therapies which target CSCs within these tumors would likely lead to improved outcomes for TNBC patients. Long non-codi
Externí odkaz:
https://doaj.org/article/efc28cf05d8145abbe04f8a5ab7aaedc
Publikováno v:
Cancers, Vol 13, Iss 2, p 296 (2021)
The COVID-19 pandemic has caused the need for prioritization strategies for breast cancer treatment, where patients with aggressive disease, such as triple-negative breast cancer (TNBC) are a high priority for clinical intervention. In this review, w
Externí odkaz:
https://doaj.org/article/b8eb6ae2b664499aaa536643c5c632cc
Autor:
Margaret L. Dahn, Hayley R. Walsh, Cheryl A. Dean, Michael A. Giacomantonio, Wasundara Fernando, J Patrick Murphy, Olivia L. Walker, Marie-Claire D. Wasson, Shashi Gujar, Devanand M. Pinto, Paola Marcato
Publikováno v:
Metabolomics
Introduction Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC) marker and in breast cancer it is associated with triple-negative/basal-like subtypes and aggressive disease. Studies on the mechanisms of ALDH1A3 in cancer have primarily
Autor:
Maxwell P. Bui-Marinos, Marie-Claire D. Wasson, Barbara A. Katzenback, Brandon E. E. Morningstar, Lauren A. Todd
Publikováno v:
Developmental and comparative immunology. 124
Frog virus 3 (FV3) causes mortality in a range of amphibian species. Despite the importance of the skin epithelium as a first line of defence against FV3, the interaction between amphibian skin epithelial cells and FV3 remains largely uncharacterized
Autor:
Marie-Claire D Wasson, Jaganathan Venkatesh, Paola Marcato, Justin M Brown, Wasundara Fernando
Publikováno v:
Data in Brief
Data in Brief, Vol 37, Iss, Pp 107241-(2021)
Data in Brief, Vol 37, Iss, Pp 107241-(2021)
Long non-coding RNA (lncRNA)/microRNA (miRNA)/messenger RNA (mRNA) interactions regulate oncogenesis and tumour suppression in breast cancer. Oncogenic lncRNA/miRNA/mRNA axes may offer novel therapeutic targets; therefore, identifying such axes is a
Autor:
Olivia L Walker, Justin M Brown, Cheryl A. Dean, Wasundara Fernando, Paola Marcato, Graham Dellaire, Brianne M. Cruickshank, Margaret L. Dahn, Marie-Claire D Wasson, Dejan Vidovic, Carter VanIderstine, Fiorella Morales-Quintanilla, Jaganathan Venkatesh
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Triple-negative breast cancers (TNBCs) are aggressive, lack targeted therapies and are enriched in cancer stem cells (CSCs). Novel therapies which target CSCs within these tumors would likely lead to improved outcomes for TNBC patients. Long non-codi
Autor:
Marie-Claire D Wasson, Paola Marcato, Wasundara Fernando, Jaganathan Venkatesh, Justin M Brown
Publikováno v:
Cancer letters. 509
Therapeutic effectiveness in breast cancer can be limited by the underlying mechanisms of pathogenesis, including epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) and drug resistance. Long non-coding RNAs (lncRNAs) and microRNAs (miR
Publikováno v:
Cells
Cells, Vol 9, Iss 3, p 763 (2020)
Cells, Vol 9, Iss 3, p 763 (2020)
Treatment decisions for breast cancer are based on staging and hormone receptor expression and include chemotherapies and endocrine therapy. While effective in many cases, some breast cancers are resistant to therapy, metastasize and recur, leading t