Výsledky vyhledávání - "Marie, Zadinova"

Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues

Autor: Olga Janoušková, Richard Hoogenboom, Marie Zadinova, Maarten Vergaelen, Martin Hruby, Bart Verbraeken, Ondrej Sedlacek, Jana Mattova, Bryn D. Monnery, Anita Höcherl, Jan Kučka, Jiri Panek

Publikováno v: Biomaterials. 146

We designed and synthesized a new delivery system for the anticancer drug doxorubicin based on a biocompatible hydrophilic poly(2-ethyl-2-oxazoline) (PEtOx) carrier with linear architecture and narrow molar mass distribution. The drug is connected to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989fefdf71137aab3f568395fee10df5
https://pubmed.ncbi.nlm.nih.gov/28892751

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Multistage-targeted pH-responsive polymer conjugate of Auger electron emitter: Optimized design and in vivo activity

Autor: Pavla Pouckova, Jana Mattova, Marie Zadinova, Martin Studenovsky, Martin Hruby, Ondrej Sedlacek, Martin Parizek, Jan Kučka

Publikováno v: European Journal of Pharmaceutical Sciences. 63:216-225

Auger electrons-emitting radioisotopes (such as iodine-125) are a potentially effective cancer treatment. They are extremely biologically effective, but only within a short range (nanometers). Their use as an effective cancer therapy requires that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9675cb037d74e0ed9eb1f5fac4bd5108
https://doi.org/10.1016/j.ejps.2014.07.012

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Optimum modality for photodynamic therapy of tumors: gels containing liposomes with hydrophobic photosensitizers

Autor: Milos Nekvasil, Petr Ježek, Marie Zadinova, Ludmila Tahotná, Markéta Žáčková, Pavla Pouckova

Publikováno v: Drug Development Research. 68:235-252

Photodynamic therapy (PDT) has entered an era of clinical acceptance; however, for its wider use, including drug formulations for topical applications, it must have a rapid effect and be free of skin-photosensitization effects. Preclinical studies of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8963ecc5f22574723b84c823329a148f
https://doi.org/10.1002/ddr.20184

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Dual role of host Par2 in a murine model of spontaneous metastatic B16 melanoma

Autor: Tomas, Olejar, David, Vetvicka, Marie, Zadinova, Pavla, Pouckova, Jaromir, Kukal, Petr, Jezek, Radoslav, Matej

Publikováno v: Anticancer research. 34(7)

We investigated differences of metastatic spread of normal proteinase-activated receptor-2 (Par2+/+) melanoma B16 in Par2-/- (knock-out) animals compared to C57Bl6 mice.Nine knock-out mice B6.Cg-F2rl1tm1Mslb/J (Par2-/-) and nine C57Bl6/J controls wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f71621f3cf56859f0b761488bd49a20b
https://pubmed.ncbi.nlm.nih.gov/24982362

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Novel topical photodynamic therapy of prostate carcinoma using hydroxy-aluminum phthalocyanine entrapped in liposomes

Autor: Karol, Sutoris, Jan, Rakusan, Marie, Karaskova, Jana, Mattova, Jiri, Benes, Milos, Nekvasil, Petr, Jezek, Marie, Zadinova, Pavla, Pouckova, David, Vetvicka

Publikováno v: Anticancer research. 33(4)

Clinically-approved anticancer photodynamic therapy (PDT) is now extensively studied for various cancer diagnoses. We focused on the treatment efficacy of topical administration of hydroxy-aluminum phthalocyanine (AlOH-PC) entrapped in liposomes agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e3ca49617ecae9b1b6b350ecc7f6539
https://pubmed.ncbi.nlm.nih.gov/23564798

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