Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Marie, Sjöberg"'
Autor:
Bockholt, Kajsa, Marie, Sjöberg
Syftet med denna studie har varit att undersöka erfarna slöjdlärares upplevelser om hur upphävandet av slöjdvalet på högstadiet har påverkat slöjdundervisningen. Studien genomfördes med den kvalitativa intervjun som metod och utgick ifrån
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-221515
Autor:
Ornella Bimai, Ipsita Banerjee, Inna Rozman Grinberg, Ping Huang, Lucas Hultgren, Simon Ekström, Daniel Lundin, Britt-Marie Sjöberg, Derek T Logan
Publikováno v:
eLife, Vol 12 (2024)
A small, nucleotide-binding domain, the ATP-cone, is found at the N-terminus of most ribonucleotide reductase (RNR) catalytic subunits. By binding adenosine triphosphate (ATP) or deoxyadenosine triphosphate (dATP) it regulates the enzyme activity of
Externí odkaz:
https://doaj.org/article/58c8ed64ca754d1ea6c8072d269703e7
Autor:
Inna Rozman Grinberg, Markel Martínez-Carranza, Ornella Bimai, Ghada Nouaïria, Saher Shahid, Daniel Lundin, Derek T. Logan, Britt-Marie Sjöberg, Pål Stenmark
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Ribonucleotide reductase (RNR) is an essential enzyme that catalyzes the synthesis of DNA building blocks. Here, the authors present the cryo-EM structure and mechanism of action of NrdR, the RNR-specific repressor, that controls transcription of RNR
Externí odkaz:
https://doaj.org/article/c11cf65babe14228a3e8ad1e379ec405
Autor:
Susanne Fransson, Angela Martinez-Monleon, Mathias Johansson, Rose-Marie Sjöberg, Caroline Björklund, Gustaf Ljungman, Torben Ek, Per Kogner, Tommy Martinsson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Neuroblastoma is the most common and deadly childhood tumor. Relapsed or refractory neuroblastoma has a very poor prognosis despite recent treatment advances. To investigate genomic alterations associated with relapse and therapy resistance,
Externí odkaz:
https://doaj.org/article/040e279adcf3445389b188aed659660d
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The essential enzyme ribonucleotide reductase (RNR) is highly regulated both at the level of overall activity and substrate specificity. Studies of class I, aerobic RNRs have shown that overall activity is downregulated by the binding of dATP to a sm
Externí odkaz:
https://doaj.org/article/de0fb2415a274c318ff68f735ff3b807
Autor:
Joachim Tetteh Siaw, Niloufar Javanmardi, Jimmy Van den Eynden, Dan Emil Lind, Susanne Fransson, Angela Martinez-Monleon, Anna Djos, Rose-Marie Sjöberg, Malin Östensson, Helena Carén, Gunhild Trøen, Klaus Beiske, Ana P. Berbegall, Rosa Noguera, Wei-Yun Lai, Per Kogner, Ruth H. Palmer, Bengt Hallberg, Tommy Martinsson
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108171- (2020)
Summary: High-risk neuroblastomas typically display an undifferentiated or poorly differentiated morphology. It is therefore vital to understand molecular mechanisms that block the differentiation process. We identify an important role for oncogenic
Externí odkaz:
https://doaj.org/article/01191b05e5974287a9be5d2989de4d0a
Autor:
Daniel Rehling, Emma Rose Scaletti, Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin, Anders Hofer, Britt-Marie Sjöberg, Pål Stenmark
Publikováno v:
Biochemistry. 61:92-106
Ribonucleotide reductase (RNR) is an essential enzyme with a complex mechanism of allosteric regulation found in nearly all living organisms. Class I RNRs are composed of two proteins, a large α-subunit (R1) and a smaller β-subunit (R2) that exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61c6d39c35d422422390dbfa20f27e1
https://doi.org/10.1021/acs.biochem.1c00503
https://doi.org/10.1021/acs.biochem.1c00503
Autor:
Inna Rozman Grinberg, Daniel Lundin, Mahmudul Hasan, Mikael Crona, Venkateswara Rao Jonna, Christoph Loderer, Margareta Sahlin, Natalia Markova, Ilya Borovok, Gustav Berggren, Anders Hofer, Derek T Logan, Britt-Marie Sjöberg
Publikováno v:
eLife, Vol 7 (2018)
Ribonucleotide reductases (RNRs) are key enzymes in DNA metabolism, with allosteric mechanisms controlling substrate specificity and overall activity. In RNRs, the activity master-switch, the ATP-cone, has been found exclusively in the catalytic subu
Externí odkaz:
https://doaj.org/article/b748293d383c40c1839ef9c37f256aa8
Publikováno v:
Life, Vol 5, Iss 1, Pp 604-636 (2015)
Ribonucleotide reduction is the only pathway for de novo synthesis of deoxyribonucleotides in extant organisms. This chemically demanding reaction, which proceeds via a carbon-centered free radical, is catalyzed by ribonucleotide reductase (RNR). The
Externí odkaz:
https://doaj.org/article/a0331eec93d94a169252f5d16c891f39
Autor:
Gustaf Ljungman, Per Kogner, Tommy Martinsson, Angela Martinez-Monleon, Caroline Björklund, Torben Ek, Mathias Johansson, Rose-Marie Sjöberg, Susanne Fransson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Neuroblastoma is the most common and deadly childhood tumor. Relapsed or refractory neuroblastoma has a very poor prognosis despite recent treatment advances. To investigate genomic alterations associated with relapse and therapy resistance, whole-ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c14a0094aa5e197dd67701aeed07c2c
https://doaj.org/article/040e279adcf3445389b188aed659660d
https://doaj.org/article/040e279adcf3445389b188aed659660d