Zobrazeno 1 - 10 of 134 pro vyhledávání: '"Marie, Maynadier"'
1
Akademický článek
Therapeutic antibody engineering for efficient targeted degradation of membrane proteins in lysosomes
Autor: Corentin Gauthier, Morgane Daurat, Lamiaa Mohamed Ahmed Ali, Khaled El Cheikh, Iris El Bahlagui, Camille Taliercio, Elodie Morère, Magali Gary-Bobo, Alain Morère, Marcel Garcia, Marie Maynadier, Ilaria Basile
Publikováno v: Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116707- (2024)
Targeted degradation of pathological proteins is a promising approach to enhance the effectiveness of therapeutic monoclonal antibodies (mAbs) in cancer therapy. In this study, we demonstrate that this objective can be efficiently achieved by the gra
Externí odkaz: https://doaj.org/article/56cca71628804d40a91775fbd57697fe
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2
Akademický článek
Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins
Autor: Morgane Daurat, Corentin Gauthier, Khaled El Cheikh, Lamiaa M. A. Ali, Elodie Morère, Nadir Bettache, Magali Gary-Bobo, Alain Morère, Marcel Garcia, Marie Maynadier, Ilaria Basile
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Inducing the degradation of pathological soluble antigens could be the key to greatly enhancing the efficacy of therapeutic monoclonal antibodies (mAbs), extensively used in the treatment of autoimmune and inflammatory disorders or cancer. Lysosomal
Externí odkaz: https://doaj.org/article/e49cd1cf5124458e964f2415b5fa61ec
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4
Akademický článek
Efficient Photodynamic Therapy of Prostate Cancer Cells through an Improved Targeting of the Cation-Independent Mannose 6-Phosphate Receptor
Autor: Elise Bouffard, Chiara Mauriello Jimenez, Khaled El Cheikh, Marie Maynadier, Ilaria Basile, Laurence Raehm, Christophe Nguyen, Magali Gary-Bobo, Marcel Garcia, Jean-Olivier Durand, Alain Morère
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 11, p 2809 (2019)
The aim of the present work is the development of highly efficient targeting molecules to specifically address mesoporous silica nanoparticles (MSNs) designed for the photodynamic therapy (PDT) of prostate cancer. We chose the strategy to develop a n
Externí odkaz: https://doaj.org/article/60303d404a5349ec9239a8e519956f19
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5
Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications
Autor: Olivier Maury, Sophie Brasselet, Raphaël Tripier, Jean-Christophe Mulatier, Nadir Bettache, Marie Maynadier, Magali Gary-Bobo, Maryline Beyler, Christophe Nguyen, Alexei Grichine, Nadège Hamon, Chantal Andraud, Alain Duperray, Amandine Roux
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
International audience; In addition to the already described ligand L4a, two pyclen-based lanthanide chelators, L4b and L4c, bearing two specific picolinate two-photon antennas (tailor-made for each targeted metal) and one acetate arm arranged in a d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de392b14cfe2e36b60c2c6794ade903d
https://doi.org/10.1021/jacs.0c03496
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6
Akademický článek
Biosafety of Mesoporous Silica Nanoparticles
Autor: Estelle Rascol, Cédric Pisani, Christophe Dorandeu, Jeff L. Nyalosaso, Clarence Charnay, Morgane Daurat, Afitz Da Silva, Jean-Marie Devoisselle, Jean-Charles Gaillard, Jean Armengaud, Odette Prat, Marie Maynadier, Magali Gary-Bobo, Marcel Garcia, Joël Chopineau, Yannick Guari
Publikováno v: Biomimetics, Vol 3, Iss 3, p 22 (2018)
Careful analysis of any new nanomedicine device or disposal should be undertaken to comprehensively characterize the new product before application, so that any unintended side effect is minimized. Because of the increasing number of nanotechnology-b
Externí odkaz: https://doaj.org/article/2f811c8c9cf244099d374f56799ef46a
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7
A 'Multi‐Heavy‐Atom' Approach toward Biphotonic Photosensitizers with Improved Singlet‐Oxygen Generation Properties
Autor: Olivier Maury, Tangui Le Bahers, Raphaël Tripier, Margaux Galland, Chantal Andraud, N. Lascoux, Alain Duperray, Akos Banyasz, Yannick Guyot, Cyrille Monnereau, Alexei Grichine, Marie Maynadier, Christophe Nguyen, Magali Gary-Bobo
Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2019, 25 (38), pp.9026-9034. ⟨10.1002/chem.201901047⟩
Chemistry-A European Journal, 2019, 25 (38), pp.9026-9034. ⟨10.1002/chem.201901047⟩
Dr. Y. Bretonnière and Dr. M. Rémond for their help in the preparation of Pluronic nanoparticles.IAB platform was co-funded thanks to grants of ‘‘Association pour la Recherche sur le Cancer’’ (ARC, Villejuif, France),‘‘Ligue Contre le C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac397020509f6f7fbc24ebfb33c1aa3
https://doi.org/10.1002/chem.201901047
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9
Fluorescent periodic mesoporous organosilica nanoparticles dual-functionalized via click chemistry for two-photon photodynamic therapy in cells
Autor: Marie Maynadier, Laurence Raehm, Jean-Olivier Durand, Xavier Cattoën, Marcel Garcia, Maxime Klausen, Sébastien Picard, Dina Aggad, Guillaume Clermont, Chiara Mauriello Jimenez, Mireille Blanchard-Desce, Jonas G. Croissant, Emilie Genin, Michel Wong Chi Man, Magali Gary-Bobo, Olivier Mongin
Publikováno v: Journal of Materials Chemistry B: Materials for Biology and Medicine
Journal of Materials Chemistry B: Materials for Biology and Medicine, 2016, 4 (33), pp.5567--5574. ⟨10.1039/c6tb00638h⟩
Journal of Materials Chemistry B: Materials for Biology and Medicine, Royal Society of Chemistry, 2016, 4 (33), pp.5567--5574. ⟨10.1039/c6tb00638h⟩
The synthesis of ethenylene-based periodic mesoporous organosilica nanoparticles for two-photon imaging and photodynamic therapy of breast cancer cells is described. A dedicated two-photon absorbing fluorophore possessing four triethoxysilyl groups a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696dad4be7ca38ccaa5ea9b30f05cad2
https://pubmed.ncbi.nlm.nih.gov/32263353
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10
Influence of the synthetic method on the properties of two-photon-sensitive mesoporous silica nanoparticles
Autor: Marie Maynadier, Laurence Raehm, Clarence Charnay, Michel Wong Chi Man, Vanja Stojanovic, Xavier Cattoën, Magali Gary-Bobo, Olivier Mongin, Jonas G. Croissant, Jean-Olivier Durand, Mireille Blanchard-Desce, Marcel Garcia, Vincent Hugues
Publikováno v: Journal of Materials Chemistry B: Materials for Biology and Medicine
Journal of Materials Chemistry B: Materials for Biology and Medicine, 2015, 3 (26), pp.5182--5188. ⟨10.1039/c5tb00787a⟩
Journal of Materials Chemistry B: Materials for Biology and Medicine, Royal Society of Chemistry, 2015, 3 (26), pp.5182--5188. ⟨10.1039/c5tb00787a⟩
International audience; Herein we report the modulation of the properties of mesoporous silica nanoparticles (NPs) via various synthetic approaches. Three types of elaborations were compared, one in aqueous media at 25 °C, and the other two at 80 °
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e72428bf8317b3134514265295f9f8
https://pubmed.ncbi.nlm.nih.gov/32262593
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