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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

Autor: Matias, Maria I., Yong, Carmen S., Foroushani, Amir, Goldsmith, Chloe, Mongellaz, Cédric, Sezgin, Erdinc, Levental, Kandice R., Talebi, Ali, Perrault, Julie, Rivière, Anais, Dehairs, Jonas, Delos, Océane, Bertand-Michel, Justine, Portais, Jean-Charles, Wong, Madeline, Marie, Julien C., Kelekar, Ameeta, Kinet, Sandrina, Zimmermann, Valérie S., Levental, Ilya, Yvan-Charvet, Laurent, Swinnen, Johannes V., Muljo, Stefan A., Hernandez-Vargas, Hector, Tardito, Saverio, Taylor, Naomi, Dardalhon, Valérie

Publikováno v: In Cell Reports 2 November 2021 37(5)

MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype

Autor: Plantamura, Emilie, Dzutsev, Amiran, Chamaillard, Mathias, Djebali, Sophia, Moudombi, Lyvia, Boucinha, Lilia, Grau, Morgan, Macari, Claire, Bauché, David, Dumitrescu, Oana, Rasigade, Jean-Philippe, Lippens, Saskia, Plateroti, Michelina, Kress, Elsa, Cesaro, Annabelle, Bondu, Clovis, Rothermel, Ulrike, Heikenwälder, Mathias, Lina, Gerard, Bentaher-Belaaouaj, Azzak, Marie, Julien C., Caux, Christophe, Trinchieri, Giorgio, Marvel, Jacqueline, Michallet, Marie-Cecile

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2018 Oct 01. 115(41), 10404-10409.

Externí odkaz: https://www.jstor.org/stable/26532191

Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation

Autor: Lainé, Alexandra, Labiad, Ossama, Hernandez-Vargas, Hector, This, Sébastien, Sanlaville, Amélien, Léon, Sophie, Dalle, Stéphane, Sheppard, Dean, Travis, Mark A., Paidassi, Helena, Marie, Julien C.

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, 2021, 12, pp.6228. ⟨10.1038/s41467-021-26352-2⟩

Presence of TGFβ in the tumor microenvironment is one of the most relevant cancer immune-escape mechanisms. TGFβ is secreted in an inactive form, and its activation within the tumor may depend on different cell types and mechanisms than its product

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7674595bee38c19e699cedf83e4a394f
https://doaj.org/article/0099bf33b303405fa97900689fb2a35e

Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control

Autor: Havenar-Daughton, Colin, Li, Shamin, Benlagha, Kamel, Marie, Julien C.

Publikováno v: In Blood 12 April 2012 119(15):3486-3494