Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maricela Prado"'
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 758-767 (2019)
Abstract As common chemotherapeutic agents are associated with an increased risk of acute and chronic cardiovascular complications, a new clinical discipline, cardio‐oncology, has recently emerged. At the same time, the development of preclinical h
Externí odkaz:
https://doaj.org/article/f168dfe26de044b5b7b35e7ea8be2d8b
Autor:
Prashila L Amatya, Mark Mercola, Jennifer Arthur Ataam, Michelle Vu, Alexandra A Gavidia, Renee G.C. Maas, Wouter P. te Rijdt, Ting-Hsuan Wu, Maricela Prado, Albert J. H. Suurmeijer, Ioannis Karakikes, Logan Dunkenberger, Joost P.G. Sluijter, Isaac Perea-Gil, Nirmal Vadgama, Aryan Vink, Yuan Zhang, Jiayi Pei, Karim Sallam, Magdalena Harakalova, Dries A.M. Feyen, Folkert W. Asselbergs
Publikováno v:
Circulation, 144(5), 382-392. Lippincott Williams and Wilkins
Circulation, 144(5), 382-392. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Circulation, 144(5), 382-392. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Background: Phospholamban (PLN) is a critical regulator of calcium cycling and contractility in the heart. The loss of arginine at position 14 in PLN (R14del) is associated with dilated cardiomyopathy with a high prevalence of ventricular arrhythmias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b598da7adccee3845068562c6754cc13
https://research.rug.nl/en/publications/53ce900f-a727-4f43-856f-e44f401904b9
https://research.rug.nl/en/publications/53ce900f-a727-4f43-856f-e44f401904b9
Autor:
Ricardo Serrano, Dries Feyen, Arne A Bruyneel, Anna Hnatiuk Hnatiuk, Michelle Vu, Prashila Amatya, Isaac Perea Gil, Maricela Prado, Timon Seeger, Joseph C Wu, Ioannis Karakikes, Mark Mercola
Publikováno v:
Circulation Research. 131
Introduction: Drug-induced arrhythmias are a common cause for drug attrition during development and for restricted use or withdrawal from the market. Cell based assays to assess arrhythmia risk typically rely on the quantification of waveform feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::015a8fa1dd0afdc166db5f23e6118990
https://doi.org/10.1161/res.131.suppl_1.p2109
https://doi.org/10.1161/res.131.suppl_1.p2109
Autor:
Ricardo Serrano, Dries A.M. Feyen, Arne A.N. Bruyneel, Anna P. Hnatiuk, Michelle M. Vu, Prashila L. Amatya, Isaac Perea-Gil, Maricela Prado, Timon Seeger, Joseph C. Wu, Ioannis Karakikes, Mark Mercola
Publikováno v:
Cell stem cell.
Drug safety initiatives have endorsed human iPSC-derived cardiomyocytes (hiPSC-CMs) as an in vitro model for predicting drug-induced cardiac arrhythmia. However, the extent to which human-defined features of in vitro arrhythmia predict actual clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae84d73d4afd7d7ea9cd77d90b5c126
https://pubmed.ncbi.nlm.nih.gov/36563695
https://pubmed.ncbi.nlm.nih.gov/36563695
Autor:
Timon Seeger, Alex C.Y. Chang, Isaac Perea-Gil, Mohamed Ameen, Thomas J. LaRocca, Brigham H. Mecham, Evgenios Neofytou, Gaurav Pandey, Ioannis Karakikes, Maricela Prado, Joseph C. Wu
Publikováno v:
Circ Heart Fail
Background: MicroRNAs are small, noncoding RNAs that play a key role in gene expression. Accumulating evidence suggests that aberrant microRNA expression contributes to the heart failure (HF) phenotype; however, the underlying molecular mechanisms ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b7e89082fd3b680fa967b51dc7cd7e
https://doi.org/10.1161/circheartfailure.119.006298
https://doi.org/10.1161/circheartfailure.119.006298
Autor:
Yonggang Liu, Oscar J. Abilez, Evgenios Neofytou, Joseph C. Wu, Sadhana Gaddam, Thomas B. Hildebrandt, Xulei Qin, Huaxiao Yang, Howard Y. Chang, Maricela Prado, Maxwell R. Mumbach, Mohamed Ameen, Mingxia Gu, Hongchao Guo, Ning Ma, Lei Tian, Ioannis Karakikes, Kitchener D. Wilson, Nathan J. Cunningham, Sebastian Diecke
Publikováno v:
Developmental cell. 54(6)
Transposable elements (TEs) comprise nearly half of the human genome and are often transcribed or exhibit cis-regulatory properties with unknown function in specific processes such as heart development. In the case of endogenous retroviruses (ERVs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4c4df64cbc42f8b0532311a0b17deb
https://pubmed.ncbi.nlm.nih.gov/32991832
https://pubmed.ncbi.nlm.nih.gov/32991832