Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marica Vaapil"'
Autor:
Marica Vaapil, Karolina Helczynska, René Villadsen, Ole W Petersen, Elisabet Johansson, Siv Beckman, Christer Larsson, Sven Påhlman, Annika Jögi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46543 (2012)
INTRODUCTION: Solid tumors are less oxygenated than their tissue of origin. Low intra-tumor oxygen levels are associated with worse outcome, increased metastatic potential and immature phenotype in breast cancer. We have reported that tumor hypoxia c
Externí odkaz:
https://doaj.org/article/6b9e2f2b0a514e9a992ebed80ac7bd73
Autor:
Olivier De Wever, Irina Lambertz, Frank Speleman, Shana Claeys, Daniel Bexell, Christophe Van Neste, Bram De Wilde, Kaat Durinck, Bengt Hallberg, Geertrui Denecker, Matthias Fischer, Genevieve Laureys, Candy Kumps, Ganesh Umapathy, Christoph Bartenhagen, Johannes H. Schulte, Marica Vaapil, Katleen De Preter, Wouter Van Loocke, Liselot Mus
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an urgent need for novel targeted therapeutic approaches. Detailed molecular characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a18d11f0232bbd2369b1c329772c60
https://doi.org/10.1038/s41598-019-57076-5
https://doi.org/10.1038/s41598-019-57076-5
Publikováno v:
Meng, Peng; Vaapil, Marica; Tagmount, Abderrahmane; Loguinov, Alex; Vulpe, Chris; & Yaswen, Paul. (2019). Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures.. Breast cancer research and treatment. doi: 10.1007/s10549-019-05229-5. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/9p95k6vz
Breast cancer research and treatment, vol 176, iss 1
Breast cancer research and treatment, vol 176, iss 1
PURPOSE:Understanding how differentiation, microenvironment, and hormonal milieu influence human breast cell susceptibility to malignant transformation will require the use of physiologically relevant in vitro systems. We sought to develop a 3D cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db0e4daf6069a5854fd0018ec56ce51
http://www.escholarship.org/uc/item/9p95k6vz
http://www.escholarship.org/uc/item/9p95k6vz
Publikováno v:
Cellular Signalling; 25(9), pp 1852-1860 (2013)
Type III receptor tyrosine kinases (RTKs), FLT3 and c-Kit play important roles in a variety of cellular processes. A number of SH2-domain containing proteins interact with FLT3 and c-Kit and regulate downstream signaling. The SH2-domain containing no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3de2cf535eba8dab37e989802ab76
https://doi.org/10.1016/j.cellsig.2013.05.016
https://doi.org/10.1016/j.cellsig.2013.05.016
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells
Autor:
Matilda Munksgaard Thorén, Maria Planck, Sofie Mohlin, Johan Staaf, Martin Johansson, Marica Vaapil, Sven Påhlman
Publikováno v:
Oncotarget
// Matilda Munksgaard Thoren 1 , Marica Vaapil 1, 5 , Johan Staaf 2 , Maria Planck 2, 3 , Martin E. Johansson 4 , Sofie Mohlin 1 and Sven Pahlman 1 1 Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8e5660ea7816c9ff6464fe68bcf026
https://pubmed.ncbi.nlm.nih.gov/28430666
https://pubmed.ncbi.nlm.nih.gov/28430666
Publikováno v:
Upsala Journal of Medical Sciences
The differentiation stage of tumors is a central aspect in the histopathological classification of solid malignancies. The differentiation stage is strongly associated with tumor behavior, and generally an immature tumor is more aggressive than the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68a6aec8869a839b43bd82e4f617a89
http://europepmc.org/articles/PMC3339553
http://europepmc.org/articles/PMC3339553
Publikováno v:
Cancer Research. 71:P5-07
Due to inadequate vascularization and tumor cell proliferation solid tumors are hypoxic compared to corresponding normal tissues. Tumor hypoxia has been associated with increased metastatic potential and worse patient outcome. The hypoxic response is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c13a85d28f55a99ad36810ec03e9c7
https://doi.org/10.1158/0008-5472.sabcs11-p5-07-05
https://doi.org/10.1158/0008-5472.sabcs11-p5-07-05
Autor:
Marianne Sandin, Marie Ovenberger, Marica Vaapil, Sven Påhlman, Kristofer Wårell, Paolo Cifani, Maria Bendz, Peter James, Erik Fredlund, Alexander Pietras, Karin M Hansson, Morten Krogh, Fredrik Levander
Publikováno v:
Journal of proteome research. 10(4)
Nontransient hypoxia is strongly associated with malignant lesions, resulting in aggressive behavior and resistance to treatment. We present an analysis of mRNA and protein expression changes in neuroblastoma cell lines occurring upon the transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec1b6e1bf0fed59f75fbb4e031ae5d0
https://pubmed.ncbi.nlm.nih.gov/21235201
https://pubmed.ncbi.nlm.nih.gov/21235201
Autor:
Drorit Neumann, Anna-Maria Larsson, Sven Påhlman, Lars Rönnstrand, Susann Reinbothe, Jianmin Sun, Marica Vaapil, Caroline Wigerup, Annika Jögi
Publikováno v:
Cancer Research. 74:3464-3464
The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Recombinant human EPO (rhEPO) is therefore used to treat anemia in cancer patients. However, recent clinical trials have indicated that rhEPO trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbd063a0c985c50fa684c286ea41cbc
https://doi.org/10.1158/1538-7445.am2014-3464
https://doi.org/10.1158/1538-7445.am2014-3464
Autor:
Lars Rönnstrand, S. Schiebel, Marica Vaapil, Jianmin Sun, Annika Jögi, S. Påman, Anna-Maria Larsson
Publikováno v:
Annals of Oncology. 23:ii39
The main function of erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis, and recombinant human EPO (rhEPO) is therefore used to treat anemia in cancer patients. Recent clinical trials have indicated that rhEPO treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d46164e3b0501c161d221aa2abd2ef
https://doi.org/10.1016/s0923-7534(19)65732-7
https://doi.org/10.1016/s0923-7534(19)65732-7