Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maribelis Ruiz"'
Autor:
Amy B. Heimberger, Eric C. McGary, Dima Suki, Maribelis Ruiz, Huamin Wang, Gregory N. Fuller, Menashe Bar-Eli
Publikováno v:
Clinical Cancer Research. 11:267-272
Purpose: The activator protein (AP)-2α transcription factor plays a crucial role in the progression of several human tumors, including malignant melanoma, prostate, and breast cancer. Loss of AP-2α results in deregulation of several genes with AP-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2a2b1e742abf9c1a78e3412b67c546
https://doi.org/10.1158/1078-0432.267.11.1
https://doi.org/10.1158/1078-0432.267.11.1
Autor:
Dina Lev, Honnavara N. Ananthaswamy, Maribelis Ruiz, Vladislava O. Melnikova, L. S. Kim, Janet E. Price
Publikováno v:
British Journal of Cancer
One of the major targets for breast cancer therapy is the epidermal growth factor receptor (EGFR) and related receptors, which signal via different signal transduction pathways including the mitogen-activated protein kinase (MAPK) pathway. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc36cf28ef8e21d4113c6926305e5df
http://europepmc.org/articles/PMC2364773
http://europepmc.org/articles/PMC2364773
Autor:
Maribelis Ruiz, Lee M. Ellis, Renduo Song, Menashe Bar-Eli, Curtis A. Pettaway, Oliver Stoeltzing
Publikováno v:
Cancer Research. 64:631-638
Activator protein-2α (AP-2) is a transcription factor that regulates proliferation and differentiation in mammalian cells. We have shown previously that although AP-2 is expressed highly in normal prostatic epithelium, its expression is lost in high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51235e4c4f85f06c7097f29ce508535
https://doi.org/10.1158/0008-5472.can-03-2751
https://doi.org/10.1158/0008-5472.can-03-2751
Autor:
Amy B, Heimberger, Eric C, McGary, Dima, Suki, Maribelis, Ruiz, Huamin, Wang, Gregory N, Fuller, Menashe, Bar-Eli
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(1)
The activator protein (AP)-2alpha transcription factor plays a crucial role in the progression of several human tumors, including malignant melanoma, prostate, and breast cancer. Loss of AP-2alpha results in deregulation of several genes with AP-2alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e6bc123af309f3023df0471223b902c
https://pubmed.ncbi.nlm.nih.gov/15671555
https://pubmed.ncbi.nlm.nih.gov/15671555
Autor:
Claudia P. Miller, Dina Chelouche-Lev, Carmen Tellez, Menashe Bar-Eli, Janet E. Price, Maribelis Ruiz
Publikováno v:
European journal of cancer (Oxford, England : 1990). 40(16)
Elevated expression of pro-angiogenic cytokines is associated with aggressive tumour growth and decreased survival of patients with breast cancer. In general, the breast cancer cell lines with high vascular endothelial growth factor (VEGF) expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de96259d1e6afd0e086b5e3f2efaec8e
https://pubmed.ncbi.nlm.nih.gov/15519527
https://pubmed.ncbi.nlm.nih.gov/15519527
Autor:
Maribelis Ruiz, Vladislava O. Melinkova, Honnavara N. Ananthaswamy, Eric C. McGary, Amir Onn, Dina Lev, Menashe Bar-Eli, Valerie Stone, Claudia P. Miller, Janet E. Price
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 22(11)
Purpose In recent years, the incidence of cutaneous melanoma has increased more than that of any other cancer. Dacarbazine is considered the gold standard for treatment, having a response rate of 15% to 20%, but most responses are not sustained. Prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa42761a468f1ddad2ad106cdf5d70d
https://pubmed.ncbi.nlm.nih.gov/31167092
https://pubmed.ncbi.nlm.nih.gov/31167092
Publikováno v:
The Journal of biological chemistry. 278(47)
Increasing evidence implicates the protease-activated receptor-1 (PAR-1) as a contributor to tumor invasion and metastasis of human melanoma. Here we demonstrate that the metastatic potential of human melanoma cells correlates with overexpression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b10c9aafe82e15dfa20ada9910f5e82
https://pubmed.ncbi.nlm.nih.gov/12975361
https://pubmed.ncbi.nlm.nih.gov/12975361
Autor:
Dina Chelouche, Lev, Maribelis, Ruiz, Lisa, Mills, Eric C, McGary, Janet E, Price, Menashe, Bar-Eli
Publikováno v:
Molecular cancer therapeutics. 2(8)
The incidence of cutaneous malignant melanoma in the United States has increased more than any other cancer in recent years. Chemotherapy for metastatic melanoma is disappointing, there being anecdotal cases of complete remission. Dacarbazine (DTIC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07b2e49d7ae1667e673acbedce2e50c4
https://pubmed.ncbi.nlm.nih.gov/15026559
https://pubmed.ncbi.nlm.nih.gov/15026559
Publikováno v:
Molecular and Cellular Biology
Several reports have linked activating protein 2alpha (AP-2alpha) to apoptosis, leading us to hypothesize that AP-2alpha is a substrate for caspases. We tested this hypothesis by examining the effects of tumor necrosis factor alpha (TNF-alpha) on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db32dc99fbbdb895509c22f5225b7780
https://europepmc.org/articles/PMC87191/
https://europepmc.org/articles/PMC87191/
Autor:
James R. Jabbur, Chang Hun Rhee, Maribelis Ruiz, Kenneth R. Hess, Stephen Chen, Alex Chenchik, Yu Yang, Wei Zhang, Gregory N. Fuller
Publikováno v:
Oncogene. 18(17)
Tumor cell lines are an indispensable tool for cancer research. However, among cell lines of the same pathological group, heterogeneity has been detected in gene expression, gene mutation, and cellular response to various treatments. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd403d9e517a2f114329b4a831f402b
https://pubmed.ncbi.nlm.nih.gov/10348345
https://pubmed.ncbi.nlm.nih.gov/10348345